Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dzuy T. Nguyen"'
Autor:
Dzuy T. Nguyen, Eleanor F. Howland, S. M. Herrmann, C. A. Morse, Russell J. Bacquet, Jones Terence R, Ward W. Smith, Charlotte A. Bartlett, Stephanie Webber, K. M. Welsh, Cheryl Ann Janson, Kathardekar, M. R. Reddy, Carol L. J. Booth, H. Mazdiyasni, Lewis Kk, J. White, A. Johnston, J. Deal, Stephen E. Webber, David A. Matthews, Robert William Ward, Varney
Publikováno v:
Journal of Medicinal Chemistry. 40:677-683
Six new diphenyl sulfoxide and five new diphenyl sulfones were designed, synthesized, and tested for their inhibition of human and Escherichia coli thymidylate synthase (TS) and of the growth of cells in tissue culture. The best sulfoxide inhibitor o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b00058c01b30433c8d4b3576dc6989
https://doi.org/10.1021/jm960613f
https://doi.org/10.1021/jm960613f
Autor:
Heather Dawson, Mitchell Lennert J, Kathy K. Lewis, Stephanie Webber, Dominic Andrada, B.‐W. Wu, Krzysztof Appelt, Anthony J. Trippe, Dan K. Gehlhaar, Deborah Kahil, Dzuy T. Nguyen, Jay F. Davies, Bhasker V. Shetty, L. Musick, Reich Siegfried Heinz, Melnick Michael J, Maha Kosa
Publikováno v:
Journal of medicinal chemistry. 39(14)
A series of potent nonpeptide inhibitors of the HIV protease have been identified. Using the structure of compound 3 bound to the HIV protease, bis tertiary amide inhibitor 9 was designed and prepared. Compound 9 was found to be about 17 times more p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1292b4b60ff4c638e6b25940f1f41a5
https://pubmed.ncbi.nlm.nih.gov/8709110
https://pubmed.ncbi.nlm.nih.gov/8709110
Autor:
Mary Ann M. Fuhry, Ward W. Smith, David A. Matthews, Katherine M. Welsh, Dzuy T. Nguyen, S R Jordan, Cheryl A. Janson, Siegfried Reich, Mark J. Pino, Stephanie Webber
Publikováno v:
Journal of medicinal chemistry. 35(5)
Antifolate inhibitors of thymidylate synthase (TS) have primarily been based on the structure of folic acid. This paper describes the identification and development of novel 6,7-imidazotetrahydroquinoline TS inhibitors by iterative ligand design, syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3d1e9e44b14d2cc29104d907ec3681
https://pubmed.ncbi.nlm.nih.gov/1548676
https://pubmed.ncbi.nlm.nih.gov/1548676
Autor:
Komatsu, Toshifumi, Urakawa, Ryota, Inada, Toshitaka, Yamauchi, Kazuki, Maekawa, Takumi, Takashima, Reishi, Williams, Mark, Nguyen, Phong D., Doan, Hung D., Nguyen, Minh T., Niko, Shuji, Tanaka, Gengo, Yamaguchi, Tatsuhiko
Publikováno v:
Island Arc; Jan2019, Vol. 28 Issue 1, pN.PAG-N.PAG, 1p