Výsledky vyhledávání

Characterization of Therapeutic Proteins

Autor: M. Shapiro, N. Kirschbaum, J. Liu, E. B. Struble, E. Marszal

Publikováno v: Topics in Medicinal Chemistry ISBN: 9783319418162

Therapeutic proteins are large biological molecules with complex structures and functions produced through complex manufacturing processes, which include multiple unit operations with finely tuned control parameters. The characterization of therapeut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c01778c19fd6099f596ae231cf06f12a
https://doi.org/10.1007/7355_2015_5005

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An international collaborative study to establish the WHO 1st international standard for alpha-1-antitrypsin

Autor: Peter Rigsby, E Marszal, Colin Longstaff, Craig Thelwell

Publikováno v: Vox Sanguinis. 101:83-89

Background and Objectives The aim was to establish the 1st International Standard (IS) for alpha-1-antitrypsin (AAT) to standardise potency assignment of therapeutic products, calibrated in moles and mg active AAT in line with product labelling pract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6701e00e56892b9f62d092801b277fc
https://doi.org/10.1111/j.1423-0410.2010.01459.x

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Akademický článek

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Deletion screening and carrier detection in Duchenne muscular dystrophy in Polish population via direct analysis of DNA and RNA transcripts

Autor: J. Zimowski, B. Galas-Zgorzalewicz, A. Szczególa-Przymusiak, P. Nuc, Tomasz Ciesielski, E. Marszal, D. Lisiecka, J. Kwiatkowska, J. Sowinska, E. Emich-Widera, H. Chlebowska, R. Slonski

Publikováno v: Biochimie. 79:439-448

Analysis of 102 Polish Duchenne/Becker muscular dystrophy (D/BMD) patients was performed by 'multiplex' amplification of 22 fragments of the DMD/BMD gene and deletions were found in 55% of the patients. The data obtained using PCR were compared with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64078fec4d1408756ca02d4e664947e
https://doi.org/10.1016/s0300-9084(97)86154-8

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An international collaborative study to establish the WHO 1st international standard for alpha-1-antitrypsin

Autor: C, Thelwell, E, Marszal, P, Rigsby, C, Longstaff

Publikováno v: Vox sanguinis. 101(1)

The aim was to establish the 1st International Standard (IS) for alpha-1-antitrypsin (AAT) to standardise potency assignment of therapeutic products, calibrated in moles and mg active AAT in line with product labelling practice. Assigning total prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8227ea10937e9f78bfcfaacecc25960a
https://pubmed.ncbi.nlm.nih.gov/21668863

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High reliability computing for control and safety

Autor: W. Goble, E. Marszal

Publikováno v: PACS2001. Proceedings of the 2001 Particle Accelerator Conference (Cat. No.01CH37268).

Safety Programmable Logic Controllers (PLCs) are special purpose computers that are used to provide critical control and safety applications for automation users. There are serious questions though about the use of programmable systems for critical c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de3328036c33ca79fc2d8d23ed91ece
https://doi.org/10.1109/pac.2001.987493

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Dihydrofolate reductase synthesis in the presence of immobilized methotrexate. An approach to a continuous cell-free protein synthesis system

Autor: E, Marszal, W H, Scouten

Publikováno v: Journal of molecular recognition : JMR. 9(5-6)

Dihydrofolate reductase was synthesized in a batch system in the presence of the affinity ligand methotrexate, bound to various matrices. Two types of gel were used: commercial methotrexate-agarose with pores inaccessible for translation machinery an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c380823b8e241ab863a3bea15ca1898a
https://pubmed.ncbi.nlm.nih.gov/9174938

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Akademický článek

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