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Publikováno v:
Journal of Pediatric Urology. 5:308-314
Renal cell carcinoma (RCC) comprises about 5% of pediatric renal neoplasms. It has been recognized as a second malignancy in multiple reports. It is generally symptomatic at diagnosis, and most children with RCC present with more locally advanced dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2546d9cbfbb6ba60f70cd5d39fb9e7e7
https://doi.org/10.1016/j.jpurol.2009.04.007
https://doi.org/10.1016/j.jpurol.2009.04.007
Autor:
Maryalice Stetler-Stevenson, Mark Raffeld, Douglas W. Kingma, Paula D. Imus, Robert J. Kreitman, David Venzon, Justin E. Sausville, Lynn Sorbara, Rita Salloum
Publikováno v:
American Journal of Clinical Pathology. 119:213-217
We studied 86 specimens from 24 patients with hairy cell leukemia (HCL) to determine the sensitivity of routine flow cytometry (FC) and consensus primer PCR (cpPCR) in this disease. FC was more sensitive, detecting HCL in 48 (56%) of 86 specimens, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5489e4f1d57f519beb62425786a07c0
https://doi.org/10.1309/g6299513nglcub1k
https://doi.org/10.1309/g6299513nglcub1k
Autor:
J B, Sunwoo, Z, Chen, G, Dong, N, Yeh, C, Crowl Bancroft, E, Sausville, J, Adams, P, Elliott, C, Van Waes
Publikováno v:
Clinical Cancer Research. 21:942-943
We have shown that activation of nuclear factor-kappa B (NF-kappa B) promotes cell survival and expression of cytokines such as growth-regulated oncogene-alpha, which can modulate angiogenesis, growth, and metastasis of squamous cell carcinoma (SCC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58be529fc7063d34b9d4d89a80853220
https://doi.org/10.1158/1078-0432.ccr-14-2550
https://doi.org/10.1158/1078-0432.ccr-14-2550
Autor:
P J Worland, W.F. De Azevedo, H J Mueller-Dieckmann, Sung-Hou Kim, E Sausville, Ursula Schulze-Gahmen
Publikováno v:
Proceedings of the National Academy of Sciences. 93:2735-2740
The central role of cyclin-dependent kinases (CDKs) in cell cycle regulation makes them a promising target for studying inhibitory molecules that can modify the degree of cell proliferation. The discovery of specific inhibitors of CDKs such as polyhy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1424399b0d50cc5d4e9f987d4f1f48cf
https://doi.org/10.1073/pnas.93.7.2735
https://doi.org/10.1073/pnas.93.7.2735
Autor:
Justin E, Sausville, Rita G, Salloum, Lynn, Sorbara, Douglas W, Kingma, Mark, Raffeld, Robert J, Kreitman, Paula D, Imus, David, Venzon, Maryalice, Stetler-Stevenson
Publikováno v:
American journal of clinical pathology. 119(2)
We studied 86 specimens from 24 patients with hairy cell leukemia (HCL) to determine the sensitivity of routine flow cytometry (FC) and consensus primer PCR (cpPCR) in this disease. FC was more sensitive, detecting HCL in 48 (56%) of 86 specimens, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24a420faa1181454cb258503e3fbfce8
https://pubmed.ncbi.nlm.nih.gov/12579991
https://pubmed.ncbi.nlm.nih.gov/12579991
Autor:
Pradip Amin, James W. Snider, William F. Regine, E. Sausville, Nader Hanna, M.E. Francis, H.R. Alexander
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 90:S767
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be2289b35d79bc2d7af83da9ecb032a8
https://doi.org/10.1016/j.ijrobp.2014.05.2220
https://doi.org/10.1016/j.ijrobp.2014.05.2220
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(2)
A retrospective analysis of 102 patients with relapsed, non-Hodgkin's lymphoma treated with two different ricin A chain-containing immunotoxins (ITs) in five Phase I clinical trials indicates that the dose-limiting toxicity, vascular leak syndrome, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b26d3c287ffbd7941f6a1f491554d472
https://pubmed.ncbi.nlm.nih.gov/11234876
https://pubmed.ncbi.nlm.nih.gov/11234876
Publikováno v:
Biomedical chromatography : BMC. 14(5)
UCN-01, 7-hydroxystaurosporine, is an antagonist of protein kinase C, as well as causing cell cycle arrest. We developed and validated an HPLC assay method for the quantitation of UCN-01. Plasma and saliva standard curves were prepared at concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a39089652b89c445777cfe6414b8679
https://pubmed.ncbi.nlm.nih.gov/10960835
https://pubmed.ncbi.nlm.nih.gov/10960835
Autor:
W H, Wilson, L, Sorbara, W D, Figg, E K, Mont, E, Sausville, K E, Warren, F M, Balis, K, Bauer, M, Raffeld, A M, Senderowicz, A, Monks
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(2)
Emerging evidence suggests that apoptosis is an important mechanism of tumor cell death from antineoplastic therapy. 7-hydroxystaurosporine (UCN-01) is a novel protein kinase inhibitor that increases chemotherapy-induced apoptosis in vitro and is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c2de14f510e2c6e65bf8aa5f196d838
https://pubmed.ncbi.nlm.nih.gov/10690518
https://pubmed.ncbi.nlm.nih.gov/10690518