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pro vyhledávání: '"E, Boldt"'
Publikováno v:
Journal of Hydrology: Regional Studies, Vol 19, Iss , Pp 164-176 (2018)
Study region: Santa Ynez River Basin, Santa Barbara County, California. Study focus: Lake Cachuma, a reservoir on the Santa Ynez River, provides water for over 280,000 residents and agricultural lands of Santa Barbara County, California. This area ex
Externí odkaz:
https://doaj.org/article/c558f2c37b7b49afbd40936c1572a1f1
Publikováno v:
Journal of Hydrology: Regional Studies, Vol 19, Iss, Pp 164-176 (2018)
Study region: Santa Ynez River Basin, Santa Barbara County, California. Study focus: Lake Cachuma, a reservoir on the Santa Ynez River, provides water for over 280,000 residents and agricultural lands of Santa Barbara County, California. This area ex
Akademický článek
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Akademický článek
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Autor:
Alicia Izharrudin, Jorge Nieva, Rajesh K. Grover, Byeong Doo Song, Paul Wentworth, Anita D. Wentworth, Joseph K. Rogel, Grant E. Boldt, David Kujawara, Lawrence Altobel
Publikováno v:
Chemistry & Biology. 18(7):920-927
Summary Epidemiologic and clinical evidence points to an increased risk for cancer when coupled with chronic inflammation. However, the molecular mechanisms that underpin this interrelationship remain largely unresolved. Herein we show that the infla
Publikováno v:
Angewandte Chemie. 121:9633-9636
Autor:
Robert L. Walsky, Sherri E Boldt
Publikováno v:
Current Drug Metabolism. 9:928-939
The assessment of in vitro inhibition and induction of the cytochrome P450 enzymes of the liver is a critical part of the drug discovery and development process in order to ensure that two or more drugs can be safely coadministered without alteration
Publikováno v:
Angewandte Chemie. 120:3983-3986
Autor:
Kim D. Janda, Jack P. Kennedy, Saul Tzipori, Mark S. Hixon, Karen N. Allen, Nicholas R. Silvaggi, Grant E. Boldt
Publikováno v:
Chemistry & Biology. 14:533-542
SummaryThe potential for the use of Clostridial neurotoxins as bioweapons makes the development of small-molecule inhibitors of these deadly toxins a top priority. Recently, screening of a random hydroxamate library identified a small-molecule inhibi
Autor:
Laura A. McAllister, Jack P. Kennedy, Noboru Yamamoto, Xuxia Yan, Shibo Jiang, Jason A. Moss, Kim D. Janda, Grant E. Boldt, Yang Xu, Hong Lu
Publikováno v:
Journal of Combinatorial Chemistry. 8:531-539
Protein-protein interactions are of critical importance in biological systems and small molecule modulators of such protein recognition and intervention processes are of particular interests. To investigate this area of research, we have synthesized