Zobrazeno 1 - 10
of 1 042
pro vyhledávání: '"E, Egan"'
Autor:
Ravindra Gudneppanavar, Caterina Di Pietro, Hasan H Öz, Ping-Xia Zhang, Ee-Chun Cheng, Pamela H. Huang, Toma Tebaldi, Giulia Biancon, Stephanie Halene, Adam D. Hoppe, Catherine Kim, Anjelica L. Gonzalez, Diane S. Krause, Marie E. Egan, Neetu Gupta, Thomas S. Murray, Emanuela M. Bruscia
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-17 (2024)
Abstract Ezrin, an actin-binding protein, orchestrates the organization of the cortical cytoskeleton and plasma membrane during cell migration, adhesion, and proliferation. Its role in monocytes/macrophages (MΦs) is less understood. Here, we used a
Externí odkaz:
https://doaj.org/article/a14808cb3fb24df6a2ce87b009fee579
Autor:
Nandini Raghuram, E. Idil Temel, Toshihiro Kawamata, Katelyn J. Kozma, Amanda J. Loch, Wei Wang, Jessica R. Adams, William J. Muller, Sean E. Egan
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-12 (2024)
Abstract Copy number gains in genes coding for Rho activating exchange factors as well as losses affecting genes coding for RhoGAP proteins are common in breast cancer (BC), suggesting that elevated Rho signaling may play an important role. Extra cop
Externí odkaz:
https://doaj.org/article/9bb3dfba366749538f9812dc3140b0b5
Autor:
Alexandra S. Piotrowski-Daspit, Laura G. Bracaglia, David A. Eaton, Owen Richfield, Thomas C. Binns, Claire Albert, Jared Gould, Ryland D. Mortlock, Marie E. Egan, Jordan S. Pober, W. Mark Saltzman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The in vivo efficacy of polymeric nanoparticles (NPs) is dependent on their pharmacokinetics, including time in circulation and tissue tropism. Here we explore the structure-function relationships guiding physiological fate of a library of p
Externí odkaz:
https://doaj.org/article/1fd79750bbb044449ad583ead8cb54cf
Autor:
G. Bastille‐Rousseau, S. A. Crews, E. B. Donovan, M. E. Egan, N. T. Gorman, J. B. Pitman, A. M. Weber, E. M. Audia, M. R. Larreur, H. Manninen, S. Blake, M. W. Eichholz, E. Bergman, N. D. Rayl
Publikováno v:
Methods in Ecology and Evolution, Vol 15, Iss 2, Pp 345-357 (2024)
Abstract The intensity of use of a location is one of the most studied properties of animal movement, yet movement analyses generally focus on the overall use of a location without much consideration of how patterns in intensity of use emerge. Extrac
Externí odkaz:
https://doaj.org/article/56da2701bdc347758386050e2d5470d5
Autor:
Zhe Jiang, YoungJun Ju, Amjad Ali, Philip E. D. Chung, Patryk Skowron, Dong-Yu Wang, Mariusz Shrestha, Huiqin Li, Jeff C. Liu, Ioulia Vorobieva, Ronak Ghanbari-Azarnier, Ethel Mwewa, Marianne Koritzinsky, Yaacov Ben-David, James R. Woodgett, Charles M. Perou, Adam Dupuy, Gary D. Bader, Sean E. Egan, Michael D. Taylor, Eldad Zacksenhaus
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Metastatic breast-cancer is a major cause of death in women worldwide, yet the relationship between oncogenic drivers that promote metastatic versus primary cancer is still contentious. To elucidate this relationship in treatment-naive anima
Externí odkaz:
https://doaj.org/article/141fc3ada18346a59e6af3fd9ea5bbbb
Autor:
Michael E. Egan, Kim M. Pepin, Justin W. Fischer, Scott E. Hygnstrom, Kurt C. VerCauteren, Guillaume Bastille‐Rousseau
Publikováno v:
Ecosphere, Vol 14, Iss 2, Pp n/a-n/a (2023)
Abstract Host contact structure affects pathogen transmission in host populations, but many measures of host contact do not distinguish contacts that are relevant to pathogen transmission from those that are not. Scrapes are sites for chemical commun
Externí odkaz:
https://doaj.org/article/905d10b5e11d47f0b27265f2b4dabefe
Autor:
Jacques Greenberg, Jessica Limberg, Akanksha Verma, David Kim, Xiang Chen, Yeon J. Lee, Maureen D. Moore, Timothy M. Ullmann, Jessica W. Thiesmeyer, Zachary Loewenstein, Kevin J. Chen, Caitlin E. Egan, Dessislava Stefanova, Rohan Bareja, Rasa Zarnegar, Brendan M. Finnerty, Theresa Scognamiglio, Yi-Chieh Nancy Du, Olivier Elemento, Thomas J. Fahey III, Irene M. Min
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Pancreatic neuroendocrine tumors (PNETs) are malignancies arising from the islets of Langerhans. Therapeutic options are limited for the over 50% of patients who present with metastatic disease. We aimed to identify mechanisms to remodel the PNET tum
Externí odkaz:
https://doaj.org/article/6f96a988d4f44b32a06c2793e68c3f00
Autor:
Michael M. Kaiser, Brett E. Egan
In the third book of his popular trilogy on creating and sustaining arts organizations, Michael Kaiser reveals the hidden engine that powers consistent success. According to Kaiser, successful arts organizations pursue strong programmatic marketing c
Autor:
Nathan F. Schachter, Jessica R. Adams, Patryk Skowron, Katelyn. J. Kozma, Christian A. Lee, Nandini Raghuram, Joanna Yang, Amanda J. Loch, Wei Wang, Aaron Kucharczuk, Katherine L. Wright, Rita M. Quintana, Yeji An, Daniel Dotzko, Jennifer L. Gorman, Daria Wojtal, Juhi S. Shah, Paul Leon-Gomez, Giovanna Pellecchia, Adam J. Dupuy, Charles M. Perou, Ittai Ben-Porath, Rotem Karni, Eldad Zacksenhaus, Jim R. Woodgett, Susan J. Done, Livia Garzia, A. Sorana Morrissy, Jüri Reimand, Michael D. Taylor, Sean E. Egan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Transposon based screens carried out in mice can identify genes critical for tumourigensis. Here, the authors describe transposon screens in mouse models of breast cancer and highlight a large group of tumour suppressors that could underlie selection
Externí odkaz:
https://doaj.org/article/7b80ad2dd67744ecb57557946c051bff
Autor:
Lan Yu, Janet M Turan, Emma Sophia Kay, Stephanie Creasy, D Scott Batey, Robert Coulter, James E Egan, Stuart Fisk, Mackey Reuel Friedman, Suzanne Kinsky, Sarah Krier, Victor Noble, Bulent Turan, Mary Hawk
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Introduction Our previous pilot work suggests relational harm reduction strengthens relationships between people with HIV (PWH) who use drugs and their healthcare providers and improves HIV health outcomes. However, there is limited research examinin
Externí odkaz:
https://doaj.org/article/b07505f61a4a44cab4aca76538af4c35