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Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995

Autor: W.-D. Ludwig, A. Reiter, E. Odenwald, Martin Zimmermann, Helmut Gadner, Hansjörg Riehm, Günter Henze, Martin Schrappe, Jochen Harbott

Publikováno v: Leukemia. 14:2205-2222

Four thousand, four hundred and forty eligible children of up to 18 years of age were treated in four consecutive trials between 1981 and 1995 with the treatment protocols of the Berlin-Frankfurt-Munster (BFM) study group for childhood acute lymphobl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d157312459943bca80b3403e456d933
https://doi.org/10.1038/sj.leu.2401973

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Prediction of outcome by early response in childhood acute lymphoblastic leukemia

Autor: M. Lauten, Anja Möricke, Rita Beier, Martin Zimmermann, E. Odenwald, Andishe Attarbaschi, Martin Schrappe, Martin Stanulla, Felix Niggli

BACKGROUND: In the ALL-BFM studies for treatment of acute lymphoblastic leukemia, reduction of leukemic blasts in peripheral blood after a one-week prednisone pre-phase - the so-called prednisone response - has been used for risk stratification since

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8cc590e15df261351dd531bd867244
https://www.zora.uzh.ch/id/eprint/84396/

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Prediction of outcome by early bone marrow response in childhood acute lymphoblastic leukemia treated in the ALL-BFM 95 trial: differential effects in precursor B-cell and T-cell leukemia

Autor: Melchior Lauten, Charlotte M. Niemeyer, E. Odenwald, Andishe Attarbaschi, Martin Zimmermann, Barbara Meissner, Rita Beier, Martin Stanulla, Felix Niggli, Hansjörg Riehm, Martin Schrappe, Anja Möricke

Publikováno v: Haematologica. 97(7)

BACKGROUND: In the ALL-BFM 95 trial for treatment of acute lymphoblastic leukemia, response to a prednisone pre-phase (prednisone response) was used for risk stratification in combination with age and white blood cell count at diagnosis, response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8612bf9973547dbb5ecd92dd96a4b60
https://pubmed.ncbi.nlm.nih.gov/22271901

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Therapiestudie NHL-BFM 90 zur Behandlung maligner Non-Hodgkin-Lymphome bei Kindern und Jugendlichen - Teil 1: Klassifikation und Einteilung in strategische Therapiegruppen

Autor: W.-D. Ludwig, Dietrich Henzler, E. Odenwald, H.-H. Wacker, Reza Parwaresch, M. Tiemann, H. Riehm, Elif Yakisan, Alfred Reiter, Martin Schrappe, Karl-Walter Sykora, A. Brandt

Publikováno v: Klinische Pädiatrie. 206:222-233

One of the goals of the study NHL-BFM 90 was to investigate the distribution and prognosis of the different subtypes of Non-Hodgkin's Lymphoma (NHL) in children and adolescents according to histological, cytomorphological and immunological characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3e9e6a33acf66dc48659396b64b7935
https://doi.org/10.1055/s-2008-1046608

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Konzeption und Zwischenergebnis der Therapiestudie ALL-BFM 90 zur Behandlung der akuten lymphoblastischen Leukämie bei Kindern und Jugendlichen: Die Bedeutung des initialen Therapieansprechens in Blut und Knochenmark

Publikováno v: Klinische Pädiatrie. 206:208-221

In the ongoing trial ALL-BFM 90 for the treatment of childhood non-B cell acute lymphoblastic leukemia (ALL) 1468 unselected patients (pts) were enrolled from 84 centers in Germany and Switzerland from 4/90 to 12/93. Based on the results of the previ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7938bdd4baeb3b6668205be77f2ac1bb
https://doi.org/10.1055/s-2008-1046607

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Inzidenz, klinische Merkmale und prognostische Bedeutung immunologischer Subtypen der akuten lymphoblastischen Leukämie (ALL) im Kindesalter: Erfahrungen der Therapiestudien ALL-BFM 83 und 86

Autor: E. Odenwald, C Sperling, J V Teichmann, W.-D. Ludwig, H. Riehm, A. Reiter, J. Ritter, B. Komischke, S Sauter

Publikováno v: Klinische Pädiatrie. 202:243-252

In the therapy studies ALL-BFM 83 and 86, immunophenotyping of ALL by monoclonal antibodies was performed in a total of 1162 protocol patients (ALL-BFM 83 n = 578; ALL-BFM 86 n = 584). Both studies yielded similar results with respect to the incidenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1eed614ae65e563db79a880c4b8dfcbe
https://doi.org/10.1055/s-2007-1025528

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Differential effects of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in children with severe congenital neutropenia

Autor: Wolfgang Müller, Alfred Reiter, Lawrence Souza, Cornelia Zeidler, E. Odenwald, Karl Welte, Hansjörg Riehm

Publikováno v: Blood. 75:1056-1063

Severe congenital neutropenia (SCN) is a disorder of myelopoiesis characterized by severe neutropenia secondary to a maturational arrest at the level of promyelocytes. We treated five patients with SCN with recombinant human granulocyte-macrophage co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9055acab8b1fa070ab92c7a3370126
https://doi.org/10.1182/blood.v75.5.1056.1056

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Prognostic impact of age in children and adolescents with acute lymphoblastic leukemia: data from the trials ALL-BFM 86, 90, and 95

Autor: W.-D. Ludwig, H. Riehm, Martin Schrappe, E. Odenwald, Anja Möricke, Martin Zimmermann, Helmut Gadner, A. Reiter, Jochen Harbott

Publikováno v: Klinische Padiatrie. 217(6)

Large progress has been made in the treatment of acute lymphoblastic leukemia (ALL) of childhood and adolescence over the past 30 years. Eighty percent of the patients can be cured, but clinical subgroups with a dismal outcome can still be identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85eabc460a377ec27ddfbdba650eb70
https://pubmed.ncbi.nlm.nih.gov/16307416

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Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Münster

Autor: M, Schrappe, A, Reiter, M, Zimmermann, J, Harbott, W D, Ludwig, G, Henze, H, Gadner, E, Odenwald, H, Riehm

Publikováno v: Leukemia. 14(12)

Four thousand, four hundred and forty eligible children of up to 18 years of age were treated in four consecutive trials between 1981 and 1995 with the treatment protocols of the Berlin-Frankfurt-Münster (BFM) study group for childhood acute lymphob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ae02a6699d444fd3fdf1d6f6a47d7e4
https://pubmed.ncbi.nlm.nih.gov/11187912

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