Zobrazeno 1 - 10
of 621
pro vyhledávání: '"E, Birk"'
Autor:
Mengjie Zhu, Fabian Metzen, Mark Hopkinson, Janina Betz, Juliane Heilig, Jassi Sodhi, Thomas Imhof, Anja Niehoff, David E. Birk, Yayoi Izu, Marcus Krüger, Andrew A. Pitsillides, Janine Altmüller, Gerjo J.V.M. van Osch, Volker Straub, Gudrun Schreiber, Mats Paulsson, Manuel Koch, Bent Brachvogel
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107225- (2023)
Summary: Collagen XII, belonging to the fibril-associated collagens, is a homotrimeric secreted extracellular matrix (ECM) protein encoded by the COL12A1 gene. Mutations in the human COL12A1 gene cause an Ehlers-Danlos/myopathy overlap syndrome leadi
Externí odkaz:
https://doaj.org/article/9b9be6f40bdd4d2e8ab523d6005f0342
Autor:
Yayoi Izu, David E. Birk
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Collagen XII, a fibril-associated collagen with interrupted triple helices (FACIT), influences fibrillogenesis in numerous tissues. In addition to this extracellular function, collagen XII also directly regulates cellular function. Collagen XII is wi
Externí odkaz:
https://doaj.org/article/192d0e699eb94385b5403d8a0281cfd1
Publikováno v:
Matrix Biology Plus, Vol 16, Iss , Pp 100123- (2022)
Collagen XII is a fibril-associated collagen with interrupted triple helices (FACIT). This non-fibrillar collagen is a homotrimer composed of three α1(XII) chains assembled into a collagenous molecule with a C terminal collagenous domain and a large
Externí odkaz:
https://doaj.org/article/ddd609a90dc6404d9795319deeef9cba
Autor:
Zakary M. Beach, Mihir S. Dekhne, Ashley B. Rodriguez, Stephanie N. Weiss, Thomas H. Adams, Sheila M. Adams, Mei Sun, David E. Birk, Louis J. Soslowsky
Publikováno v:
Matrix Biology Plus, Vol 15, Iss , Pp 100114- (2022)
Decorin and biglycan are two major small leucine-rich proteoglycans (SLRPs) present in the tendon extracellular matrix that facilitate collagen fibrillogenesis, tissue turnover, and cell signal transduction. Previously, we demonstrated that knockout
Externí odkaz:
https://doaj.org/article/78329dac72374b3ebe73282ada16ec88
Autor:
Ryan J. Leiphart, Hai Pham, Tyler Harvey, Taishi Komori, Tina M. Kilts, Snehal S. Shetye, Stephanie N. Weiss, Sheila M. Adams, David E. Birk, Louis J. Soslowsky, Marian F. Young
Publikováno v:
Matrix Biology Plus, Vol 13, Iss , Pp 100099- (2022)
Tendon is a vital musculoskeletal tissue that is prone to degeneration. Proper tendon maintenance requires complex interactions between extracellular matrix components that remain poorly understood. Collagen VI and biglycan are two matrix molecules t
Externí odkaz:
https://doaj.org/article/8ff4cec26ecb461e91a26fcea0bdab01
Autor:
Chang Yeop Han, Inkyung Kang, Ingrid A. Harten, John A. Gebe, Christina K. Chan, Mohamed Omer, Kimberly M. Alonge, Laura J. den Hartigh, Diego Gomes Kjerulf, Leela Goodspeed, Savitha Subramanian, Shari Wang, Francis Kim, David E. Birk, Thomas N. Wight, Alan Chait
Publikováno v:
Cell Reports, Vol 31, Iss 13, Pp 107818- (2020)
Summary: Obesity is characterized by adipose tissue inflammation. Because proteoglycans regulate inflammation, here we investigate their role in adipose tissue inflammation in obesity. We find that adipose tissue versican and biglycan increase in obe
Externí odkaz:
https://doaj.org/article/0ab5266a0eec4194a0bd5b3e2ad576af
Autor:
Tanya Papaz, HBA, Upton Allen, MBBS, Tom Blydt-Hansen, MD, Patricia E. Birk, MD, Sandar Min, MBBS, Lorraine Hamiwka, MD, Veronique Phan, MD, Tal Schechter, MD, Donna A. Wall, MD, Simon Urschel, MD, Bethany J. Foster, MD, Seema Mital, MD
Publikováno v:
Transplantation Direct, Vol 4, Iss 12, p e410 (2018)
Background. Despite age-related differences in biology, physiology, and behavior, transplant immunosuppression is not tailored by age. This likely contributes to high graft failure and posttransplant complications. We present the aims, design, and me
Externí odkaz:
https://doaj.org/article/f65ea14b6bad46348c3f6a125b1a988c
Autor:
Sarah E. Birk, David A. Baran, Robert Campbell, John M. Herre, Hessam Sadatsafavi, Amin Yehya
Publikováno v:
The Journal of Heart and Lung Transplantation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c30d444f995c3b89affa2a6f1d59250
https://doi.org/10.1016/j.healun.2023.04.014
https://doi.org/10.1016/j.healun.2023.04.014
Publikováno v:
European Archives of Oto-Rhino-Laryngology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f675cde15dec0a16dad864cf64733d9
https://doi.org/10.1007/s00405-023-07916-y
https://doi.org/10.1007/s00405-023-07916-y
Autor:
Zakary M. Beach, Kelsey A. Bonilla, Mihir S. Dekhne, Mei Sun, Thomas H. Adams, Sheila M. Adams, Stephanie N. Weiss, Ashley B. Rodriguez, Snehal S. Shetye, David E. Birk, Louis J. Soslowsky
Publikováno v:
Journal of Orthopaedic Research. 40:2546-2556
Decorin and biglycan are two small leucine-rich proteoglycans (SLRPs) that regulate collagen fibrillogenesis and extracellular matrix assembly in tendon. The objective of this study was to determine the individual roles of these molecules in maintain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4f7c47cbc7d6cdea3b5143372d4bfb
https://doi.org/10.1002/jor.25299
https://doi.org/10.1002/jor.25299