Zobrazeno 1 - 10
of 3 357
pro vyhledávání: '"E, Lloyd"'
Autor:
Haokun Yuan, Rebecca D. Kehm, Josephine M. Daaboul, Susan E. Lloyd, Jasmine A. McDonald, Lina Mu, Parisa Tehranifar, Kai Zhang, Mary Beth Terry, Wan Yang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The impact of common environmental exposures in combinations with socioeconomic and lifestyle factors on cancer development, particularly for young adults, remains understudied. Here, we leveraged environmental and cancer incidence data coll
Externí odkaz:
https://doaj.org/article/979f2b92fc6944bdbbd7607ca04ed66e
Autor:
Simon A. Hunt, Andrew M. Walker, Oliver T. Lord, Stephen Stackhouse, Lewis Schardong, Lora S. Armstrong, Andrew J. Parsons, Geoffrey E. Lloyd, John Wheeler, Danielle M. Fenech, Stefan Michalik, Matthew L. Whitaker
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 25, Iss 6, Pp n/a-n/a (2024)
Abstract Seismic observations show the Earth's inner core has significant and unexplained variation in seismic attenuation with position, depth and direction. Interpreting these observations is difficult without knowledge of the visco‐ or anelastic
Externí odkaz:
https://doaj.org/article/cf8da1335e164f1883b7849db2737d72
Autor:
Jake Lin, Elaheh Moradi, Karoliina Salenius, Suvi Lehtipuro, Tomi Häkkinen, Jutta E. Laiho, Sami Oikarinen, Sofia Randelin, Hemang M. Parikh, Jeffrey P. Krischer, Jorma Toppari, Åke Lernmark, Joseph F. Petrosino, Nadim J. Ajami, Jin-Xiong She, William A. Hagopian, Marian J. Rewers, Richard E. Lloyd, Kirsi J. Rautajoki, Heikki Hyöty, Matti Nykter, the TEDDY Study Group
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Although the genetic basis and pathogenesis of type 1 diabetes have been studied extensively, how host responses to environmental factors might contribute to autoantibody development remains largely unknown. Here, we use longitudinal blood t
Externí odkaz:
https://doaj.org/article/80ebd0159183481dafbd9063fd5905f9
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26393- (2024)
Huntington's disease is caused by an expansion of CAG repeats in exon 1 of the huntingtin gene encoding an extended PolyQ tract within the Huntingtin protein (mHtt). This expansion results in selective degeneration of striatal medium spiny projection
Externí odkaz:
https://doaj.org/article/f197343a68a34d23a5fab097d89180ab
Autor:
Bhaskar Roy, Allison Peck, Teresinha Evangelista, Gerald Pfeffer, Leo Wang, Jordi Diaz‐Manera, Manisha Korb, Matthew P. Wicklund, Margherita Milone, Miriam Freimer, Hani Kushlaf, Rocio‐Nur Villar‐Quiles, Tanya Stojkovic, Merrilee Needham, Johanna Palmio, Thomas E. Lloyd, Benison Keung, Tahseen Mozaffar, Conrad Chris Weihl, Virginia Kimonis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 686-695 (2023)
Abstract Valosin‐containing protein (VCP)‐associated multisystem proteinopathy (MSP) is a rare genetic disorder with abnormalities in the autophagy pathway leading to various combinations of myopathy, bone diseases, and neurodegeneration. Ninety
Externí odkaz:
https://doaj.org/article/a319ff4d3dcf4e0d84c1086d8301b2c9
Autor:
Samuel G Smith, Samuel Smith, Robbie Foy, Andrew T Chan, Ruth Langley, Jack Cuzick, Mairead McKenzie, John Burn, Lucy Ziegler, Chris Hawkey, Colin Crooks, Paola Patrignani, Belinda Nedjai, Carlo Patrono, Mairead MacKenzie, Kelly E Lloyd, Sophie M C Green, Louise H Hall, David G Taylor, Frances Balkwill, Tim Bishop, Bianca Rocca, Laura Greaves
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Objectives Aspirin could be offered for colorectal cancer prevention for the UK general population. To ensure the views of the general population are considered in future guidance, we explored public perceptions of aspirin for preventive therapy.Desi
Externí odkaz:
https://doaj.org/article/20980d0cfa3d424d80c0ede8bfc55f25
Autor:
Maria Casal-Dominguez, Iago Pinal-Fernandez, Katherine Pak, Sandra Muñoz-Braceras, Jose C. Milisenda, Jiram Torres-Ruiz, Stefania Dell′Orso, Faiza Naz, Gustavo Gutierrez-Cruz, Yaiza Duque-Jaimez, Ana Matas-Garcia, Laura Valls-Roca, Gloria Garrabou, Ernesto Trallero-Araguas, Brian Walitt, Lisa Christopher-Stine, Thomas E. Lloyd, Julie J. Paik, Jemima Albayda, Andrea Corse, Josep Maria Grau, Albert Selva-O’Callaghan, Andrew L. Mammen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Complement proteins are deposited in the muscles of patients with myositis. However, the local expression and regulation of complement genes within myositis muscle have not been well characterized. In this study, bulk RNA sequencing (RNAseq)
Externí odkaz:
https://doaj.org/article/432560f2a1924ebb82edb93b6abbedca
Autor:
Eva B. Warreman, Susan E. Lloyd, Laura A. Nooteboom, Pieter J.M. Leenen, Mary Beth Terry, Hans W. Hoek, Elisabeth F.C. van Rossum, Robert R.J.M. Vermeiren, Wietske A. Ester
Publikováno v:
EClinicalMedicine, Vol 64, Iss , Pp 102211- (2023)
Summary: Background: People who give care to autistic individuals (autism-caregivers) experience higher levels of caregiver strain than people who provide care for individuals with other chronic conditions (non-autism-caregivers). This places them at
Externí odkaz:
https://doaj.org/article/91af542f3ca4450ba147f554db79e388
Publikováno v:
Preventive Medicine Reports, Vol 34, Iss , Pp 102220- (2023)
Women with a family history of breast cancer have an increased lifetime risk of the disease. Delay in symptom presentation can lead to poorer outcomes. Low awareness of breast cancer symptoms and help-seeking barriers have been associated with delay
Externí odkaz:
https://doaj.org/article/ab4514def8a745bbbf86c2094640de0f
Autor:
Kelly E. Lloyd, Robbie Foy, Louise H. Hall, Lucy Ziegler, Sophie M. C. Green, Zainab F. Haider, David G. Taylor, Mairead MacKenzie, Samuel G. Smith
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background The National Institute for Health and Care Excellence (NG151) recommends considering daily aspirin for people with Lynch syndrome to reduce colorectal cancer risk. However, deciding whether to initiate aspirin could be a complex d
Externí odkaz:
https://doaj.org/article/15155f6d11dc4aa88def9fab5486c5d4