Zobrazeno 1 - 10
of 1 268
pro vyhledávání: '"E, Vokes"'
Autor:
James M. Dolezal, Andrew Srisuwananukorn, Dmitry Karpeyev, Siddhi Ramesh, Sara Kochanny, Brittany Cody, Aaron S. Mansfield, Sagar Rakshit, Radhika Bansal, Melanie C. Bois, Aaron O. Bungum, Jefree J. Schulte, Everett E. Vokes, Marina Chiara Garassino, Aliya N. Husain, Alexander T. Pearson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Safe clinical deployment of deep learning models for digital pathology requires reliable estimates of predictive uncertainty. Here the authors describe an algorithm for quantifying whole-slide image uncertainty, demonstrating their approach with mode
Externí odkaz:
https://doaj.org/article/3782f0100a0e42dd916744ca0dcd64bc
Autor:
Ari J. Rosenberg, Evgeny Izumchenko, Alexander Pearson, Zhen Gooi, Elizabeth Blair, Theodore Karrison, Aditya Juloori, Daniel Ginat, Nicole Cipriani, Mark Lingen, Hillary Sloane, Daniel L. Edelstein, Kirsten Keyser, Johannes Fredebohm, Frank Holtrup, Frederick S. Jones, Daniel Haraf, Nishant Agrawal, Everett E. Vokes
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) has a favorable prognosis which has led to efforts to de-intensify treatment. Response-adaptive de-escalated treatment is promising, however improved biomarkers are
Externí odkaz:
https://doaj.org/article/9a900a0e9acd46aa9f1e55c493688248
Autor:
Stanley I. Gutiontov, William Tyler Turchan, Liam F. Spurr, Sherin J. Rouhani, Carolina Soto Chervin, George Steinhardt, Angela M. Lager, Pankhuri Wanjari, Renuka Malik, Philip P. Connell, Steven J. Chmura, Aditya Juloori, Philip C. Hoffman, Mark K. Ferguson, Jessica S. Donington, Jyoti D. Patel, Everett E. Vokes, Ralph R. Weichselbaum, Christine M. Bestvina, Jeremy P. Segal, Sean P. Pitroda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Immune checkpoint blockade (ICB) improves outcomes in non-small cell lung cancer (NSCLC) though most patients progress. There are limited data regarding molecular predictors of progression. In particular, there is controversy regarding the r
Externí odkaz:
https://doaj.org/article/82195ffa5c7b45b097938796d4698839
Autor:
Thomas A. Hensing, MD, MS, Xiaofei Wang, PhD, Thomas E. Stinchcombe, MD, Junheng Gao, MS, Michael V. Knopp, MD, PhD, Mark Watson, MD, PhD, Arkadiusz Z. Dudek, MD, PhD, Stephen L. Graziano, MD, Jyoti D. Patel, MD, Bryan A. Faller, MD, Konstantin H. Dragnev, MD, David Kozono, MD, PhD, Everett E. Vokes, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 8, Pp 100208- (2021)
Introduction: The sequence of chemotherapy and pembrolizumab may affect antitumor immune response and efficacy of immunotherapy. Methods: This multicenter, randomized, phase 2 trial was designed to evaluate the efficacy of two sequences of chemothera
Externí odkaz:
https://doaj.org/article/df3a2223967b484e8c1430c2888b54cb
Autor:
Misha C. Tran, Garth W. Strohbehn, Theodore G. Karrison, Sherin J. Rouhani, Jeremy P. Segal, Ardaman Shergill, Philip C. Hoffman, Jyoti D. Patel, Marina C. Garassino, Everett E. Vokes, Christine M. Bestvina
Publikováno v:
Clinical Lung Cancer. 24:e117-e121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16641b0206eeb48ca714ee08220bc5fe
https://doi.org/10.1016/j.cllc.2023.01.003
https://doi.org/10.1016/j.cllc.2023.01.003
Autor:
Patrick M Forde, Jonathan Spicer, Shun Lu, Mariano Provencio, Tetsuya Mitsudomi, Mark M Awad, Enriqueta Felip, Stephen R Broderick, Julie R Brahmer, Scott J Swanson, Keith Kerr, Changli Wang, Tudor–Eliade Ciuleanu, Gene B Saylors, Fumihiro Tanaka, Hiroyuki Ito, Ke Neng Chen, Moishe Liberman, Everett E Vokes, Janis M Taube, Cecile Dorange, Junliang Cai, Joseph Fiore, Anthony Jarkowski, David Balli, Mark Sausen, Dimple Pandya, Christophe Y Calvet, Nicolas Girard
Publikováno v:
Future Oncology. 19:549-557
What is this summary about? In this article, we summarize results from the ongoing phase 3 CheckMate 816 clinical study that were published in The New England Journal of Medicine in 2022. The goal of CheckMate 816 was to find out if nivolumab, an imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dae900a445d2aaedbeebb7457a197cef
https://doi.org/10.2217/fon-2023-0007
https://doi.org/10.2217/fon-2023-0007
Autor:
Alexander Huelsen, Andrew T. St John, Ratna Pandey, David E. Vokes, Jessica J. McMaster, Russell S. Walmsley, Gerald J. Holtmann
Publikováno v:
Endoscopy International Open, Vol 09, Iss 02, Pp E154-E162 (2021)
Background and study aims A structured assessment of the oropharynx, hypopharynx and larynx (OHL) may improve the diagnostic yield for the detection of precancerous and early cancerous lesions (PECLs) during routine esophagogastroduodenoscopy (EGD).
Externí odkaz:
https://doaj.org/article/fac6a6ab89004e4891d838d4393da993
Autor:
Natalie Reizine, Everett E. Vokes, Ping Liu, Tien M. Truong, Rita Nanda, Gini F. Fleming, Daniel V.T. Catenacci, Alexander T. Pearson, Sandeep Parsad, Keith Danahey, Xander M. R. van Wijk, Kiang-Teck J. Yeo, Mark J. Ratain, Peter H. O’Donnell
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Many cancer patients who receive chemotherapy experience adverse drug effects. Pharmacogenomics (PGx) has promise to personalize chemotherapy drug dosing to maximize efficacy and safety. Fluoropyrimidines and irinotecan have well-known ge
Externí odkaz:
https://doaj.org/article/a4fbb785a980432cbc1cd3da35a7b36b
Autor:
Liam F. Spurr, Carlos A. Martinez, Wenjun Kang, Mengjie Chen, Yuanyuan Zha, Robyn Hseu, Stanley I. Gutiontov, William T. Turchan, Connor M. Lynch, Kelli B. Pointer, Paul Chang, Septimiu Murgu, Aliya N. Husain, Brittany Cody, Everett E. Vokes, Christine M. Bestvina, Jyoti D. Patel, Maximilian Diehn, Thomas F. Gajewski, Ralph R. Weichselbaum, Steven J. Chmura, Sean P. Pitroda
Publikováno v:
Nature Cancer. 3:1498-1512
Over 500 clinical trials are investigating combination radiotherapy and immune checkpoint blockade (ICB) as cancer treatments; however, the majority of trials have found no positive interaction. Here we perform a comprehensive molecular analysis of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea81f62ca731e975d213be7de47fdaa
https://doi.org/10.1038/s43018-022-00467-x
https://doi.org/10.1038/s43018-022-00467-x
Autor:
Cherie-Ann O. Nathan, D. Neil Hayes, Theodore Karrison, Olivier Harismendy, José M. Flores, Tara Moore-Medlin, Everett E. Vokes, J. Silvio Gutkind, Prakash Neupane, Glenn Mills, Zoukaa Sargi, Tanguy Seiwert, Juneko Grilley-Olson, Terry Day, Maura Gillison, James L. Wade, Lawrence Feldman, Gautam Jha, Mark Kozloff, Miriam O'Leary, Francis P. Worden, Ezra E.W. Cohen
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 23
Clin Cancer Res
Clin Cancer Res
Purpose: Investigate whether adjuvant everolimus, an mTOR inhibitor, improves progression-free survival (PFS) in advanced-stage head and neck squamous cell carcinoma (HNSCC) and provide outcomes related to correlative biological factors associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0370f301ad46efff6a4eb5a25479bea5
https://doi.org/10.1158/1078-0432.ccr-21-4290
https://doi.org/10.1158/1078-0432.ccr-21-4290