Zobrazeno 1 - 10
of 3 044
pro vyhledávání: '"E, Hennessy"'
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Posttraumatic stress disorder (PTSD) is characterised by dysregulated hypothalamic-pituitary-adrenal axis activity and altered glucocorticoid receptor sensitivity. Early treatment with glucocorticoids may reduce PTSD risk, although the effec
Externí odkaz:
https://doaj.org/article/7cb3d0e17947423f8235111b51ccaedd
Autor:
Leslie E. Morgan, Ana M. Jaramillo, Siddharth K. Shenoy, Dorota Raclawska, Nkechinyere A. Emezienna, Vanessa L. Richardson, Naoko Hara, Anna Q. Harder, James C. NeeDell, Corinne E. Hennessy, Hassan M. El-Batal, Chelsea M. Magin, Diane E. Grove Villalon, Gregg Duncan, Justin S. Hanes, Jung Soo Suk, David J. Thornton, Fernando Holguin, William J. Janssen, William R. Thelin, Christopher M. Evans
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
In asthma, mucus plugging is an important cause of airflow obstruction, but it is not targeted by widely used bronchodilator and anti-inflammatory drugs. Here the authors show that reduction of disulfide bonds that hold mucin polymers together revers
Externí odkaz:
https://doaj.org/article/2fb68d67a4a24797aac17403bb6726b1
Autor:
Ravi K. Das, Grace Gale, Katie Walsh, Vanessa E. Hennessy, Georges Iskandar, Luke A. Mordecai, Brigitta Brandner, Merel Kindt, H. Valerie Curran, Sunjeev K. Kamboj
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Memories linking environmental cues to alcohol reward are involved in the development and maintenance of heavy drinking. Here, the authors show that a single dose of ketamine, given after retrieval of alcohol-reward memories, disrupts the reconsolida
Externí odkaz:
https://doaj.org/article/606a0f7b9edd4aabbf1cf2a46ff7ac24
Publikováno v:
The American Biology Teacher, 1968 May 01. 30(5), 434-435.
Externí odkaz:
https://www.jstor.org/stable/4442123
Autor:
Evgenia Dobrinskikh, Corinne E. Hennessy, Jonathan S. Kurche, Eunjoo Kim, Alani M. Estrella, Jonathan Cardwell, Ivana V. Yang, David A. Schwartz
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:62-74
Autor:
Laura A. Hancock, Corinne E. Hennessy, George M. Solomon, Evgenia Dobrinskikh, Alani Estrella, Naoko Hara, David B. Hill, William J. Kissner, Matthew R. Markovetz, Diane E. Grove Villalon, Matthew E. Voss, Guillermo J. Tearney, Kate S. Carroll, Yunlong Shi, Marvin I. Schwarz, William R. Thelin, Steven M. Rowe, Ivana V. Yang, Christopher M. Evans, David A. Schwartz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The promoter variant rs35705950 confers a gain of function to the MUC5B gene and is the dominant risk factor for idiopathic pulmonary fibrosis. Here the authors show that mice overexpressing Muc5b in distal airspaces show impaired mucociliary clearan
Externí odkaz:
https://doaj.org/article/179e7c61d4b74fa68c0ec80470732ff6
Autor:
Tsukasa, Okamoto, Evgenia, Dobrinskikh, Corinne E, Hennessy, Naoko, Liu, Marvin I, Schwarz, Christopher M, Evans, Andrew P, Fontenot, Ivana V, Yang, David A, Schwartz
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 323(3)
Previously we have shown that a gain-of-function
Autor:
Tsukasa Okamoto, Evgenia Dobrinskikh, Corinne E. Hennessy, Naoko Liu, Marvin I. Schwarz, Christopher M. Evans, Andrew P. Fontenot, Ivana V. Yang, David A. Schwartz
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 323:L329-L337
Previously we have shown that a gain-of-function MUC5B promoter variant (rs35705950) is the strongest risk factor for the development of idiopathic pulmonary fibrosis. We have also found that Muc5b overexpression reduces mucociliary clearance in mice
Autor:
Eunjoo Kim, Susan K. Mathai, Ian T. Stancil, Xiaoqian Ma, Ashley Hernandez-Gutierrez, Jessica N. Becerra, Emilette Marrero-Torres, Corinne E. Hennessy, Kristina Hatakka, Eric P. Wartchow, Alani Estrella, Jonathan P. Huber, Jonathan H. Cardwell, Ellen L. Burnham, Yingze Zhang, Christopher M. Evans, Eszter K. Vladar, David A. Schwartz, Evgenia Dobrinskikh, Ivana V. Yang
Publikováno v:
American journal of respiratory cell and molecular biology. 67(2)
We previously identified a novel molecular subtype of idiopathic pulmonary fibrosis (IPF) defined by increased expression of cilium-associated genes, airway mucin gene
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