Zobrazeno 1 - 10
of 162
pro vyhledávání: '"E, Ghayad"'
HSV-1 cellular model reveals links between aggresome formation and early step of Alzheimer’s disease
Autor:
Marie Alexandra Albaret, Julien Textoris, Bastien Dalzon, Jérémy Lambert, Morgane Linard, Catherine Helmer, Sabine Hacot, Sandra E. Ghayad, Martial Ferréol, Hichem C. Mertani, Jean-Jacques Diaz
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Many studies highlight the potential link between the chronic degenerative Alzheimer’s disease and the infection by the herpes simplex virus type-1 (HSV-1). However, the molecular mechanisms making possible this HSV-1-dependent process rem
Externí odkaz:
https://doaj.org/article/1039b9bf4bfc4c8cb63a68facbaa9294
Autor:
Farah Ramadan, Raya Saab, Nader Hussein, Philippe Clézardin, Pascale A. Cohen, Sandra E. Ghayad
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Rhabdomyosarcoma (RMS) is a soft tissue sarcoma of skeletal muscle differentiation, with a predominant occurrence in children and adolescents. One of the major challenges facing treatment success is the presence of metastatic disease at the time of d
Externí odkaz:
https://doaj.org/article/e924c34e183d4d2db6724a83dd530c7f
Autor:
Farah Ghamloush, Sandra E. Ghayad, Ghina Rammal, Assil Fahs, Abeer J. Ayoub, Zeina Merabi, Mohamad Harajly, Hassan Zalzali, Raya Saab
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. The alveolar subtype (ARMS) is clinically more aggressive, and characterized by an oncogenic fusion protein PAX3-FOXO1 that drives oncogenic cellular properties. Exos
Externí odkaz:
https://doaj.org/article/48ff41dea4bf4d4aae9196741925086f
Autor:
Abeer J. Ayoub, Layal Hariss, Nehme El-Hachem, Ghewa A. El-Achkar, Sandra E. Ghayad, Oula K. Dagher, Nada Borghol, René Grée, Bassam Badran, Ali Hachem, Eva Hamade, Aida Habib
Publikováno v:
BMC Chemistry, Vol 13, Iss 1, Pp 1-18 (2019)
Abstract Introduction New fluorinated diaryl ethers and bisarylic ketones were designed and evaluated for their anti-inflammatory effects in primary macrophages. Methods The synthesis of the designed molecules started from easily accessible and versa
Externí odkaz:
https://doaj.org/article/84a342bf0b0e458f804a0b73c9bae9a6
Autor:
Assil Fahs, Nader Hussein, Hasan Zalzali, Farah Ramadan, Farah Ghamloush, Hani Tamim, Mahmoud El Homsi, Bassam Badran, Fouad Boulos, Ayman Tawil, Sandra E. Ghayad, Raya Saab
Publikováno v:
Cells, Vol 11, Iss 15, p 2267 (2022)
Rhabdomyosarcoma (RMS) is an aggressive childhood soft-tissue tumor, with propensity for local invasion and distant metastasis. Exosomes are secreted vesicles that mediate paracrine signaling by delivering functional proteins and miRNA to recipient c
Externí odkaz:
https://doaj.org/article/7b3ff9f5a340434ea268da553f4623ee
Autor:
Assil Fahs, Farah Ramadan, Farah Ghamloush, Abeer J. Ayoub, Fatima Ali Ahmad, Firas Kobeissy, Yehia Mechref, Jingfu Zhao, Rui Zhu, Nader Hussein, Raya Saab, Sandra E. Ghayad
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Rhabdomyosarcoma (RMS) is a highly malignant soft tissue sarcoma classified into two major histologic subtypes: embryonal (ERMS) and alveolar (ARMS). ARMS subtype is clinically more aggressive, and characterized by an oncogenic fusion protein PAX3-FO
Externí odkaz:
https://doaj.org/article/25e0cb3727ab424e897aa97eadce06a3
Autor:
Caterina F. Donini, Myriam El Helou, Anne Wierinckx, Balázs Győrffy, Sophie Aires, Aurélie Escande, Séverine Croze, Philippe Clezardin, Joël Lachuer, Mona Diab-Assaf, Sandra E. Ghayad, Béatrice Fervers, Vincent Cavaillès, Véronique Maguer-Satta, Pascale A. Cohen
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
It is of utmost importance to decipher the role of chronic exposure to low doses of environmental carcinogens on breast cancer progression. The early-transformed triple-negative human mammary MCF10AT1 cells were chronically (60 days) exposed to low d
Externí odkaz:
https://doaj.org/article/9deef468b8a74ab58e8ea72c1647ba1c
Autor:
Habib, Abeer J. Ayoub, Ghewa A. El-Achkar, Sandra E. Ghayad, Layal Hariss, Razan H. Haidar, Leen M. Antar, Zahraa I. Mallah, Bassam Badran, René Grée, Ali Hachem, Eva Hamade, Aida
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10399
Benzofuran and 2,3-dihydrobenzofuran scaffolds are heterocycles of high value in medicinal chemistry and drug synthesis. Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the present study, we investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::430e376281b05a0588cbb4793c08d881
Autor:
Pascale A. Cohen, Ruth Rimokh, Isabelle Treilleux, Laura Corbo, Pierre Roux, Jean-Luc Coll, Véronique Josserand, Evelyne Grisard, Ivan Bièche, Stéphanie Vinot, Sandra E. Ghayad, Nhan T. Nguyen, Aurélie Thollet, Julie A. Vendrell
The Krüppel-like zinc finger protein ZNF217 is a candidate oncogene in breast cancer. In this study, we showed that high levels of expression of ZNF217 mRNA are associated with poor prognosis and the development of metastases in breast cancer. Overe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e987af4e429c7caf612f914a9fa057f8
https://doi.org/10.1158/0008-5472.c.6503309.v1
https://doi.org/10.1158/0008-5472.c.6503309.v1
Autor:
Pascale A. Cohen, Ruth Rimokh, Isabelle Treilleux, Laura Corbo, Pierre Roux, Jean-Luc Coll, Véronique Josserand, Evelyne Grisard, Ivan Bièche, Stéphanie Vinot, Sandra E. Ghayad, Nhan T. Nguyen, Aurélie Thollet, Julie A. Vendrell
PDF file - 3.2MB, complementary figures showing the impact of ZNF217 overexpression on MDA-MB-231 and HMLE cells phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8aab2b60d835876c2754efa1e20650
https://doi.org/10.1158/0008-5472.22391636
https://doi.org/10.1158/0008-5472.22391636