Zobrazeno 1 - 10
of 102
pro vyhledávání: '"E, HORMAECHE"'
Publikováno v:
Scopus-Elsevier
In the present study we evaluated the role of B cells in acquired immunity toSalmonellainfection by using gene-targeted B-cell-deficient innately susceptible mice on a C57BL/6 background (Igh-6−/−).Igh-6−/−mice immunized with a live, attenuat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d64a232e139bed96970a8c65ffc4e5
https://doi.org/10.1128/iai.68.1.46-53.2000
https://doi.org/10.1128/iai.68.1.46-53.2000
Autor:
Fidel Zavala, Michail H. Karavolos, C E Hormaeche, Jeong Jin Lee, Duncan J. Maskell, David M. Bulmer, C. M. Anjam Khan, Shahid Khan, Nicola D. McKelvie, Raquel DeMarco
Publikováno v:
FEMS Immunology & Medical Microbiology. 52:237-246
Live Salmonella vaccines are limited in use by the inherent toxicity of the lipopolysaccharide. The waaN gene encodes a myristyl transferase required for the secondary acylation of lipid A in lipopolysaccharide. A waaN mutant exhibits reduced inducti
Autor:
Raquel Demarco Carlos E. Hormaeche, C. M. Anjam Khan, Wen-Tssann Liu, Jeong Jin Lee, David M. Bulmer, Abdelmounaaim Allaoui, Michail H. Karavolos
Publikováno v:
Microbial Pathogenesis. 42:2-10
Pathogenic bacteria employ a variety of mechanisms to resist a barrage of stresses they encounter during active growth in or outside the host as well as during growth stasis. An in silico screen of the Salmonella genome sequence revealed that Salmone
Autor:
Richard D. Hayward, Vassilis Koronakis, Julie A. Musson, Carlos E. Hormaeche, Alexei A. Delvig, John H. Robinson
Publikováno v:
European Journal of Immunology. 32:2664-2671
We have identified Salmonella invasion protein C (SipC) as a target antigen for CD4 T cell recognition in mice infected with Salmonella typhimurium. SipC is a product of the type III secretion system encoded by S. typhimurium pathogenicity island 1.
Publikováno v:
Infection and Immunity. 69:4657-4660
The infectivities of 66 Listeria monocytogenes isolates were assessed by intragastric inoculation of mice. Eight were poorly infective. Serovars 4b and 1/2 were more infective than serovars 3 and 4nonb. A noninfective isolate was cleared more rapidly
Publikováno v:
Vaccine. 19:460-469
A live attenuated Salmonella typhimurium vaccine candidate, LVR01, was constructed by introducing a null deletion into the aroC gene of the parental canine S. typhimurium isolate, P228067. LVR01 was used to orally deliver to the canine immune system
Autor:
Elizabeth A. Somner, Anthony A. Holder, Solabomi A. Ogun, Lilian M. Spencer Valero, J. A. Harrison, C E Hormaeche, Anjam C. M. Khan, Jeong Jin Lee, Katharine A. Sinha
Publikováno v:
Microbiology. 145:221-229
The 19 kDa carboxy-terminal domain of Plasmodium yoelii merozoite surface protein-1 (MSP1(19)) was expressed in Salmonella vaccine strains as a carboxy-terminal fusion to fragment C of tetanus toxin (TetC). This study demonstrates that antibodies tha
Autor:
Shiu-Shing Soo, C. M. Anjam Khan, C E Hormaeche, Jenefer M. Blackwell, Bernardo Villarreal-Ramos
Publikováno v:
Infection and Immunity. 66:1910-1917
Attenuated strains of Salmonella typhimurium have been widely used as vehicles for delivery and expression of vaccine antigens in murine models of infectious disease. In mice, early bacterial replication following infection with S. typhimurium is con
Publikováno v:
Scopus-Elsevier
Athymic (nu/nu) BALB/c mice and their euthymic (nu/+) littermates were inoculated intravenously with live attenuated vaccine strains of Salmonella typhimurium. All strains caused progressive infections in the athymic mice but not in their euthymic li
Publikováno v:
Molecular Microbiology. 19:791-801
Multiple tandem copies of an immunogenic epitope comprising amino acids 8-23 of glycoprotein D of herpes simplex virus (HSV) were expressed as C-terminal fusions to tetanus toxin fragment C (TetC) in different Salmonella typhimurium live vaccine stra