Zobrazeno 1 - 10
of 35
pro vyhledávání: '"E, Stefanich"'
Autor:
S. Pippig, G. P. Coffey, S. Palmieri, J. Padilla-Eagar, R. Eckert, E. Stefanich, Paul J. Fielder
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 310(3)
Efalizumab (Raptiva) is a humanized CD11a-specific monoclonal antibody that was recently approved for the treatment of moderate to severe psoriasis. In psoriasis patients, the rate of efalizumab clearance from serum is related to T-cell surface expre
Autor:
P J, Fielder, P, Hass, M, Nagel, E, Stefanich, R, Widmer, G L, Bennett, G A, Keller, F J, de Sauvage, D, Eaton
Publikováno v:
Blood. 89(8)
Recent studies have shown that plasma thrombopoietin (TPO) levels appear to be directly regulated by platelet mass and that removal of plasma TPO by platelets via binding to the c-Mpl receptor is involved in the clearance of TPO in rodents. To help e
Autor:
P J, Fielder, A L, Gurney, E, Stefanich, M, Marian, M W, Moore, K, Carver-Moore, F J, de Sauvage
Publikováno v:
Blood. 87(6)
The involvement of platelets and the c-mpl receptor in the regulation of thrombopoietin (TPO) plasma concentrations and tissue mRNA levels was investigated in both normal mice and mice defective in c-mpl (c-mpl-/-). Although c-mpl-/- mice have fewer
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; September 2004, Vol. 310 Issue: 3 p896-904, 9p
Autor:
Tao X; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Sukumaran S; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA; Now at Janssen: Pharmaceutical Companies of Johnson & Johnson, 1125 Trenton-Harbourton Road, Titusville, NJ 08560, USA., Sperinde G; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Liu C; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Beardsley MI; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Day P; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Kalo M; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Ayewoh E; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Cai H; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Wang Y; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA; Now at Gilead Sciences, Inc, 333 Lakeside Drive. Foster City, CA 94404, USA., Jun I; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA; Now at University of Florida, Gainesville, FL 32611, USA., Hirst K; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Nguyen V; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Chung S; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Lee D; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Lekkerkerker A; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Stefanich E; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: stefanich.eric@gene.com.
Publikováno v:
Journal of pharmaceutical sciences [J Pharm Sci] 2024 Jul; Vol. 113 (7), pp. 1975-1986. Date of Electronic Publication: 2024 Mar 30.
Autor:
Cai H; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Tao X; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Shim J; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Bauer RN; OMNI Biomarker Development, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Bremer M; OMNI Biomarker Development, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Bu W; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., LaMar J; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Basile R; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Dere E; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Nguyen T; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Laing S; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Chan P; Biochemical and Cellular Pharmacology, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Yi T; Discovery Immunology, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Koerber JT; Antibody Engineering, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Sperinde G; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Stefanich E; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA. stefanich.eric@gene.com.
Publikováno v:
The AAPS journal [AAPS J] 2023 Jun 23; Vol. 25 (4), pp. 64. Date of Electronic Publication: 2023 Jun 23.
Autor:
Kim TW; Asan Medical Center, University of Ulsan, Seoul, Korea., Burris HA; Sarah Cannon Research Institute, Nashville, Tennessee., de Miguel Luken MJ; START-CIOCC, Hosp. HM Sanchinarro, Madrid, Spain., Pishvaian MJ; Johns Hopkins University School of Medicine, Washington, DC., Bang YJ; Seoul National University College of Medicine, Seoul, Korea., Gordon M; HonorHealth Research Institute, Scottsdale, Arizona., Awada A; Jules Bordet Institute, Brussels, Belgium., Camidge DR; University of Colorado Anschutz Medical Campus, Aurora, Colorado., Hodi FS; Dana-Farber Cancer Institute, Boston, Massachusetts., McArthur GA; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Miller WH; Jewish General Hospital and Segal Cancer Centre, McGill University, Montréal, Canada., Cervantes A; Biomedical Research Institute INCLIVA, University of Valencia, Valencia Spain., Chow LQ; University of Washington, Seattle, Washington., Lesokhin AM; Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Rutten A; GasthuisZusters Antwerpen Sint-Augustinus, Antwerp, Belgium., Sznol M; Yale School of Medicine, New Haven, Connecticut., Rishipathak D; Genentech, Inc., South San Francisco, California., Chen SC; Genentech, Inc., South San Francisco, California., Stefanich E; Genentech, Inc., South San Francisco, California., Pourmohamad T; Genentech, Inc., South San Francisco, California., Anderson M; Genentech, Inc., South San Francisco, California., Kim J; Genentech, Inc., South San Francisco, California., Huseni M; Genentech, Inc., South San Francisco, California., Rhee I; Genentech, Inc., South San Francisco, California., Siu LL; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Aug 15; Vol. 28 (16), pp. 3452-3463.
Autor:
Cohen S; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Chung S; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Spiess C; Department of Antibody Engineering, Genentech Inc, South San Francisco, CA, USA., Lundin V; Department of Protein Analytical Chemistry, Genentech Inc, South San Francisco, CA, USA., Stefanich E; Genentech Inc, South San Francisco, CA, USA., Laing ST; Department of Safety Assessment, Genentech Inc, South San Francisco, CA, USA., Clark V; Department of Safety Assessment, Genentech Inc, South San Francisco, CA, USA., Brumm J; Department of Biostatistics, Genentech Inc, South San Francisco, CA, USA., Zhou Y; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Huang C; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Guerrero J; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Myneni S; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Yadav R; Genentech Inc, South San Francisco, CA, USA., Siradze K; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Peng K; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA.
Publikováno v:
MAbs [MAbs] 2021 Jan-Dec; Vol. 13 (1), pp. 1944017.
Autor:
Hosseini I; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Gadkar K; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Stefanich E; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Li CC; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Sun LL; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Chu YW; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Ramanujan S; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. ramanujan.saroja@gene.com.
Publikováno v:
NPJ systems biology and applications [NPJ Syst Biol Appl] 2020 Aug 28; Vol. 6 (1), pp. 28. Date of Electronic Publication: 2020 Aug 28.
Autor:
Rothenberg ME; Genentech, Inc., South San Francisco, California,, USA., Wang Y; Genentech, Inc., South San Francisco, California,, USA., Lekkerkerker A; Genentech, Inc., South San Francisco, California,, USA., Danilenko DM; Genentech, Inc., South San Francisco, California,, USA., Maciuca R; Genentech, Inc., South San Francisco, California,, USA., Erickson R; Genentech, Inc., South San Francisco, California,, USA., Herman A; Genentech, Inc., South San Francisco, California,, USA., Stefanich E; Genentech, Inc., South San Francisco, California,, USA., Lu TT; Genentech, Inc., South San Francisco, California,, USA.
Publikováno v:
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2019 Jan; Vol. 105 (1), pp. 177-189. Date of Electronic Publication: 2018 Aug 12.