Determination of a vancomycin nephrotoxicity threshold and assessment of target attainment in hematology patients

Autor: Sherilyn Wong, Philip R. Selby, Stephanie E. Reuter

Publikováno v: Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)

Abstract An area‐under‐the‐curve (AUC24)‐based approach is recommended to guide vancomycin therapeutic drug monitoring (TDM), yet trough concentrations are still commonly used despite associated risks. A definitive toxicity target is lacking,

Externí odkaz: https://doaj.org/article/da66388afe6448bb9fd5c611aad57617

Tropical field stations yield high conservation return on investment

Autor: Timothy M. Eppley, Kim E. Reuter, Timothy M. Sefczek, Jen Tinsman, Luca Santini, Selwyn Hoeks, Seheno Andriantsaralaza, Sam Shanee, Anthony Di Fiore, Joanna M. Setchell, Karen B. Strier, Peter A. Abanyam, Aini Hasanah Abd Mutalib, Ekwoge Abwe, Tanvir Ahmed, Marc Ancrenaz, Raphali R. Andriantsimanarilafy, Andie Ang, Filippo Aureli, Louise Barrett, Jacinta C. Beehner, Marcela E. Benítez, Bruna M. Bezerra, Júlio César Bicca‐Marques, Dominique Bikaba, Robert Bitariho, Christophe Boesch, Laura M. Bolt, Ramesh Boonratana, Thomas M. Butynski, Gustavo R. Canale, Susana Carvalho, Colin A. Chapman, Dilip Chetry, Susan M. Cheyne, Marina Cords, Fanny M. Cornejo, Liliana Cortés‐Ortiz, Camille N. Z. Coudrat, Margaret C. Crofoot, Drew T. Cronin, Alvine Dadjo, S. Chrystelle Dakpogan, Emmanuel Danquah, Tim R. B. Davenport, Yvonne A. deJong, Stella de laTorre, Andrea Dempsey, Judeline C. Dimalibot, Rainer Dolch, Giuseppe Donati, Alejandro Estrada, Rassina A. Farassi, Peter J. Fashing, Eduardo Fernandez‐Duque, Maria J. Ferreira da Silva, Julia Fischer, César F. Flores‐Negrón, Barbara Fruth, Terence Fuh Neba, Lief Erikson Gamalo, Jörg U. Ganzhorn, Paul A. Garber, Smitha D. Gnanaolivu, Mary Katherine Gonder, Sery Ernest Gonedelé Bi, Benoit Goossens, Marcelo Gordo, Juan M. Guayasamin, Diana C. Guzmán‐Caro, Andrew R. Halloran, Jessica A. Hartel, Eckhard W. Heymann, Russell A. Hill, Kimberley J. Hockings, Gottfried Hohmann, Naven Hon, Mariano G. Houngbédji, Michael A. Huffman, Rachel A. Ikemeh, Inaoyom Imong, Mitchell T. Irwin, Patrícia Izar, Leandro Jerusalinsky, Gladys Kalema‐Zikusoka, Beth A. Kaplin, Peter M. Kappeler, Stanislaus M. Kivai, Cheryl D. Knott, Intanon Kolasartsanee, Kathelijne Koops, Martin M. Kowalewski, Deo Kujirakwinja, Ajith Kumar, Quyet K. Le, Rebecca J. Lewis, Aung Ko Lin, Andrés Link, Luz I. Loría, Menladi M. Lormie, Edward E. Louis Jr., Ngwe Lwin, Fiona Maisels, Suchinda Malaivijitnond, Lesley Marisa, Gráinne M. McCabe, W. Scott McGraw, Addisu Mekonnen, Pedro G. Méndez‐Carvajal, Tânia Minhós, David M. Montgomery, Citlalli Morelos‐Juárez, Bethan J. Morgan, David Morgan, Amancio Motove Etingüe, Papa Ibnou Ndiaye, K. Anne‐Isola Nekaris, Nga Nguyen, Vincent Nijman, Radar Nishuli, Marilyn A. Norconk, Luciana I. Oklander, Rahayu Oktaviani, Julia Ostner, Emily Otali, Susan E. Perry, Eduardo J. Pinel Ramos, Leila M. Porter, Jill D. Pruetz, Anne E. Pusey, Helder L. Queiroz, Mónica A. Ramírez, Guy Hermas Randriatahina, Hoby Rasoanaivo, Jonah Ratsimbazafy, Joelisoa Ratsirarson, Josia Razafindramanana, Onja H. Razafindratsima, Vernon Reynolds, Rizaldi Rizaldi, Martha M. Robbins, Melissa E. Rodríguez, Marleny Rosales‐Meda, Crickette M. Sanz, Dipto Sarkar, Anne Savage, Amy L. Schreier, Oliver Schülke, Gabriel H. Segniagbeto, Juan Carlos Serio‐Silva, Arif Setiawan, John Seyjagat, Felipe E. Silva, Elizabeth M. Sinclair, Rebecca L. Smith, Denise Spaan, Fiona A. Stewart, Shirley C. Strum, Martin Surbeck, Magdalena S. Svensson, Mauricio Talebi, Luc Roscelin Tédonzong, Bernardo Urbani, João Valsecchi, Natalie Vasey, Erin R. Vogel, Robert B. Wallace, Janette Wallis, Siân Waters, Roman M. Wittig, Richard W. Wrangham, Patricia C. Wright, Russell A. Mittermeier

Publikováno v: Conservation Letters, Vol 17, Iss 2, Pp n/a-n/a (2024)

Abstract Conservation funding is currently limited; cost‐effective conservation solutions are essential. We suggest that the thousands of field stations worldwide can play key roles at the frontline of biodiversity conservation and have high intrin

Externí odkaz: https://doaj.org/article/f5f66dc3fe1649729ac694a737d44561

FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation

Autor: Joshua I. Warrick, Wenhuo Hu, Hironobu Yamashita, Vonn Walter, Lauren Shuman, Jenna M. Craig, Lan L. Gellert, Mauro A. A. Castro, A. Gordon Robertson, Fengshen Kuo, Irina Ostrovnaya, Judy Sarungbam, Ying-bei Chen, Anuradha Gopalan, Sahussapont J. Sirintrapun, Samson W. Fine, Satish K. Tickoo, Kwanghee Kim, Jasmine Thomas, Nagar Karan, Sizhi Paul Gao, Timothy N. Clinton, Andrew T. Lenis, Timothy A. Chan, Zhiyu Chen, Manisha Rao, Travis J. Hollman, Yanyun Li, Nicholas D. Socci, Shweta Chavan, Agnes Viale, Neeman Mohibullah, Bernard H. Bochner, Eugene J. Pietzak, Min Yuen Teo, Gopa Iyer, Jonathan E. Rosenberg, Dean F. Bajorin, Matthew Kaag, Suzanne B. Merrill, Monika Joshi, Rosalyn Adam, John A. Taylor, Peter E. Clark, Jay D. Raman, Victor E. Reuter, Yu Chen, Samuel A. Funt, David B. Solit, David J. DeGraff, Hikmat A. Al-Ahmadie

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)

Bladder cancer can often exhibit genomic and morphological heterogeneity. Here, the authors use genomics analysis to show lineage plasticity of bladder cancers with squamous differentiation, and identify key transcription factors related to this morp

Externí odkaz: https://doaj.org/article/626d86eebf314e6e8d115afe8bbcc1dd

An update on computational pathology tools for genitourinary pathology practice: A review paper from the Genitourinary Pathology Society (GUPS)

Autor: Anil V. Parwani, Ankush Patel, Ming Zhou, John C. Cheville, Hamid Tizhoosh, Peter Humphrey, Victor E. Reuter, Lawrence D. True

Publikováno v: Journal of Pathology Informatics, Vol 14, Iss , Pp 100177- (2023)

Machine learning has been leveraged for image analysis applications throughout a multitude of subspecialties. This position paper provides a perspective on the evolutionary trajectory of practical deep learning tools for genitourinary pathology throu

Externí odkaz: https://doaj.org/article/0323aad2f3e8453d82ac37606b822825

Detection of Ganciclovir-Resistant Cytomegalovirus in a Prospective Cohort of Kidney Transplant Recipients Receiving Subtherapeutic Valganciclovir Prophylaxis

Autor: Diana D. Wong, Wendy J. van Zuylen, Talia Novos, Sophie Stocker, Stephanie E. Reuter, Jane Au, Charles S. P. Foster, Richard O. Day, Andrea R. Horvath, Zoltan Endre, William D. Rawlinson

Publikováno v: Microbiology Spectrum, Vol 10, Iss 3 (2022)

ABSTRACT Cytomegalovirus infection during antiviral prophylaxis occurs in transplant recipients despite individualized regimens based on renal function. Fifty kidney transplant recipients were assessed between 2016 and 2019 for valganciclovir dosing,

Externí odkaz: https://doaj.org/article/6a9b3fae9fb94faca5b49f5cc5ce3175