Relationship between duration of heart failure, patient characteristics, outcomes, and effect of therapy in PARADIGM‐HF

Autor: Su E. Yeoh, Pooja Dewan, Akshay S. Desai, Scott D. Solomon, Jean L. Rouleau, Marty Lefkowitz, Adel Rizkala, Karl Swedberg, Michael R. Zile, Pardeep S. Jhund, Milton Packer, John J.V. McMurray

Publikováno v: ESC Heart Failure, Vol 7, Iss 6, Pp 3355-3364 (2020)

Abstract Aims Little is known about patient characteristics, outcomes, and the effect of treatment in relation to duration of heart failure (HF). We have investigated these questions in PARADIGM‐HF. The aim of the study was to compare patient chara

Externí odkaz: https://doaj.org/article/6b9cd33b5f4844ebbfd23120209dea3b

Relationship between endothelin-1, heart failure with reduced ejection fraction and dapagliflozin: findings from DAPA-HF

Autor: S E Yeoh, K F Docherty, P S Jhund, A Hammarstedt, S E Inzucchi, L Kober, M N Kosiborod, F A Martinez, P Ponikowski, S D Solomon, N Sattar, P Welsh, M S Sabatine, D A Morrow, J J V McMurray

Publikováno v: European Heart Journal. 43

Background Circulating Endothelin-1 (ET-1) is associated with heart failure (HF) severity and has also been widely implicated in the pathophysiology of renal disease. However, its prognostic importance and relationship with kidney function in patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b77df0405a7d9278ae950476346dddfd
https://doi.org/10.1093/eurheartj/ehac544.833

Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways

Autor: A. Cousins, O. Olivares, E. Markert, A. Manoharan, X. Bubnova, S. Bresolin, M. Degn, Z. Li, D. Silvestri, G. McGregor, S. Tumanov, D. Sumpton, J. J. Kamphorst, A. M. Michie, P. Herzyk, M. G. Valsecchi, A. E. Yeoh, K. Schmiegelow, G. te Kronnie, E. Gottlieb, C. Halsey

Publikováno v: Cousins, A, Olivares, O, Markert, E, Manoharan, A, Bubnova, X, Bresolin, S, Degn, M, Li, Z, Silvestri, D, McGregor, G, Tumanov, S, Sumpton, D, Kamphorst, J J, Michie, A M, Herzyk, P, Valsecchi, M G, Yeoh, A E, Schmiegelow, K, te Kronnie, G, Gottlieb, E & Halsey, C 2022, ' Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways ', Leukemia, vol. 36, no. 12, pp. 2903-2907 . https://doi.org/10.1038/s41375-022-01722-x

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66908e5220f89b723d10588796e1cfe2
https://hdl.handle.net/11577/3483125

Temperature drives spatial and temporal variation in the reproductive biology of the blue swimmer crab Portunus armatus A. Milne-Edwards, 1861 (Decapoda: Brachyura: Portunidae)

Autor: Daniel E Yeoh, Danielle Johnston

Publikováno v: Journal of Crustacean Biology. 41

Sound fisheries management requires knowledge of how the reproductive biology of targeted species varies over space and time and responds to external drivers. We determined the size at maturity and fecundity of the blue swimmer crab Portunus armatus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fe189673a49f66b95174382a2eb48d9
https://doi.org/10.1093/jcbiol/ruab032

Abstract 16374: Effect of Dapagliflozin According to Duration of Heart Failure: An Analysis of the DAPA-HF Trial

Autor: F.A Martinez, Mikhail Kosiborod, Olof Bengtsson, John J.V. McMurray, Scott D. Solomon, Lars Køber, Mikaela Sjöstrand, Silvio E. Inzucchi, Piotr Ponikowski, Su E. Yeoh, Anna Maria Langkilde, Pardeep S. Jhund, Marc S. Sabatine, Kieran F. Docherty

Publikováno v: Circulation. 142

Introduction: The relationship between duration of heart failure (HF), patient characteristics, outcomes, and the effect of treatment is largely unknown. We investigated these questions in DAPA-HF. Hypothesis: We hypothesized that longer HF duration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6b336e42e66d1fea06ef3357b01aa7e
https://doi.org/10.1161/circ.142.suppl_3.16374