Zobrazeno 1 - 10
of 1 113
pro vyhledávání: '"E, Healy"'
Autor:
Anne-Laure Leblond, Birgit Helmchen, Maliki Ankavay, Daniela Lenggenhager, Jasna Jetzer, Fritjof Helmchen, Hueseyin Yurtsever, Rossella Parrotta, Marc E. Healy, Amiskwia Pöschel, Enni Markkanen, Nasser Semmo, Martin Ferrié, Laurence Cocquerel, Harald Seeger, Helmut Hopfer, Beat Müllhaupt, Jérôme Gouttenoire, Darius Moradpour, Ariana Gaspert, Achim Weber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Hepatitis E virus (HEV) infection, one of the most common forms of hepatitis worldwide, is often associated with extrahepatic, particularly renal, manifestations. However, the underlying mechanisms are incompletely understood. Here, we repor
Externí odkaz:
https://doaj.org/article/2e0acd6efb7748d6ab4fa79b0d50a92c
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract In the initial hours following the application of the calcium channel blocker (CCB) nifedipine to microtissues consisting of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), we observe notable variations in the drug’
Externí odkaz:
https://doaj.org/article/0258195002c146189b9d09b1cfacb426
Autor:
Laura E Healy, Xianglu Zhu, Milica Pojic, Mahesha M Poojary, James Curtin, Uma Tiwari, Carl Sullivan, Brijesh K Tiwari
Publikováno v:
International Journal of Food Properties, Vol 25, Iss 1, Pp 2073-2088 (2022)
Market demand for “clean and green” food products is increasing, and so there is growing opportunity for the seaweed aquaculture industry to take a position as a key food producer in this area. In this study, in order to investigate the impact of
Externí odkaz:
https://doaj.org/article/22812d4c61bd4aaf9f4d24cce296e931
Autor:
Matthew J. Powell-Palm, Verena Charwat, Berenice Charrez, Brian Siemons, Kevin E. Healy, Boris Rubinsky
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-7 (2021)
Powell-Palm et al. demonstrate sub-zero centigrade preservation and revival of autonomously beating, 3D human induced pluripotent stem cell (hiPSC)-derived cardiac microtissues via isochoric supercooling, without the use of chemical cryoprotectants.
Externí odkaz:
https://doaj.org/article/e91e22959744442889b1812d5fc408b0
Autor:
Bérénice Charrez, Verena Charwat, Brian Siemons, Henrik Finsberg, Evan W. Miller, Andrew G. Edwards, Kevin E. Healy
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 1155-1165 (2021)
Abstract Only a handful of US Food and Drug Administration (FDA) Emergency Use Authorizations exist for drug and biologic therapeutics that treat severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) infection. Potential therapeutics inc
Externí odkaz:
https://doaj.org/article/909a322bfea042109b6b1af1e914fe94
Autor:
Laura E. Healy, Xianglu Zhu, Milica Pojić, Carl Sullivan, Uma Tiwari, James Curtin, Brijesh K. Tiwari
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 386 (2023)
Seaweed is in the spotlight as a promising source of nutrition for humans as the search for sustainable food production systems continues. Seaweed has a well-documented rich nutritional profile containing compounds such as polyphenols, carotenoids an
Externí odkaz:
https://doaj.org/article/b71c150f088d4eb48fde48d586a45313
Autor:
Bérénice Charrez, Verena Charwat, Brian A. Siemons, Ishan Goswami, Courtney Sakolish, Yu-Syuan Luo, Henrik Finsberg, Andrew G. Edwards, Evan W. Miller, Ivan Rusyn, Kevin E. Healy
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Despite global efforts, it took 7 months between the proclamation of global SARS-CoV-2 pandemic and the first FDA-approved treatment for COVID-19. During this timeframe, clinicians focused their efforts on repurposing drugs, such as hydroxychloroquin
Externí odkaz:
https://doaj.org/article/24b7f9e303f54de4a211eb7cf95a932a
Autor:
M. Ahmad, MB Bch BaO, MRCSEd, V. Sekar, MRCSEd, PhD, E. Healy, FRCSPath, I. Rennie, FRCR, S. Cooke, FRCS (SN)
Publikováno v:
Interdisciplinary Neurosurgery, Vol 17, Iss , Pp 36-39 (2019)
We present the case of a 33 year old lady presenting with progressive cranial nerve palsies caused by an Extrarenal Rhabdoid tumour manifesting as a sellar/suprasellar mass. We share our experience of managing the tumour and review the existing liter
Externí odkaz:
https://doaj.org/article/8a5b8c4c23c64d47ad4f9f98d93f179d
Autor:
Felipe T. Lee-Montiel, Alexander Laemmle, Verena Charwat, Laure Dumont, Caleb S. Lee, Nathaniel Huebsch, Hideaki Okochi, Matthew J. Hancock, Brian Siemons, Steven C. Boggess, Ishan Goswami, Evan W. Miller, Holger Willenbring, Kevin E. Healy
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Three-dimensional (3D) microphysiological systems (MPSs) mimicking human organ function in vitro are an emerging alternative to conventional monolayer cell culture and animal models for drug development. Human induced pluripotent stem cells (hiPSCs)
Externí odkaz:
https://doaj.org/article/027539b15d064925b90ab47e1ab3702a
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) offer a new means to study and understand the human cardiac action potential, and can give key insight into how compounds may interact with important molecular pathways to d
Externí odkaz:
https://doaj.org/article/9a6ac2446c80499083a66e7eb999985e