Zobrazeno 1 - 10
of 275
pro vyhledávání: '"E, Raines"'
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 13 (2022)
Cushing’s syndrome (CS) is an endocrine disease characterized by excessive adrenocortical steroid production. One of the mainstay pharmacological treatments for CS are steroidogenesis enzyme inhibitors, including the antifungal agent ketoconazole a
Externí odkaz:
https://doaj.org/article/2c9b5a67afdd4a04b2cc3dc47bd2e49a
Publikováno v:
BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significan
Externí odkaz:
https://doaj.org/article/5c144b9f84a44fd3bcd8d38c981736b2
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 383:238-245
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b962371f935cdba94f325a744f45952
https://doi.org/10.1124/jpet.122.001337
https://doi.org/10.1124/jpet.122.001337
Publikováno v:
British Journal of Pharmacology. 178:4842-4858
Background and purpose In addition to binding to the classical high-affinity extracellular benzodiazepine binding site of the GABAA receptor, some benzodiazepines occupy transmembrane inter-subunit anesthetic sites that bind etomidate (β+ /α- sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f7f0fb10f1806b2ccf95de8f9618c6
https://doi.org/10.1111/bph.15662
https://doi.org/10.1111/bph.15662
Autor:
Selwyn S. Jayakar, Xiaojuan Zhou, Helen Hoyt, Douglas E. Raines, Keith W. Miller, Andrea Pence, Jonathan B. Cohen, Megan McGrath, Stuart A. Forman
Publikováno v:
Anesthesiology. 133:583-594
Background Recent cryo-electron microscopic imaging studies have shown that in addition to binding to the classical extracellular benzodiazepine binding site of the α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor, diazepam also binds to etomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d88bd25a7389031e1d35942a5455b873
https://doi.org/10.1097/aln.0000000000003403
https://doi.org/10.1097/aln.0000000000003403
Autor:
Adam A. Dalia, Douglas E. Raines
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 35:1086-1088
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5490f66fb7681681eb697a01c57bbb3b
https://doi.org/10.1053/j.jvca.2021.01.034
https://doi.org/10.1053/j.jvca.2021.01.034
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: In addition to binding to the classical high-affinity extracellular benzodiazepine binding site of the GABA(A) receptor, some benzodiazepines occupy transmembrane inter-subunit anaesthetic sites that bind etomidate (β(+)/α(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9faaf6d30cea06d6fd6759ee1daecd60
https://pubmed.ncbi.nlm.nih.gov/34386973
https://pubmed.ncbi.nlm.nih.gov/34386973
Autor:
Brian E. Raines, Jonathan Meddaugh
Publikováno v:
Journal of Mathematical Analysis and Applications. 479:1355-1363
In this paper we compute the topological entropy and we consider the question of ω-chaos for shift spaces over countable alphabets. We show that if a shift space has the weak specification property, then it has ω-chaos, and we show that if, in addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83361e16d29de2decd8932732fe32f57
https://doi.org/10.1016/j.jmaa.2019.07.001
https://doi.org/10.1016/j.jmaa.2019.07.001
Autor:
Dario Lehoux, Megan McGrath, Brad Zerler, Douglas E. Raines, Beatrijs I. Valk, John J. A. Marota
Publikováno v:
Anesthesiology, 131(2), 287-304. LIPPINCOTT WILLIAMS & WILKINS
Editor's PerspectiveWhat We Already Know about This Topic The investigational etomidate analog ABP-700 causes involuntary muscle movements in humans at anesthetic doses and seizures in dogs at 10-fold higher toxicologic doses The mechanism of seizure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bad0378de25fc0ed4b4edf431ac4f8
https://doi.org/10.1097/aln.0000000000002758
https://doi.org/10.1097/aln.0000000000002758
Publikováno v:
Discrete & Continuous Dynamical Systems - S. 12:2211-2220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ddfa554e2afa7d395c54ae654250efd
https://doi.org/10.3934/dcdss.2019142
https://doi.org/10.3934/dcdss.2019142