Zobrazeno 1 - 10
of 366
pro vyhledávání: '"E, Walczak"'
Autor:
Emily E. Binversie, Brian E. Walczak, Stephanie G. Cone, Lauren A. Baker, Tamara A. Scerpella, Peter Muir
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Anterior cruciate ligament (ACL) rupture in humans is a common condition associated with knee pain, joint instability, and secondary osteoarthritis (OA). Surgical treatment with an intraarticular graft provides reasonable outcomes
Externí odkaz:
https://doaj.org/article/9a6d9dac7d574d7dbfdda5475de727c9
Autor:
Brian E. Walczak, DO, PhD, Eamon D. Bernardoni, MD, Quinn Steiner, BS, Geoffrey S. Baer, MD, PhD, Melanie J. Donnelly, MD, John A. Shepler, MD
Publikováno v:
JBJS Open Access, Vol 8, Iss 1 (2023)
Background:. Anterior cruciate ligament reconstruction with hamstring tendon autograft (H-ACLR) is a standard ambulatory procedure with the potential for considerable postoperative pain. We hypothesized that general anesthesia combined with a multimo
Externí odkaz:
https://doaj.org/article/bbc94e153ec54d72a6052d009f3b2c57
294 Identification of MCAK Inhibitors that Induce Aneuploidy in Triple Negative Breast Cancer Models
Autor:
John Smith, Stefan Husted, Jay Pilrose, Disha Kuchangi, Stephanie C. Ems-McClung, Richard L. Carpenter, Claire E. Walczak
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 88-88 (2023)
OBJECTIVES/GOALS: Microtubule poisons, like Taxol, are used to treat triple negative breast cancer (TNBC) and may induce lethal aneuploidy in cancer cells. Patients initially respond, but often develop drug resistance. New targeted drugs that cause a
Externí odkaz:
https://doaj.org/article/f7ae9f0c09394593a916ba7b9b8be76b
Autor:
M. Czubaj-Kowal, T. Friediger, Z. Hudáková, M. Sokołowski, E. Walczak-Kapołka, I. Aštaryová, A. Lesňáková
Publikováno v:
Medičnì Perspektivi, Vol 25, Iss 2, Pp 55-59 (2020)
Nowadays, there are a number of respiratory illnesses that directly affect children. Exhaled nitric oxide measurement (FeNO) is one of the modern methods of investigation used for diagnosing and controlling allergic eosinophilic airway inflammation.
Externí odkaz:
https://doaj.org/article/475d48d5096348aa98a42b861073c0f8
Publikováno v:
Journal of Orthopaedic Translation, Vol 17, Iss , Pp 73-81 (2019)
The discovery of induced pluripotent stem cells (iPSCs) has revolutionized biomedicine. Although the potential of iPSCs for tissue regeneration, disease modeling and drug screening has been largely recognized, findings of iPSC research to date are mo
Externí odkaz:
https://doaj.org/article/78d354069d374be49da1779056d10e99
Autor:
Brian E. Walczak, Kyle Miller, Michael A. Behun, Lisa Sienkiewicz, Heather Hartwig Stokes, Ron McCabe, Geoffrey S. Baer
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Meniscus tears of the knee are among the most common orthopedic knee injury. Specifically, tears of the posterior root can result in abnormal meniscal extrusion leading to decreased function and progressive osteoarthritis. Despite contemporary surgic
Externí odkaz:
https://doaj.org/article/b5536bb62a0a47f3b9b65962ccc786ed
Autor:
Michael D Rotelli, Robert A Policastro, Anna M Bolling, Andrew W Killion, Abraham J Weinberg, Michael J Dixon, Gabriel E Zentner, Claire E Walczak, Mary A Lilly, Brian R Calvi
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008253 (2019)
Endoreplication is a cell cycle variant that entails cell growth and periodic genome duplication without cell division, and results in large, polyploid cells. Cells switch from mitotic cycles to endoreplication cycles during development, and also in
Externí odkaz:
https://doaj.org/article/9b03fb4650ca4d9a83cd8d323520dde5
Importin α/β promote Kif18B microtubule association and enhance microtubule destabilization activity
Autor:
Sanjay Shrestha, Stephanie C. Ems-McClung, Mark A. Hazelbaker, Amber L. Yount, Sidney L. Shaw, Claire E. Walczak
Publikováno v:
Molecular Biology of the Cell. 34
The critical regions of interaction between the Kif18B tail and its binding partners, importin α/β and EB1, are defined, and it is shown how these interactions control Kif18B function in cells and activity in vitro. A new mechanism is uncovered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::374b394f8812d20720ca8592f644e1bf
https://doi.org/10.1091/mbc.e22-03-0113
https://doi.org/10.1091/mbc.e22-03-0113
Publikováno v:
Journal of Pediatric Orthopaedics. 42:e747-e752
Softball is a popular sport among youth female athletes. While youth baseball has well-established, evidence-based pitching guidelines, youth softball pitching guidelines lack both evidence and enforcement. Adherence to pitch count limits in youth so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8f9a4af832a571a67e21162c9ec39c
https://doi.org/10.1097/bpo.0000000000002182
https://doi.org/10.1097/bpo.0000000000002182
Publikováno v:
Cartilage
Objectives Functions of mesenchymal stem/stromal cells (MSCs) are affected by patient-dependent factors such as age and health condition. To tackle this problem, we used the cellular reprogramming technique to epigenetically alter human MSCs derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680ba68e26d5907b9b5b860333d832c3
https://doi.org/10.1177/19476035211040858
https://doi.org/10.1177/19476035211040858