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Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells

Autor: W R, Wan Makhtar, G, Browne, A, Karountzos, C, Stevens, Y, Alghamdi, A R, Bottrill, S, Mistry, E, Smith, M, Bushel, J H, Pringle, A E, Sayan, E, Tulchinsky

Publikováno v: Oncogene

Two proteins comprising the ZEB family of zinc finger transcription factors, ZEB1 and ZEB2, execute EMT programs in embryonic development and cancer. By studying regulation of their expression, we describe a novel mechanism that limits ZEB2 protein s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0f38474089e9f4c1ec74f9a25fcfae55
https://pubmed.ncbi.nlm.nih.gov/28783176

Abstracts from the 2011 BNOS Conference, June 29 - July 1, 2011, Homerton College, Cambridge

Autor: S. Ammoun, L. Zhou, M. Barczyk, D. Hilton, S. Hafizi, C. Hanemann, K. S. Lehnus, L. K. Donovan, G. J. Pilkington, Q. An, I. A. Anderson, S. Thomson, M. Bailey, E. Lekka, J. Law, C. Davis, K. Banfill, C. Loughrey, P. Hatfield, D. Bax, R. Elliott, R. Bishop, K. Taylor, L. Marshall, N. Gaspar, M. Viana-Pereira, R. Reis, J. Renshaw, A. Ashworth, C. Lord, C. Jones, C. Bellamy, L. Shaw, J. Alder, A. Shorrocks, R. Lea, S. Birks, M. Burnet, G. Pilkington, J. D. Bruch, J. Ho, C. Watts, S. J. Price, S. Camp, V. Apostolopoulos, A. Mehta, F. Roncaroli, D. Nandi, B. Clark, M. Mackinnon, N. MacLeod, W. Stewart, A. Chalmers, A. Cole, G. Hanna, K. Bailie, D. Conkey, J. Harney, C. Darlow, S. Chapman, L. Mohsen, S. Price, L. Donovan, H. Dyer, H. Lord, K. Fletcher, R. das Nair, J. MacNiven, S. Basu, P. Byrne, L. Glancz, G. Critchley, M. Grech-Sollars, D. Saunders, K. Phipps, J. Clayden, C. Clark, A. Greco, S. Acquati, S. Marino, S. Hammouche, S. P. Wilkins, T. Smith, A. Brodbelt, S. Clark, A. H. L. Wong, P. Eldridge, J. O. Farah, J. Bruch, G. Lamb, S. Smith, A. James, M. Glegg, T. Jeffcote, S. Boulos, P. Robbins, N. Knuckey, A. Banigo, A. R. Brodbelt, M. D. Jenkinson, J. N. Jeyapalan, M. A. Mumin, T. Forshew, A. R. Lawson, R. G. Tatevossian, T. S. Jacques, D. Sheer, J. Kilday, K. Wright, S. Leavy, J. Lowe, E. Schwalbe, S. Clifford, R. Gilbertson, B. Coyle, R. Grundy, P. Kinsella, M. Clynes, V. Amberger-Murphy, N. Barron, S. R. Lambert, D. Jones, D. Pearson, I. Ichimura, V. Collins, L. Steele, P. Sinha, P. Chumas, J. Tyler, D. Ogawa, E. Chiocca, M. DeLay, A. Bronisz, M. Nowicki, J. Godlewski, S. Lawler, M. K. Lee, M. Javadpour, P. Abel, T. Dawson, B. Lea, C. S.-K. Lim, P. L. Grundy, M. Pendleton, A. Williamson, A. Merve, X. Zhang, S. Miller, H. A. Rogers, P. Lyon, V. Rand, M. Adamowicz-Brice, S. C. Clifford, J. T. Hayden, S. Dyer, S. Pfister, A. Korshunov, M.-A. Brundler, R. G. Grundy, M. Nankivell, P. Mulvenna, R. Barton, P. Wilson, C. Faivre-Finn, C. Pugh, R. Langley, D. Ngoga, D. Tennant, A. Williams, P. Moss, G. Cruickshank, K. Owusu-Agyemang, S. Bell, J. St.George, S. G. Piccirillo, S. Qadri, E. Pirola, M. Jenkinson, R. Rahman, C. Rahman, D. MacArthur, F. Rose, K. Shakesheff, C. Carroll, P. Watson, M. Hawkins, H. Spoudeas, D. Walker, T. Holland, H. Ring, A. Rooney, S. McNamara, M. Fraser, R. Rampling, A. Carson, R. Grant, J. Royds, S. Al Nadaf, A. Ahn, Y.-J. Chen, A. Wiles, D. Jellinek, A. Braithwaite, B. Baguley, M. MacFarlane, N. Hung, T. Slatter, S. Rusbridge, N. Walmsley, S. Griffiths, P. Wilford, J. Rees, D. Ryan, P. Liu, S. Galavotti, M. Shaked-Rabi, E. Tulchinsky, S. Brandner, P. Salomoni, A. Schulte, H. S. Gunther, S. Zapf, S. Riethdorf, M. Westphal, K. Lamszus, S. K. Selvanathan, H. J. Salminen, S. Setua, M. E. Welland, M. Shevtsov, W. Khachatryan, A. Kim, K. Samochernych, A. Pozdnyakov, I. V. Guzhova, I. V. Romanova, B. Margulis, J. Barrow, D. Macarthur, A. Long, Z. Maherally, J. R. Smith, L. Dickson, S. Prabhu, F. Harris, T. J. Snape, M. Sussman, S. Wilne, W. Whitehouse, G. Chow, J.-F. Liu, T. Snape, A. Karakoula, F. Rowther, T. Warr, A. Zisakis, V. Varsos, A. Panteli, O. Karypidou, A. Zampethanis, A. Fotovati, S. Abu-Ali, P.-S. Wang, L. Deleyrolle, C. Lee, J. Triscott, J. Y. Chen, S. Franciosi, Y. Nakamura, Y. Sugita, T. Uchiumi, M. Kuwano, B. R. Leavitt, S. K. Singh, A. Jury, H. Wakimoto, B. A. Reynolds, C. J. Pallen, S. E. Dunn, S. Shepherd, S. Scott, D. Bowyer, L. Wallace, B. Hacking, R. Jena, J. Gillard, M. Verraeult, B. Reynolds, C. Dunham, M. Bally, J. Hukin, S. Singhal, S. Singh, S. Dunn

Publikováno v: Neuro-Oncology. 13:ii1-ii14

INTRODUCTION: Substituted indoles and related structures have been shown to exhibit potent anticancer activity against breast cancer cell lines. Here, the effects of structurally similar substituted indoles against the human glial cancer cell lines,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd03645d5059bcd6cdb359145b1432b
https://doi.org/10.1093/neuonc/nor144

Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction

Autor: M, Grigorian, S, Andresen, E, Tulchinsky, M, Kriajevska, C, Carlberg, C, Kruse, M, Cohn, N, Ambartsumian, A, Christensen, G, Selivanova, E, Lukanidin

Publikováno v: The Journal of biological chemistry. 276(25)

A physical and functional interaction between the Ca(2+)-binding protein Mts1 (S100A4) and the tumor suppressor p53 protein is shown here for the first time. We demonstrate that Mts1 binds to the extreme end of the C-terminal regulatory domain of p53

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::125f42d5def98f0173a8349c123259dd
https://pubmed.ncbi.nlm.nih.gov/11278647

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