Výsledky vyhledávání - "E, McLoughlin"

Akademický článek

Lessons Learned From Shared Decision-Making With Oral Anticoagulants: Viewpoint on Suggestions for the Development of Oral Chemotherapy Decision Aids

Autor: Daniel E McLoughlin, Fabiola M Moreno Echevarria, Sherif M Badawy

Publikováno v: JMIR Cancer, Vol 10, p e56935 (2024)

Oral chemotherapy is commonly prescribed, and by using decision aids (DAs), clinicians can facilitate shared decision-making (SDM) to align treatment choices with patient goals and values. Although products exist commercially, little evidence informs

Externí odkaz: https://doaj.org/article/659b8bf41b784c46845ad91f1a2e3ebb

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Akademický článek

An Initial Evaluation of Human Plasma cMLC-1: A Potential Protein Biomarker for Trastuzumab-Induced Cardiotoxicity, Breast Cancer Screening and Progression

Autor: Ling Yu, Read Allen, Lin Jia, Ting Sun, Steven J. Isakoff, Marielle Scherrer-Crosbie, Allison M. Kehlmann, Hui Zheng, Amy Ly, Charlotte S. Walmsley, Katherine Hesler, Ava N. Varasteh, Christopher J. Pinto, Daniel E. McLoughlin, Wenjin Wu, Xinhui Wang

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

BackgroundTrastuzumab is a targeted therapy for human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, trastuzumab-induced cardiotoxicity (TIC) has been reported when trastuzumab is administered to patients as a single agent

Externí odkaz: https://doaj.org/article/3d195d2bb1e644cabb2a0e090b1d001e

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Akademický článek

RNA-Seq Transcriptome Analysis of Peripheral Blood From Cattle Infected With Mycobacterium bovis Across an Experimental Time Course

Autor: Kirsten E. McLoughlin, Carolina N. Correia, John A. Browne, David A. Magee, Nicolas C. Nalpas, Kevin Rue-Albrecht, Adam O. Whelan, Bernardo Villarreal-Ramos, H. Martin Vordermeier, Eamonn Gormley, Stephen V. Gordon, David E. MacHugh

Publikováno v: Frontiers in Veterinary Science, Vol 8 (2021)

Bovine tuberculosis, caused by infection with members of the Mycobacterium tuberculosis complex, particularly Mycobacterium bovis, is a major endemic disease affecting cattle populations worldwide, despite the implementation of stringent surveillance

Externí odkaz: https://doaj.org/article/0a59da780d9844058e5ac7e541456e2c

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Akademický článek

Photosensing and Thermosensing by Phytochrome B Require Both Proximal and Distal Allosteric Features within the Dimeric Photoreceptor

Autor: E. Sethe Burgie, Adam N. Bussell, Shu-Hui Lye, Tong Wang, Weiming Hu, Katrice E. McLoughlin, Erin L. Weber, Huilin Li, Richard D. Vierstra

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)

Abstract Phytochromes (Phys) encompass a diverse collection of bilin-containing photoreceptors that help plants and microorganisms perceive light through photointerconversion between red light (Pr) and far-red light (Pfr)-absorbing states. In additio

Externí odkaz: https://doaj.org/article/ff2574b5051f4fb99b8012360d76b029

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Supplementary Table from EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion–Positive Cholangiocarcinoma

Supplementary Table from EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion–Positive Cholangiocarcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931e04b614aba9b77872a721a0f534da
https://doi.org/10.1158/2159-8290.22540895

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Supplementary Figure from EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion–Positive Cholangiocarcinoma

Supplementary Figure from EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion–Positive Cholangiocarcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422abc098d7c3a0f2950cc928525d9be
https://doi.org/10.1158/2159-8290.22540901

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Data from EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion–Positive Cholangiocarcinoma

FGFR inhibitors are approved for the treatment of advanced cholangiocarcinoma harboring FGFR2 fusions. However, the response rate is moderate, and resistance emerges rapidly due to acquired secondary FGFR2 mutations or due to other less-defined mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd84f4a0eca53b00c987cfcb283dbf4
https://doi.org/10.1158/2159-8290.c.6549500.v1

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Akademický článek

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EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion–Positive Cholangiocarcinoma

Publikováno v: Cancer discovery, vol 12, iss 5
Cancer Discov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f839e8ad2f585085ef654d94967f6a41
https://doi.org/10.1158/2159-8290.cd-21-1168

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Akademický článek

RNA Sequencing (RNA-Seq) Reveals Extremely Low Levels of Reticulocyte-Derived Globin Gene Transcripts in Peripheral Blood From Horses (Equus caballus) and Cattle (Bos taurus)

Autor: Carolina N. Correia, Kirsten E. McLoughlin, Nicolas C. Nalpas, David A. Magee, John A. Browne, Kevin Rue-Albrecht, Stephen V. Gordon, David E. MacHugh

Publikováno v: Frontiers in Genetics, Vol 9 (2018)

RNA-seq has emerged as an important technology for measuring gene expression in peripheral blood samples collected from humans and other vertebrate species. In particular, transcriptomics analyses of whole blood can be used to study immunobiology and

Externí odkaz: https://doaj.org/article/8c813cd258e24dab9280462d492b8c32

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