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Akademický článek

Engaging Communities in Emerging Infectious Disease Mitigation to Improve Public Health and Safety

Autor: Michàlle E. Mor Barak, Shinyi Wu, Gil Luria, Leslie P. Schnyder, Ruotong Liu, Anthony Nguyen, Charles D. Kaplan

Publikováno v: Emerging Infectious Diseases, Vol 30, Iss 7, Pp 1390-1397 (2024)

The COVID-19 pandemic highlighted the need for potent community-based tools to improve preparedness. We developed a community health-safety climate (HSC) measure to assess readiness to adopt health behaviors during a pandemic. We conducted a mixed-me

Externí odkaz: https://doaj.org/article/17dc80b819314f10a4ea8db5fbc76ce6

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Akademický článek

Engaging Communities in Emerging Infectious Disease Mitigation to Improve Public Health and Safety.

Autor: Barak, Michàlle E. Mor^1,2, Shinyi Wu^2,3, Luria, Gil⁴, Schnyder, Leslie P.², Liu, Ruotong², Nguyen, Anthony³, Kaplan, Charles D.⁴

Publikováno v: Emerging Infectious Diseases. Jul2024, Vol. 30 Issue 7, p1390-1397. 8p.

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Akademický článek

GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease

Autor: Lauren M. McIntyre, Francisco Huertas, Alison M. Morse, Rachel Kaletsky, Coleen T. Murphy, Vrinda Kalia, Gary W. Miller, Olexander Moskalenko, Ana Conesa, Danielle E. Mor

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)

Abstract Parkinson’s disease (PD) is a disabling neurodegenerative disorder in which multiple cell types, including dopaminergic and cholinergic neurons, are affected. The mechanisms of neurodegeneration in PD are not fully understood, limiting the

Externí odkaz: https://doaj.org/article/7b6b9565a6ca4caa885a23452e6ff4cd

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Akademický článek

High-throughput behavioral screen in C. elegans reveals Parkinson’s disease drug candidates

Autor: Salman Sohrabi, Danielle E. Mor, Rachel Kaletsky, William Keyes, Coleen T. Murphy

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)

Salman Sohrabi et al. develop an automated, high-throughput assay to study spasm-like curling behavior in C. elegans, which is related to motor control symptoms in Parkinson’s disease. They apply this screening approach to identify four candidate d

Externí odkaz: https://doaj.org/article/74da37c3af4d4181ad273528c6947316

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Akademický článek

Mitochondrial hyperactivity as a potential therapeutic target in Parkinson’s disease

Autor: Danielle E. Mor, Coleen T. Murphy

Publikováno v: Translational Medicine of Aging, Vol 4, Iss , Pp 117-120 (2020)

Mitochondrial dysfunction is thought to contribute to neurodegeneration in Parkinson’s disease (PD), yet the cellular events that lead to mitochondrial disruption remain unclear. Post-mortem studies of PD patient brains and the use of complex I inh

Externí odkaz: https://doaj.org/article/1d27ec0f02154eada7f13f1344fd218f

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