Zobrazeno 1 - 10
of 557
pro vyhledávání: '"E, Handman"'
Publikováno v:
Immunology today. 8(6)
Vaccination is one of the most cost-effective means of controlling and eradicating infectious disease but at present there is no vaccine against any human parasitic disease. Developments in gene cloning have focused attention on protein antigen vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::221a5504048bd29d8fd3ca090ce6e536
https://pubmed.ncbi.nlm.nih.gov/25290218
https://pubmed.ncbi.nlm.nih.gov/25290218
Publikováno v:
The Journal of Immunology. 149:2715-2721
Limiting dilution analysis was used to estimate the frequency of clonogenic Ag-specific CD4+ T lymphocytes in draining lymph nodes of mice over the course of infection with Leishmania major, and to measure the production of IL-2, IL-3, IL-4, IFN-gamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7faa95b23c823fe83cd3f99287c229a2
https://doi.org/10.4049/jimmunol.149.8.2715
https://doi.org/10.4049/jimmunol.149.8.2715
Autor:
E, Handman
Publikováno v:
Advances in parasitology. 44
Leishmania are digenetic protozoa which inhabit two highly specific hosts, the sandfly, where they grow as motile flagellated promastigotes in the gut, and the mammalian macrophage, where they survive and grow intracellularly as non-flagellated amast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be2f1abcc33496188525402a7beb240f
https://pubmed.ncbi.nlm.nih.gov/10563394
https://pubmed.ncbi.nlm.nih.gov/10563394
Publikováno v:
European journal of immunology. 29(9)
As in other infectious diseases, the outcome of a Leishmania major infection is closely tied to the T helper cell response type; progressive disease is associated with a predominant Th2 lymphocyte response, healing with a Th1 response. In mice, susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::899567bd274f0cec0384ea1b1475fc60
https://pubmed.ncbi.nlm.nih.gov/10508279
https://pubmed.ncbi.nlm.nih.gov/10508279
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(8)
Experimental systems based on immunization with plasmid DNA or immune-stimulating complexes were used to delineate the requirements for generation of protective immunity against murine leishmaniasis. Vaccination with plasmid DNA encoding the host-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14dbaea577475f8e5b92fb81fd964dac
https://pubmed.ncbi.nlm.nih.gov/9558102
https://pubmed.ncbi.nlm.nih.gov/9558102
Autor:
E. Handman
Publikováno v:
Parasitology today (Personal ed.). 13(6)
The approach to the development of a Leishmania vaccine has undergone a revolution since its early beginnings with the ancient practice of leishmazation: the inoculation of infectious parasites from an active lesion in order to produce a self-healing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbafe65e3fa9594ab192b9d8ffcebfb4
https://pubmed.ncbi.nlm.nih.gov/15275077
https://pubmed.ncbi.nlm.nih.gov/15275077
Publikováno v:
The Journal of biological chemistry. 268(25)
Intracellular amastigotes of Leishmania major produce 6 x 10(4) copies/cell of a lipophosphoglycan (LPG) that is structurally distinct from the LPG produced by the extracellular promastigote form of L. major, Leishmania donovani, and Leishmania mexic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::daf3ff805348e0f5a4125bd5155950f5
https://pubmed.ncbi.nlm.nih.gov/8360147
https://pubmed.ncbi.nlm.nih.gov/8360147
Publikováno v:
Critical Care Medicine. 32:A134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48efe4a7ab39b5d5d447893087f3182d
https://doi.org/10.1097/00003246-200412001-00478
https://doi.org/10.1097/00003246-200412001-00478
Publikováno v:
Critical Care Medicine. 32:A30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4df04fc335303241e7285d6a950b1cb7
https://doi.org/10.1097/00003246-200412001-00118
https://doi.org/10.1097/00003246-200412001-00118