Bacillus subtilis genome project: cloning and sequencing of the 97 kb region from 325° to 333deg

Autor: M.-P. Coudart, Margarida Santana, Georges Rapoport, J. Schwelzer, I. Moszer, Luisa A. Marcelino, E. Presecan, Maryvonne Arnaud, Antoine Danchin, Marie-Françoise Hullo, E. Schneider, B. Lubochinsicy, W. Gonzales, A. Vertes, F. Kunst, M S Ionescu, Philippe Glaser

Publikováno v: Molecular microbiology. 10(2)

In the framework of the European project aimed at the sequencing of the Bacillus subtilis genome the DNA region located between gerB (314 degrees) and sacXY (333 degrees) was assigned to the Institut Pasteur. In this paper we describe the cloning and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a386f04defeea3a3f50624d340e21c84
https://pubmed.ncbi.nlm.nih.gov/28776854

Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4

Autor: E, Hustert, A, Zibat, E, Presecan-Siedel, R, Eiselt, R, Mueller, C, Fuss, I, Brehm, U, Brinkmann, M, Eichelbaum, L, Wojnowski, O, Burk

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 29(11)

Between 45 and 60% of all drugs currently used are metabolized by the CYP3A4 protein. CYP3A4 expression in liver varies up to 60-fold in the general population, which can lead to ineffective drug therapy (high CYP3A4) or, on the other hand, to harmfu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::856f14b376ee40806416d03b27cf3671
https://pubmed.ncbi.nlm.nih.gov/11602521

The complete genome sequence of the gram-positive bacterium Bacillus subtilis

Autor: Daniel Portetelle, Angelo Tognoni, Vladimir Lazarevic, Hiroshi Yoshikawa, Carlo V. Bruschi, A. Düsterhöft, H. Wedler, J.-J. Codani, S. C. Brignell, Masaya Fujita, B. Roche, Motoki Mizuno, Junichi Sekiguchi, P. Koetter, Miyuki Kumano, K. Yoshida, Richard A. Daniel, Alain Brans, Y. Kobayashi, Jeff Errington, B.-S. Shin, BJ Guy, Simone J. Séror, Peter Terpstra, S. Fuma, Y. Kasahara, Mary O'Reilly, F Scoffone, Claudine Médigue, R. Wambutt, Matthias Rose, G. Koningstein, Nathalie Galleron, M. G. Bertero, M. Klaerr-Blanchard, Bernard Joris, B. Oudega, Michael A. Rieger, G. Alloni, Mitsuhiro Itaya, Simon Ming-Yuen Lee, Bénédicte Purnelle, Steffen Porwollik, Marie-Françoise Hullo, Alla Lapidus, Valentina Tosato, Colin R. Harwood, N. Medina, Catherine Mauël, Kevin M. Devine, Kanako Kurita, Ken-Ichi Takemaru, Nicola J. Cummings, Susanne Krogh, Louis M. Jones, Micheline Vandenbol, Rainer Borriss, K. Ogawa, Alain Levine, E. Presecan, Bolotin Ap, E. Scanlan, Hisashi Yoshikawa, Michio Takeuchi, G. Guiseppi, J. Lauber, Stanislav Dusko Ehrlich, Ivan Moszer, D. Moestl, K. Yasumoto, S. Schleich, S. Hosono, E. Tacconi, E. Wedler, Georges Rapoport, E. J. Golightly, Sierd Bron, T. Takagi, Shigeki Uchiyama, C. Fabret, Kazuko Haga, Alexei Sorokin, L. Boursier, Pascale Serror, Vasco Azevedo, Guido Grandi, Petar Pujic, A. M. Prescott, Sa Youl Ghim, A. Ogiwara, François Denizot, Hiroki Yamamoto, Blazenka Soldo, R. Schroeter, S. Masuda, S. Brouillet, André Goffeau, Agnieszka Sekowska, A. Tamakoshi, Naotake Ogasawara, Alain Viari, Eugenio Ferrari, V. Capuano, Eduardo P. C. Rocha, Dimitri Karamata, S. Lardinois, D. Foulger, Michiel A. Noback, Ian F. Connerton, Katsunori Yata, Victor Parro, Alessandra M. Albertini, Alain Hénaut, Carsten Klein, C. Fritz, Toshitada Sato, P. Winters, Alessandro Galizzi, Yoshito Sadaie, Stacey Reynolds, H. Liu, Hideyuki Takahashi, Tetsu Tanaka, David Noone, S. Borchert, S. Nakai, T. Weitzenegger, Kunio Yamane, F. Kunst, S.-H. Park, P. T. Emmerson, M. Braun, Emmanuelle Zumstein, Yasutaro Fujita, Philippe Bessières, Noel Carter, Antoine Danchin, A. Vassarotti, B. Caldwell, M. Rey, Françoise Vannier, Carlo Rivolta, Thomas Pohl, Rafael P. Mellado, H. Hilbert, K. D. Entian, Jacques Haiech, Siger Holsappel, Soo Keun Choi, Philippe Glaser, Anil Wipat

Publikováno v: Nature, 390(6657), 249-256. Nature Publishing Group

Bacillus subtilis is the best-characterized member of the Gram-positive bacteria. Its genome of 4,214,810 base pairs comprises 4,100 protein-coding genes. Of these protein-coding genes, 53% are represented once, while a quarter of the genome correspo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28662a0d348fc818e176c02df2917367
https://pubmed.ncbi.nlm.nih.gov/9384371

Structural and catalytic properties of L-alanine dehydrogenase from Bacillus cereus

Autor: H, Porumb, D, Vancea, L, Mureşan, E, Presecan, I, Lascu, I, Petrescu, T, Porumb, R, Pop, O, Bârzu

Publikováno v: The Journal of biological chemistry. 262(10)

Alanine dehydrogenase from Bacillus cereus, a non-allosteric enzyme composed of six identical subunits, was purified to homogeneity by chromatography on blue-Sepharose and Sepharose 6B-CL. Like other pyridine-linked dehydrogenases, alanine dehydrogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b972b01541544bdf2a3b69bc3b5b18fd
https://pubmed.ncbi.nlm.nih.gov/3104322

Bacillus subtilis as a host for natural product discovery and engineering of biosynthetic gene clusters.

Autor: Put, Hanne, Gerstmans, Hans, Vande Capelle, Hanne, Fauvart, Maarten, Michiels, Jan, Masschelein, Joleen

Publikováno v: Natural Product Reports; Jul2024, Vol. 41 Issue 7, p1113-1151, 39p