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Publikováno v:
The Journal of Immunology. 158:1503-1506
To explore the possibility that CD4+ T cells, described to mediate the elimination of themselves or B lymphocytes, could also mediate the elimination of CD8+ T cells, we analyzed apoptotic phenomena in cocultures of CD4+ and CD8+ autologous T cell li
Autor:
E. Cundari, R. Ricordy, Mario Fiore, Italo Poggesi, A. Esposito, Gabriella Augusti-Tocco, G. Scarsella, Roberto Ceccarelli, P. Paggi, L. Satta
Publikováno v:
Mutation Research Letters. 347:129-133
Background radiation is likely to constitute one of the factors involved in biological evolution since radiations are able to affect biological processes. Therefore, it is possible to hypothesize that organisms are adapted to environmental background
Publikováno v:
European Journal of Immunology. 24:1061-1065
We present evidence that dexamethasone (Dex), a synthetic glucocorticosteroid, causes apoptosis in mature human T cells, similarly to what has been reported for murine T lymphocytes. Human T cell clones and short-term activated T lymphocytes treated
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 11(8)
Ran-binding protein (RanBP) 1 is a major regulator of the Ran GTPase and is encoded by a regulatory target gene of E2F factors. The Ran GTPase network controls several cellular processes, including nucleocytoplasmic transport and cell cycle progressi
Publikováno v:
Cancer research. 57(9)
Fanconi anemia (FA) is a genetic human disorder associated with bone marrow failure and predisposition to cancer. FA cells show poor growth capacity and spontaneous chromosomal anomalies as well as cellular and chromosomal hypersensitivity to DNA cro
Autor:
S. Lorenzetti, E. Cundari, S. Moretti, Giovanna Lombardi, Enza Piccolella, Loretta Tuosto, M. S. Gilardini Montani
To support the hypothesis that indirect mechanisms mediated by viral products like the HIV envelope glycoprotein gp120 could be responsible for T lymphocyte depletion in HIV infection, we developed a system in which the impairment of T cell functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2459d9c11d3c199897ebb495d6ed1cd
http://hdl.handle.net/11573/783370
http://hdl.handle.net/11573/783370
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 317(11)
Ataxia-telangiectasia is a progressive recessive disease featuring neurodegeneration, immunodeficiency, chromosomal instability, radiation hypersensitivity and increased predisposition to cancer. Impaired induction of the tumor suppressor protein p53
Autor:
G. Lombardi, Xin Ting Fu, Enza Piccolella, R W Karr, Loretta Tuosto, Robert I. Lechler, Richard R. Olson, E. Cundari
The contributions of individual amino acids in the polymorphic beta chain and the conserved alpha chain of HLA-DR1 to influenza HA-specific DR1-restricted and anti-DR1 allospecific T-cell recognition were analyzed. The genes encoding HLA-DR1 were sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf5712a6ff1a2b158124e290ab2a245
http://hdl.handle.net/11573/129962
http://hdl.handle.net/11573/129962
Autor:
Vincenzo Mollace, Renato Massoud, Giuseppe Nisticò, Giuliana M. Lauro, Marco Colasanti, E. Cundari
Publikováno v:
International journal of immunopharmacology. 15(6)
The effects of interferon gamma (gamma IFN) on the MHCII antigen expression by human cultured astrocytoma cells were investigated. The co-incubation of gamma IFN with T67 astrocytoma cells produced a dose-dependent increase of MHCII antigen expressio