Zobrazeno 1 - 10 of 432 pro vyhledávání: '"E, Van Herck"'
1
Enhanced Immunoreceptor Tyrosine-based Activation Motif Signaling is Related to Pathological Bone Resorption During Critical Illness
Autor: A. Wauters, Jan Gunst, E Van Herck, Helen C. Owen, S. Van Cromphaut, G Van den Berghe, I. Vanhees, Thomas Janssens
Publikováno v: Hormone and Metabolic Research
Prolonged critically ill patients present with distinct alterations in calcium and bone metabolism. Circulating bone formation markers are reduced and bone resorption markers are substantially elevated, indicating an uncoupling between osteoclast and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74117b0e1959cd27635ae04d99c2e4d
https://doi.org/10.1055/s-0033-1351290
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2
Akademický článek
Immune dynamics shaping pre-metastatic and metastatic niches in liver metastases: from molecular mechanisms to therapeutic strategies.
Autor: Zhu, Chang1,2 (AUTHOR), Liao, Jing-Yu1,2 (AUTHOR), Liu, Yi-Yang1,2 (AUTHOR), Chen, Ze-Yu1,2 (AUTHOR), Chang, Rui-Zhi1,2 (AUTHOR), Chen, Xiao-Ping1,2 (AUTHOR), Zhang, Bi-Xiang1,2 (AUTHOR) bixiangzhang@hust.edu.cn, Liang, Jun-Nan1,2 (AUTHOR) liangjunnan@tjh.tjmu.edu.cn
Publikováno v: Molecular Cancer. 11/14/2024, Vol. 23 Issue 1, p1-25. 25p.
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3
Akademický článek
Single-cell and bulk transcriptome analysis reveals tumor cell heterogeneity and underlying molecular program in uveal melanoma.
Autor: Li, Ke1,2 (AUTHOR), Huang, Jingzhe1,2 (AUTHOR), Tan, Ying1,2 (AUTHOR), Sun, Jie1,2 (AUTHOR) suncarajie@wmu.edu.cn, Zhou, Meng1,2 (AUTHOR) zhoumeng@wmu.edu.cn
Publikováno v: Journal of Translational Medicine. 11/12/2024, Vol. 22 Issue 1, p1-15. 15p.
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4
Increased bone formation in mice lacking plasminogen activators
Autor: Roger Bouillon, G Carmeliet, Sophie Torrekens, E Van Herck, Vincent Everts, W Tigchelaar-Gutterr, E Daci
Publikováno v: Journal of Bone and Mineral Research, 18, 1167-1176. Wiley-Blackwell
Journal of Bone and Mineral Research, 18, 1167-1176. American Society for Bone and Mineral Research
Daci, E, Everts, V, Torrekens, S, van Herck, E, Tigchelaar-Gutter, W, Bouillon, R & Carmeliet, P 2003, ' Increased bone formation in mice lacking plasminogen activators ', Journal of Bone and Mineral Research, vol. 18, pp. 1167-1176 . https://doi.org/10.1359/jbmr.2003.18.7.1167
Journal of bone and mineral research, 18(7), 1167-1176. Wiley-Blackwell
Plasminogen activators tPA and uPA are involved in tissue remodeling, but their role in bone growth is undefined. Mice lacking tPA and uPA show increased bone formation and bone mass. The noncollagenous components of bone matrix are also increased, p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3ffd8a7aa3f9168ab336b68c81bf10
https://hdl.handle.net/11245/1.218757
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5
The Estrogen Receptor Ligand ICI 182,780 Does Not Impair the Bone-Sparing Effects of Testosterone in the Young Orchidectomized Rat Model
Autor: Dirk Vanderschueren, Johannes V. Swinnen, Roger Bouillon, E Van Herck, Liesbeth Vandenput, Annemieke Verstuyf, Steven Boonen
Publikováno v: Calcified Tissue International. 70:170-175
Testosterone (T) can affect bone metabolism not only directly, but also via its metabolites, estrogen or dihydrotestosterone, produced by enzymes present in bone. Therefore, the aim of this study was to investigate whether the high-affinity estrogen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b720418e88004c547322082298a032
https://doi.org/10.1007/s00223-001-2065-z
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6
Testosterone Prevents Orchidectomy-Induced Bone Loss in Estrogen Receptor-α Knockout Mice
Autor: E Van Herck, Johan F.M. Swinnen, K Stahr, Liesbeth Vandenput, Annemieke Verstuyf, Dirk Vanderschueren, Roger Bouillon, Reinhold G. Erben, Steven Boonen, A. G. H. Ederveen
Publikováno v: Biochemical and Biophysical Research Communications. 285:70-76
To examine the role of the estrogen receptor-alpha (ERalpha) during male skeletal development, bone density and structure of aged ERalphaKO mice and wild-type (WT) littermates were analyzed and skeletal changes in response to sex steroid deficiency a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c6591521cff4f26435e1a4ed8c621e
https://doi.org/10.1006/bbrc.2001.5101
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7
Skeletal effects of estrogen deficiency as induced by an aromatase inhibitor in an aged male rat model
Autor: E Van Herck, Liesbeth Vandenput, Annemieke Verstuyf, A. G. H. Ederveen, R. De Coster, Roger Bouillon, Steven Boonen, Karen Moermans, Dirk Vanderschueren
Publikováno v: Bone. 27:611-617
Aromatization of androgens into estrogens may be important for maintenance of the male skeleton. To address this hypothesis, we evaluated the skeletal effects of selective estrogen deficiency as induced by the aromatase inhibitor vorozole (Vor), with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501c9584ebc47d23af182feed8212b81
https://doi.org/10.1016/s8756-3282(00)00363-x
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8
Calciotrophic hormones during experimental hypocalcaemia and hypercalcaemia in spontaneously diabetic rats
Autor: Johan Verhaeghe, Roger Bouillon, Z Zaman, R. Van Bree, Ivo Jans, E Van Herck
Publikováno v: Journal of Endocrinology. 162:251-258
1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) concentrations have been found to be decreased in diabetic humans and rats. To investigate further the regulation of plasma Ca in diabetes, first we measured Ca(2+), P, Mg, parathyroid hormone(1-34) (PTH),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a519bd69b68097783f37c32fdcd87a1
https://doi.org/10.1677/joe.0.1620251
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9
IGF-I, IGF-II, IGF Binding Protein 1, and C-Peptide in Second Trimester Amniotic Fluid Are Dependent on Gestational Age but Do Not Predict Weight at Birth
Autor: Ingrid Witters, D. Van Schoubroeck, Jan Deprest, E Van Herck, Willy Coopmans, Johan Verhaeghe
Publikováno v: Pediatric Research. 46:101-108
Previous data suggested that small for gestational age newborns have increased levels of IGF binding protein 1 (IGFBPI) in amniotic fluid (AF) at 15-16 wk of pregnancy. In this study, we developed an RIA for IGFBP1 and measured IGFBP1 concentrations
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04939232d646316752d27a2a7f8ff591
https://doi.org/10.1203/00006450-199907000-00017
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10
Pathogenesis of Fetal Hypomineralization in Diabetic Rats: Evidence for Delayed Bone Maturation
Autor: Johan Verhaeghe, R. Van Bree, E Van Herck, Katrien Rummens, Robert Pijnenborg, Lisbeth Vercruysse, Roger Bouillon
Publikováno v: Pediatric Research. 45:209-217
There is some evidence that fetuses of diabetic rats (FDR) are hypomineralized. To explore the pathogenic role of decreased maternal duodenal Ca absorption, fetal hypotrophy, and decreased placental calbindin-D9K, respectively, spontaneously diabetic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52ea5888b679040cfb0c6de6362b8e8
https://doi.org/10.1203/00006450-199902000-00009
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