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Inhibitor development and mortality in non-severe hemophilia A

Autor: C.L. Eckhardt, J.I. Loomans, A.S. van Velzen, M. Peters, E.P. Mauser‐Bunschoten, R. Schwaab, M.G. Mazzucconi, A. Tagliaferri, B. Siegmund, S.E. Reitter‐Pfoertner, J.G. van der Bom, K. Fijnvandraat, P.W. Kamphuisen, K. Peerlinck, J. Oldenburg, E. Santagostino, J. Astermark, C.L Eckhardt, A.S van Velzen, N. Streefkerk, J.L. Loomans, A. van Eijkelenburg, A.J. Jansen, C.C. Kruijt, B. van Tienoven, A.C.G. van Baar, I.W. Corten, K. Meijer, M.R. Nijziel, N. Dors, K. Hamulyak, E. Beckers, P.P. Brons, B.A.P. Laros‐van Gorkom, W.L. van Heerde, F. Leebeek, M. Kruip, M.H. Cnossen, E. Mauser‐Bunschoten, K. Fischer, F.J. Smiers, C. Hermans, R. Klamroth, C. Escuriola‐Ettingshausen, C. Königs, P. Petrini, M. Holmström, A. Mäkipernaa, C. Male, I. Pabinger, R.D. Keenan, R. Liesner, K. Khair, T.T. Yee, D.P. Hart, S. Rangarajan, M. Mitchell, G. Thompson, S. Haya, A. Moret, A.R. Cid, V. Jimenez‐Yuste, M.E. Mancuso, M.G. Mazzuconni, C. Santoro, M. Morfini, G. Castaman, P. Schinco, G.F. Rivolta, H. Platokouki, S. McRae

Publikováno v: Journal of Thrombosis and Haemostasis, 13(7), 1217-1225. Wiley
Journal of Thrombosis and Haemostasis, 13(7), 1217-1225
Journal of thrombosis and haemostasis, 13(7), 1217-1225. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 13, 1217-25
Journal of Thrombosis and Haemostasis, 13, 7, pp. 1217-25
Journal of Thrombosis and Haemostasis, 13(7), 1217. Wiley-Blackwell

BACKGROUND: The life expectancy of non-severe hemophilia A (HA) patients equals the life expectancy of the non-hemophilic population. However, data on the effect of inhibitor development on mortality and on hemophilia-related causes of death are scar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5b169bde53c72df8027f9087821d9f
https://research.rug.nl/en/publications/1e934363-fdf0-4dda-a41c-959edc3a8469

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Women with moderate and severe Von Willebrand disease have a high morbidity of gynecological and obstetric bleeding

Autor: E., De Wee, M., Knol, E., Mauser-Bunschoten, A., Van Der Bom, M., Degenaar-Dujardin, J.C.J., Eikenboom, K., Fijnvandraat, A., De Goede-Bolder, B., Laros-Van Gorkom, P., Ypma, S., Zweegman, K., Meijer

Publikováno v: Blood, 116(21). American Society of Hematology
E., D W, M., K, E., M-B, A., V D B, M., D-D, J.C.J., E, K., F, A., D G-B, B., L-V G, P., Y, S., Z & K., M 2010, ' Women with moderate and severe Von Willebrand disease have a high morbidity of gynecological and obstetric bleeding ', Blood, vol. 116, no. 21 . < http://abstracts.hematologylibrary.org/cgi/content/abstract/116/21/542?maxtoshow=&hits=60&RESULTFORMAT=&searchid=1&FIRSTINDEX=780&displaysectionid=Oral+Session&fdate=1/1/2010&tdate=12/31/2010&resourcetype=HWCIT http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE >

Introduction: Von Willebrand Disease (VWD) is the most common inherited bleeding disorder worldwide. Men and women are equally likely to be affected, but in women VWD is more often clinically manifest because of bleeding associated with menstruation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aaa311b6c8ac5a0bb7e8a58e8c91445b
https://research.vumc.nl/en/publications/d55f1e98-2904-4248-9a6c-5b675d1635d4

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Progression to AIDS in relation to clinical factors and clotting product consumption. A 14-year follow-up of a cohort of 52 Dutch HIV-1-infected haemophilic patients

Autor: G, Roosendaal, Y, van der Schouw, E, Mauser-Bunschoten, J, Borleffs, H, van den Berg

Publikováno v: Vox sanguinis. 75(4)

In order to describe the progression of HIV disease in a cohort of Dutch HIV-1-infected patients with haemophilia and to study the influence of clinical and clotting factors, we performed a 15-year longitudinal clinical and laboratory study.The progr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7293d4e200feb69b2667487815645954
https://pubmed.ncbi.nlm.nih.gov/9873260

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Dominant C2 domain epitope specificity of inhibitor antibodies elicited by a heat pasteurized product, factor VIII CPS-P, in previously treated hemophilia A patients without inhibitors

Autor: Y, Sawamoto, R, Prescott, D, Zhong, E L, Saenko, E, Mauser-Bunschoten, K, Peerlinck, M, van den Berg, D, Scandella

Publikováno v: Thrombosis and haemostasis. 79(1)

From June, 1990, to November, 1991, in The Netherlands and Belgium, 16 previously treated severe hemophilia A patients (PTP) developed inhibitors after exposure to factor VIII CPS-P, a new heat pasteurized product. A previously untreated patient (PUP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6700ccdeb5fb6df64068abb8ac7dd714
https://pubmed.ncbi.nlm.nih.gov/9459325

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Akademický článek

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A deletion mutation causes hemophilia B in Lhasa Apso dogs

Autor: A E, Mauser, J, Whitlark, K M, Whitney, C D, Lothrop

Publikováno v: Blood. 88(9)

Hemophilia B is a bleeding disorder caused by a deficiency of clotting factor IX (FIX). A colony of FIX deficient Lhasa Apso dogs has been established and the molecular basis of hemophilia B has been determined. The plasma factor IX levels were1% of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d733bc2802513f4d17ac6ed62bca684a
https://pubmed.ncbi.nlm.nih.gov/8896410

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A profile of home health users in 1992

Autor: E, Mauser, N A, Miller

Publikováno v: Health Care Financing Review

Recently, the use of home health services by Medicare beneficiaries has been growing. From 1987 to 1992, the percentage of all enrollees receiving home health rose from 4.8 to 7.2 percent, while the average number of visits among users increased from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9d714bcb75fa09ce82e38a93377d11e
https://pubmed.ncbi.nlm.nih.gov/10140153

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The Nijmegen modification of the Bethesda assay for factor VIII:C inhibitors: improved specificity and reliability

Autor: B, Verbruggen, I, Novakova, H, Wessels, J, Boezeman, M, van den Berg, E, Mauser-Bunschoten

Publikováno v: Thrombosis and haemostasis. 73(2)

Antibodies against factor VIII coagulant activity can appear in haemophiliacs who are treated with factor VIII preparations but also spontaneously in non-haemophiliacs. The Bethesda assay is the most commonly used method to detect these antibodies, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::389b5c81368a140a593e6d9658cbf875
https://pubmed.ncbi.nlm.nih.gov/7792738

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