Zobrazeno 1 - 10
of 594
pro vyhledávání: '"E, McLaren"'
Autor:
P. Benalcazar, R. Kolka, A. C. Diochon, R. R. Schindelbeck, T. Sahota, B. E. McLaren, John Stanovick
Publikováno v:
Agricultural & Environmental Letters, Vol 9, Iss 1, Pp n/a-n/a (2024)
Abstract A changing climate offers new opportunities to expand agriculture in northern latitudes, and understanding forest‐to‐agriculture land conversion impacts is critical to ensure soil sustainability. Using the Comprehensive Assessment of Soi
Externí odkaz:
https://doaj.org/article/40131aa199a1477ba8ce7684a8073891
Publikováno v:
JMIR Formative Research, Vol 8, p e54168 (2024)
BackgroundAbout 11 million Americans are caregivers for the 6.7 million Americans currently living with dementia. They provide over 18 billion hours of unpaid care per year, yet most have no formal dementia education or support. It is extremely diffi
Externí odkaz:
https://doaj.org/article/1c89c94479c74a329f2f1491a983742c
Autor:
Michael B. Lilly, Chunli Wu, Yu Ke, Wen‐Pin Chen, Adam C. Soloff, Kent Armeson, Noriko N. Yokoyama, Xiaotian Li, Liankun Song, Ying Yuan, Christine E. McLaren, Xiaolin Zi
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Purpose Our preclinical studies showed that lycopene enhanced the anti‐prostate cancer efficacy of docetaxel in animal models. A phase I trial (NCT0149519) was conducted to identify an optimum dose of synthetic lycopene in combination with
Externí odkaz:
https://doaj.org/article/5c65eef1c6c54d5eaf06f95c1a59df0d
Autor:
Freya R. Shepherd, Kate Davies, Kelly L. Miners, Sian Llewellyn-Lacey, Simon Kollnberger, James E. Redman, Melissa M. Grant, Kristin Ladell, David A. Price, James E. McLaren
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
In peripheral blood mononuclear cells from healthy human donors, the superantigens SpeC and TSST-1 are shown to specifically activate TRBV12-3/12-4+ memory T cells.
Externí odkaz:
https://doaj.org/article/2db234c82e7d48d5a9eec72de7ff370e
Autor:
Mariya Misheva, Konstantinos Kotzamanis, Luke C. Davies, Victoria J. Tyrrell, Patricia R. S. Rodrigues, Gloria A. Benavides, Christine Hinz, Robert C. Murphy, Paul Kennedy, Philip R. Taylor, Marcela Rosas, Simon A. Jones, James E. McLaren, Sumukh Deshpande, Robert Andrews, Nils Helge Schebb, Magdalena A. Czubala, Mark Gurney, Maceler Aldrovandi, Sven W. Meckelmann, Peter Ghazal, Victor Darley-Usmar, Daniel A. White, Valerie B. O’Donnell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Oxylipins are lipid mediators generated during infection for regulating inflammatory responses, but how they are removed is not completely clear. Here the authors show that cellular oxylipin removal is linked to mitochondria β-oxidation by CPT1, a m
Externí odkaz:
https://doaj.org/article/a3d11671abcf4409a6bdffc0da87c0f3
Autor:
Richard Skone, Daniel White, Bethan Phillips, Jennifer Evans, Robert Andrews, Benjamin Saunders, Kerry Hood, Mallinath Chakraborty, Sarah Edkins, Barbara Paquete, Sian Foulkes, Anna Barrow, Siske Struik, Valerie O'Donnell, Sara Ali, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Gareth L Watson, Peter Ghazal, Edward Parkinson, Sivakumar Oruganti, William John Watkins, Selyf Shapey, Rim al Samsam, Malcolm Gajraj, Michelle Jardine, Jong Eun Song, Lloyd Abood, Sarah Joanne Kotecha, Awen Evans, Iona Buchanan, Susan Bowes, Begum Ali, Maya Gore, Rhian Thomas-Turner, Federico Liberatore, Thomas Woolley
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction Early recognition and appropriate management of paediatric sepsis are known to improve outcomes. A previous system’s biology investigation of the systemic immune response in neonates to sepsis identified immune and metabolic markers th
Externí odkaz:
https://doaj.org/article/2d1c8f29b48f4539bf38b44ed3678f38
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionCognitive psychology posits that thinking about the future relies on memory such that those with memory impairment may have trouble imaging their future technology and other needs.MethodsWe conducted a content analysis of qualitative data
Externí odkaz:
https://doaj.org/article/f8baa937c9e04cea9f1224007f279a29
In the twenty-first century the Chinese economy has seen rapid development and massive social transformation. A central dilemma of the Chinese state is to ensure economic growth together with sustainable development, preservation of the environment,
Autor:
Daniel White, Sarah Bell, Shaun Oram, Robert Andrews, Mallinath Chakraborty, Sarah Edkins, W John Watkins, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Valerie B O’Donnell, Peter Ghazal, Edward Parkinson, Nicos Angelopoulos, Freya Shepherd, Kate Megan Megan Davies, Kate Siddall, Vikki Keeping, Kathryn Simpson, Federica Faggian, Maryanne Bray, Claire Bertorelli, Rachel E Collis, Mario Labeta
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment. Identifying biomarkers that can reliably diagnose
Externí odkaz:
https://doaj.org/article/372307b61d504c2f82b75430deb7c6d3
Publikováno v:
Aging and Health Research, Vol 2, Iss 1, Pp 100061- (2022)
Background: Persons with dementia are generally older and often have multiple other chronic conditions, necessitating several healthcare visits each year. Most live in the community supported by unpaid family caregivers who often assist with healthca
Externí odkaz:
https://doaj.org/article/28d46cec8e7f488bafb88723d143df61