Zobrazeno 1 - 10
of 119
pro vyhledávání: '"E, Harfst"'
Autor:
Keith N. Leppard, E. Harfst
Publikováno v:
Virus Genes. 18:97-106
Specific mutation of the DNA binding protein (DBP) of human adenovirus types 2 and 5 can extend the host range of these viruses to simian cells. These mutations replace histidine at position 130 in the highly phosphorylated N-terminal domain of DBP w
Autor:
P, Rich, B, Sigurgeirsson, D, Thaci, J-P, Ortonne, C, Paul, R E, Schopf, A, Morita, K, Roseau, E, Harfst, A, Guettner, M, Machacek, C, Papavassilis
Publikováno v:
The British journal of dermatology. 168(2)
Interleukin (IL)-17A has major proinflammatory activity in psoriatic lesional skin.To assess the efficacy and safety of secukinumab, a fully human IgG1κ monoclonal anti-IL-17A antibody, in moderate-to-severe plaque psoriasis in a phase II regimen-fi
Autor:
P. Rich, B. Sigurgeirsson, D. P. Thaci, J.-P. Ortonne, C. Paul, R.E. Schopf, A. Morita, K. Roseau, E. Harfst, A. Guettner, M. Machacek, C. Papavassilis
Publikováno v:
British Journal of Dermatology.
Publikováno v:
Europe PubMed Central
Intercellular junctions are fundamental to the interactions between cells. By means of these junctions, the activities of the individual cells that make up tissues are co-ordinated, enabling each tissue system to function as an integrated whole. In t
Autor:
Stephen Nussey, Susan Povey, Nicholas D. Carter, Alan P. Johnstone, Yvonne J. K. Edwards, Antal Nógrádi, Christiane Kelly, E. Harfst
Publikováno v:
Annals of Human Genetics. 56:255-265
Summary Glutamic acid decarboxylase (GAD) catalyses the conversion of l-glutamic acid to the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Two forms of human GAD, GAD65 and GAD67, are encoded by two separate genes. A full length human GAD6
Publikováno v:
Molecular and Cellular Endocrinology. 83:117-123
In order to produce significant quantities of the human thyrotrophin (TSH) receptor we have investigated the use of two eukaryotic high expression systems. DNA encoding the receptor was obtained by the polymerase chain reaction (PCR) applied to thyro
Autor:
E, Harfst, K N, Leppard
Publikováno v:
Virus genes. 18(2)
Specific mutation of the DNA binding protein (DBP) of human adenovirus types 2 and 5 can extend the host range of these viruses to simian cells. These mutations replace histidine at position 130 in the highly phosphorylated N-terminal domain of DBP w
Publikováno v:
Molecular and cellular endocrinology. 105(2)
Monoclonal antibodies have been produced that recognize the native human thyrotropin receptor by using a sensitive screening protocol based on flow cytofluorimetry combined with recombinant eukaryotic cells expressing high levels of the full-length f
Publikováno v:
Molecular and cellular endocrinology. 102(1-2)
The structure of the human thyrotropin receptor expressed as a recombinant protein in eukaryotic cells was investigated by immunochemical and functional means using two types of polyclonal rabbit antisera: one raised against the large N-terminal extr
Publikováno v:
Journal of molecular endocrinology. 9(3)
DNA encoding the N-terminal 415 residues of the human thyrotrophin receptor (predicted to code for the large extracellular region) was introduced into Chinese hamster ovary (CHO) cells using the glutamine synthetase/cytomegalovirus amplifiable expres