Zobrazeno 1 - 10
of 93
pro vyhledávání: '"E, Parganas"'
Autor:
S Asano, N Kamada, Jun Yokota, S Takahashi, E Parganas, Kazumi Suzukawa, K Tani, H Asou, A Gajjar, Tatsuo Abe
Publikováno v:
Europe PubMed Central
Structural alterations occur in the long arm of chromosome 3 in approximately 2% of patients with acute myelogenous leukemia (AML) or myelodysplastic syndrome (MDS). The major alterations are inv(3)(q21q26) and t(3:3)(q21;q26) and are often classifie
Autor:
L James, ER Levy, E Parganas, K Morishita, S Gisselbrecht, JN Ihle, Veronica J. Buckle, D Oscier, S Fichelson
Publikováno v:
Blood. 83:1348-1354
Specific rearrangements involving 3q21 and 3q26 are well documented in acute myeloid leukemia (AML). Aberrant expression of the Ecotropic virus integration-1 (EVI1) gene, located at 3q26, has been reported in individuals with AML and translocations o
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Publikováno v:
Molecular and Cellular Biology. 12:183-189
Expression of the Evi-1 gene is frequently activated in murine myeloid leukemias by retroviral insertions immediately 5' or 90 kb 5' of the gene. The Evi-1 gene product is a nuclear, DNA-binding zinc finger protein of 145 kDa. On the basis of the pro
Autor:
J N, Ihle, W, Thierfelder, S, Teglund, D, Stravopodis, D, Stravapodis, D, Wang, J, Feng, E, Parganas
Publikováno v:
Annals of the New York Academy of Sciences. 865
A variety of cytokines that regulate functions of multiple lineages share the utilization of receptors that are structurally and functionally related and are referred to as the cytokine receptor superfamily. These receptors associate with one or more
Publikováno v:
The cancer journal from Scientific American. 4
Publikováno v:
Blood. 85(3)
Autor:
E R, Levy, E, Parganas, K, Morishita, S, Fichelson, L, James, D, Oscier, S, Gisselbrecht, J N, Ihle, V J, Buckle
Publikováno v:
Blood. 83(5)
Specific rearrangements involving 3q21 and 3q26 are well documented in acute myeloid leukemia (AML). Aberrant expression of the Ecotropic virus integration-1 (EVI1) gene, located at 3q26, has been reported in individuals with AML and translocations o
Publikováno v:
Oncogene. 5(9)
Activation of the Evi-1 zinc finger gene is commonly associated with the transformation of murine leukemias and is involved in some cases of human AML involving rearrangements at chromosome 3q25. To determine the normal function of the gene, we have
Autor:
K, Morishita, E, Parganas, C, Bartholomew, N, Sacchi, M B, Valentine, S C, Raimondi, M M, Le Beau, J N, Ihle
Publikováno v:
Oncogene research. 5(3)
The murine Evi-1 gene encodes a protein that has multiple 28-amino acid repeats containing the consensus sequence found in the zinc finger domains of many transcriptional regulatory proteins. Activation of the expression of the Evi-1 gene is frequent