Zobrazeno 1 - 10
of 395
pro vyhledávání: '"E, Rokita"'
Publikováno v:
Biochemistry. 62:1298-1306
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d91522b6b24c969b5a0f47d94a6166d6
https://doi.org/10.1021/acs.biochem.3c00041
https://doi.org/10.1021/acs.biochem.3c00041
Publikováno v:
Nucleic Acids Research.
Photochemical dimerization of adjacent pyrimidines is fundamental to the creation of mutagenic hotspots caused by ultraviolet light. Distribution of the resulting lesions (cyclobutane pyrimidine dimers, CPDs) is already known to be highly variable in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b878a4ae60ec50ea43ecfc69774ff1
https://doi.org/10.1093/nar/gkad434
https://doi.org/10.1093/nar/gkad434
Akademický článek
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Autor:
Theodore E. Rokita
Publikováno v:
Indiana Law Review. 55:1-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c4fa65f61481fe83c4f4590ca8a274d
https://doi.org/10.18060/26415
https://doi.org/10.18060/26415
Autor:
Jonathan M. Musila, Steven E. Rokita
Publikováno v:
Biochemistry
Consensus sequences have the potential to help classify the structure and function of proteins and highlight key regions that may contribute to their biological properties. Often, the level of significance will track with the extent of sequence conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc505d79ad16e32ab92c851cc93f2407
https://doi.org/10.1021/acs.biochem.2c00037
https://doi.org/10.1021/acs.biochem.2c00037
Publikováno v:
Bioconjug Chem
Polyamine and polyammonium ion conjugates are often used to direct reagents to nucleic acids based on their strong electrostatic attraction to the phosphoribose backbone. Such non-specific interactions do not typically alter the specificity of the at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57274a7096a0e302ff9eb422fc421933
https://doi.org/10.1021/acs.bioconjchem.0c00166
https://doi.org/10.1021/acs.bioconjchem.0c00166
Publikováno v:
The Journal of Biological Chemistry
The nitroreductase superfamily of enzymes encompasses many flavin mononucleotide (FMN)-dependent catalysts promoting a wide range of reactions. All share a common core consisting of an FMN-binding domain, and individual subgroups additionally contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be79555d175b00f23fd0c65fac08e16c
https://pubmed.ncbi.nlm.nih.gov/34748729
https://pubmed.ncbi.nlm.nih.gov/34748729
Autor:
Steven E. Rokita, Blessing D. Deeyaa
Publikováno v:
Organic & Biomolecular Chemistry. 18:1671-1678
The dynamic nature of nucleic acid alkylation by simple ortho quinone methides (QM) and their conjugates has provided numerous opportunities ranging from sequence selective targeting to bipedal walking in duplex DNA. To enhance the diffusion rate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14bc38148a25782c2617849794fa6ba
https://doi.org/10.1039/d0ob00081g
https://doi.org/10.1039/d0ob00081g
Autor:
Steven E. Rokita, Shane R. Byrne
Publikováno v:
Chem Res Toxicol
The reversible generation and capture of certain electrophilic quinone methide intermediates support dynamic reactions with DNA that allow for migration and transfer of alkylation and cross-linking. This reversibility also expands the possible conseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8191e388773dc3153ad7f1067d8f6b38
https://pubmed.ncbi.nlm.nih.gov/33147957
https://pubmed.ncbi.nlm.nih.gov/33147957
Autor:
Steven E. Rokita, Zuodong Sun
Publikováno v:
ACS Catalysis. 8:11783-11793
Reductive dehalogenation offers an attractive approach for removing halogenated pollutants from the environment, and iodotyrosine deiodinase (IYD) may contribute to this process after it can be eng...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fdfa99db5f7245a4f2adb2dd14e998a
https://doi.org/10.1021/acscatal.8b03587
https://doi.org/10.1021/acscatal.8b03587