Zobrazeno 1 - 10
of 320
pro vyhledávání: '"E, Głowacka"'
Publikováno v:
Farmacja Polska, Vol 79, Iss 12, Pp 789-800 (2024)
Alzheimer’s disease (AD) is a neurodegenerative disorder. Although the first case of Alzheimer’s disease was recorded over a century ago, the etiology of the disease remains unknown. There are several hypotheses regarding the process of neurodege
Externí odkaz:
https://doaj.org/article/452bebf2419e4139a0ae076147cd942a
Autor:
Katarzyna Gawron, Dorota G. Piotrowska, Graciela Andrei, Dominique Schols, Robert Snoeck, Iwona E. Głowacka
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 5, Pp 775-793 (2023)
A new series of N-(diethylphosphonoalkyl)-1,8-naphthalimides were synthesized via direct reaction of 1,8-naphthalic anhydride or its 3-nitro- and 4-bromo- derivatives with selected ɷ-aminoalkylphosphonates and evaluated against a broad-spectrum of v
Externí odkaz:
https://doaj.org/article/a5f9cdde73cf449e91a9bca8ad2a9f15
Autor:
Magdalena Łysakowska, Iwona E. Głowacka, Ewelina Honkisz-Orzechowska, Jadwiga Handzlik, Dorota G. Piotrowska
Publikováno v:
Molecules, Vol 29, Iss 13, p 3050 (2024)
In this study, a new series of cis and trans 5-substituted-3-(dibenzyloxyphosphoryl)isoxazolidines 16a–g were synthesized by the 1,3-dipolar cycloaddition reaction of N-benzyl-C-(dibenzyloxyphosphoryl)nitrone and selected N1-allyl-N3-benzylquinazol
Externí odkaz:
https://doaj.org/article/b6bb75c24596445f9790ed339e54bf83
Publikováno v:
Molecules, Vol 28, Iss 3, p 1466 (2023)
Simple and efficient strategies for the syntheses of enantiomerically enriched functionalized diethyl 2-amino-, 2,3-diamino- and 2-amino-3-hydroxypropylphosphonates have been developed starting from, respectively, N-protected (aziridin-2-yl)methylpho
Externí odkaz:
https://doaj.org/article/006e6ab7e68e41948e5565cf7034a378
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 36 (2022)
Herein, we report the synthesis and antioxidant capacity of twelve novel 1,2,3-triazole-containing nitrones such as N-(2-(4-aryl-1H-1,2,3-triazol-1-yl)ethylidene)methanamine oxides 8a–f and N-(2-(4-aryl)-1H-1,2,3-triazol-1-yl)ethylidene)-2-methylpr
Externí odkaz:
https://doaj.org/article/71b8d4f1c1ed4ac9af48c432f07963cd
Autor:
Magdalena Łysakowska, Iwona E. Głowacka, Graciela Andrei, Dominique Schols, Robert Snoeck, Paweł Lisiecki, Magdalena Szemraj, Dorota G. Piotrowska
Publikováno v:
Molecules, Vol 27, Iss 19, p 6526 (2022)
Dipolar cycloaddition of the N-substituted C-(diethoxyphosphonyl)nitrones with N3-allyl-N1-benzylquinazoline-2,4-diones produced mixtures of diastereoisomeric 3-(diethoxyphosphonyl)isoxazolidines with a N1-benzylquinazoline-2,4-dione unit at C5. The
Externí odkaz:
https://doaj.org/article/8b6be0e2e6704e748d8d5ae29adf2ad9
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1722-1757 (2019)
Since Garner’s aldehyde has several drawbacks, first of all is prone to racemization, alternative three-carbon chirons would be of great value in enantioselective syntheses of natural compounds and/or drugs. This review article summarizes applicati
Externí odkaz:
https://doaj.org/article/e3f96b7f57b44000abda0281f4c8d9c3
Autor:
Dorota G. Piotrowska, Laura Mediavilla, Leticia Cuarental, Iwona E. Głowacka, José Marco-Contelles, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, María Jesús Oset-Gasque
Publikováno v:
ACS Omega, Vol 4, Iss 5, Pp 8581-8587 (2019)
Externí odkaz:
https://doaj.org/article/600d6d1c337f48cf9ef9471ab8a67cdf
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 236-255 (2019)
Glutamic acid is involved in several cellular processes though its role as the neurotransmitter is best recognized. For detailed studies of interactions with receptors a number of structural analogues of glutamic acid are required to map their active
Externí odkaz:
https://doaj.org/article/435fe3d229be48a995a336981df800b5
Publikováno v:
Molecules, Vol 27, Iss 9, p 2699 (2022)
All the enantiomers of (1-amino-3-hydroxypropane-1,3-diyl)diphosphonic acid, newly design phosphonate analogues of 4-hydroxyglutamic acids, were obtained. The synthetic strategy involved Abramov reactions of diethyl (R)- and (S)-1-(N-Boc-amino)-3-oxo
Externí odkaz:
https://doaj.org/article/dc94645723c747e3ba7825f174e4bba2