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Akademický článek

Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system.

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96092 (2014)

The constitutive active/androstane receptor (CAR) plays an important role as a coordinate transcription factor in the regulation of various hepatic metabolic pathways for chemicals such as drugs, glucose, fatty acids, bilirubin, and bile acids. Curre

Externí odkaz: https://doaj.org/article/96ef23f5d40e41e590629a496556be72

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Outpatient Management of Patients With COVID-19: Multicenter Prospective Validation of the Hospitalization or Outpatient Management of Patients With SARS-CoV-2 Infection Rule to Discharge Patients Safely

Autor: Delphine Douillet, Andrea Penaloza, Rafaël Mahieu, François Morin, Anthony Chauvin, Stéphane Gennai, Thibault Schotte, Emmanuel Montassier, Pierre-Clément Thiebaud, Alexandre Ghuysen François, David Dall’acqua, Kasarra Benhammouda, Pascal Bissokele, Mathieu Violeau, Luc-Marie Joly, Hery Andrianjafy, Caroline Soulie, Dominique Savary, Jérémie Riou, Pierre-Marie Roy, H. Andrianjafy, L. Baudin, K. Benhammouda, P. Bissolokele, C. Brice, C. Cayeux, E. Casalino, C. Casarin, A. Chauvin, C. Choquet, Y.-E. Claessens, Francis Couturaud, D. Dall’acqua, B. Dobanton, D. Douillet, F. Dupriez, X. Eyer, L. Ferrand, S. Gennai, A. Ghuysen, A. Greau-Chauchet, L.-M. Joly, H.-H. Karam, M. Layot, A. Leroy, R. Lopez, R. Mahieu, N. Marchant, N. Marjanovic, E. Montassier, F. Morin, Baeza A. Penaloza, G. Plantefeve, P.-M. Roy, D. Savary, J. Schmidt, T. Schotte, M. Sebbane, C. Soulie, L. Soulat, C. Steiner, P.-C. Thiebaud, E. Timsit, E. Trabattoni, M. Violeau

Publikováno v: Chest, Vol. 160, no. 4, p. 1222-1231 (2021)
Chest
Chest, Vol. 160, no.4, p. 1222-1231 (2021)

BACKGROUND: The Hospitalization or Outpatient Management of Patients With SARS-CoV-2 Infection (HOME-CoV) rule is a checklist of eligibility criteria for home treatment of patients with COVID-19, defined using a Delphi method. RESEARCH QUESTION: Is t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aed5aa97baf8fb2889d1456308808e8
https://hdl.handle.net/2078.1/261338

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Effects of calfhood respiratory disease on health and performance of dairy cattle: A systematic review and meta-analysis

Autor: Sébastien Buczinski, D. Achard, E. Timsit

Publikováno v: Journal of dairy science. 104(7)

Bovine respiratory disease (BRD) is one of the most common calfhood diseases in dairy cattle. Unfortunately, published data on the short- and long-term effects of calfhood BRD on health and performance are scarce and, when available, often conflictin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07a03b24beaae53b051304e10f5462a
https://pubmed.ncbi.nlm.nih.gov/33896639

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Une dermatose au shiitake

Autor: E. Timsit, E. Humblot, P. Ray

Publikováno v: Annales françaises de médecine d’urgence. 11:51-52

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b8938a29c55f60b4919d55277926b4c
https://doi.org/10.3166/afmu-2020-0273

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Essential oils inhibit the bovine respiratory pathogens Mannheimia haemolytica, Pasteurella multocida and Histophilus somni and have limited effects on commensal bacteria and turbinate cells in vitro

Autor: S, Amat, D, Baines, E, Timsit, J, Hallewell, T W, Alexander

Publikováno v: Journal of applied microbiology. 126(6)

The objective of this study was to determine antimicrobial activities of essential oils (EOs) against bovine respiratory disease (BRD) pathogens and nasopharyngeal commensal bacteria, as well as cytotoxicity in bovine turbinate (BT) cells in vitro.Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c5f8dafded5b1c4324895feca96bd03e
https://pubmed.ncbi.nlm.nih.gov/30817050

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Colony-Stimulating Factor-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes

Autor: Yinuo Pang, Gaetane Woerly, Esther Sutter, Francois Pognan, Ursula Schramm, Yoav E Timsit, Marie Anne Valentin, Philippe Couttet, Armin Wolf, Beate Vogel, Ivan Demin, Birgit Jaitner, Ronenn Roubenoff

Publikováno v: The Journal of pharmacology and experimental therapeutics. 369(3)

The colony-stimulating factor-1 (CSF-1) receptor pathway has been implicated in a variety of diseases, and CSF-1-dependent mechanisms are also involved in bloodborne protein clearance. Lacnotuzumab is a novel, high-affinity, humanized, anti-CSF-1 mon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef69e48a10a90d3ac1e1ed0857b5eac9
https://pubmed.ncbi.nlm.nih.gov/30894455

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Akademický článek

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Akademický článek

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CAR and PXR: The xenobiotic-sensing receptors☆

Autor: Yoav E. Timsit, Masahiko Negishi

Publikováno v: Steroids. 72:231-246

The xenobiotic receptors CAR and PXR constitute two important members of the NR1I nuclear receptor family. They function as sensors of toxic byproducts derived from endogenous metabolism and of exogenous chemicals, in order to enhance their eliminati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08b5229b02147ccce5fc39c97fc82a6
https://doi.org/10.1016/j.steroids.2006.12.006

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