Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Dzmitry Shcharbin"'
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 1, Pp 50-61 (2022)
During the past two decades, tremendous progress has been made in the dendrimer-based delivery of therapeutic molecules including, for instance, small molecules, macromolecules, and genes. This review deals with recent successes in the development of
Externí odkaz:
https://doaj.org/article/f0e3b969222048f0921dbd5d765f20c9
Autor:
Viktar Abashkin, Elżbieta Pędziwiatr-Werbicka, Katarzyna Horodecka, Victoriya Zhogla, Egor Ulashchik, Vadim Shmanai, Dzmitry Shcharbin, Maria Bryszewska
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 840 (2023)
The fact that cancer is one of the leading causes of death requires researchers to create new systems of effective treatment for malignant tumors. One promising area is genetic therapy that uses small interfering RNA (siRNA). These molecules are capa
Externí odkaz:
https://doaj.org/article/38d6a9ce0e6341fbbed27ff49421d4ea
Autor:
Olga Mostovaya, Igor Shiabiev, Dmitry Pysin, Alesia Stanavaya, Viktar Abashkin, Dzmitry Shcharbin, Pavel Padnya, Ivan Stoikov
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2748 (2022)
A convenient method for the synthesis of the second generation of PAMAM dendrimers based on a p-tert-butylthiacalix[4]arene core in cone, partial cone and 1,3-alternate conformations was developed. Unusual fluorescence of the obtained PAMAM-calix-den
Externí odkaz:
https://doaj.org/article/595d8d0ba36b40c7becdbfab51d766e5
Autor:
Huxiao Sun, Mengsi Zhan, Serge Mignani, Dzmitry Shcharbin, Jean-Pierre Majoral, João Rodrigues, Xiangyang Shi, Mingwu Shen
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2239 (2022)
Curcumin (Cur), a traditional Chinese medicine extracted from natural plant rhizomes, has become a candidate drug for the treatment of diseases due to its anti-inflammatory, anticancer, antioxidant, and antibacterial activities. However, the poor wat
Externí odkaz:
https://doaj.org/article/867f8b47a03241c7a80ba7746cbfbbbf
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3996 (2022)
Circulating microRNAs (c-microRNAs, c-miRNAs), which are present in almost all biological fluids, are promising sensitive biomarkers for various diseases (oncological and cardiovascular diseases, neurodegenerative pathologies, etc.), and their signat
Externí odkaz:
https://doaj.org/article/219563ec60aa44ef9f16813fecb3d5e0
Autor:
Simon Suty, Veronika Oravczova, Zuzana Garaiova, Veronika Subjakova, Maksim Ionov, Dzmitry Shcharbin, Zuzana Simonikova, Peter Bartek, Milan Zvarik, Xiangyang Shi, Serge Mignani, Jean-Pierre Majoral, Maria Bryszewska, Tibor Hianik, Iveta Waczulikova
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1672 (2021)
Dendrons are branched synthetic polymers suitable for preparation of nanosized drug delivery systems. Their interactions with biological systems are mainly predetermined by their chemical structure, terminal groups, surface charge, and the number of
Externí odkaz:
https://doaj.org/article/cd2b0dd4cd654d82bd4706b1df56a338
Autor:
Viktar Abashkin, Elżbieta Pędziwiatr-Werbicka, Rafael Gómez, Francisco Javier de la Mata, Volha Dzmitruk, Dzmitry Shcharbin, Maria Bryszewska
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1549 (2021)
Cancer is one of the most important problems of modern medicine. At the present time, gene therapy has been developed against cancer, which includes the delivery of anticancer small interfering RNAs (siRNAs) directed at cancer proteins. The prospect
Externí odkaz:
https://doaj.org/article/a2d730e25fe6499090c6223c241ba7f0
Autor:
Sylwia Michlewska, Maksim Ionov, Aleksandra Szwed, Aneta Rogalska, Natalia Sanz del Olmo, Paula Ortega, Marta Denel, Damian Jacenik, Dzmitry Shcharbin, Francisco Javier de la Mata, Maria Bryszewska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4119 (2020)
Ruthenium atoms located in the surfaces of carbosilane dendrimers markedly increase their anti-tumor properties. Carbosilane dendrimers have been widely studied as carriers of drugs and genes owing to such characteristic features as monodispersity, s
Externí odkaz:
https://doaj.org/article/cde449a09ca94267aa54ce3002fe37af
Autor:
Aleksandra Szwed, Katarzyna Miłowska, Sylwia Michlewska, Silvia Moreno, Dzmitry Shcharbin, Rafael Gomez-Ramirez, Francisco Javier de la Mata, Jean-Pierre Majoral, Maria Bryszewska, Teresa Gabryelak
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 427 (2020)
Dendrimers as drug carriers can be utilized for drugs and siRNA delivery in central nervous system (CNS) disorders, including various types of cancers, such as neuroblastomas and gliomas. They have also been considered as drugs per se, for example as
Externí odkaz:
https://doaj.org/article/3c3be972b7fa45aaa7c0e49899dc609e
Synthesis and Characterization of FITC Labelled Ruthenium Dendrimer as a Prospective Anticancer Drug
Autor:
Sylwia Michlewska, Małgorzata Kubczak, Marta Maroto-Díaz, Natalia Sanz del Olmo, Paula Ortega, Dzmitry Shcharbin, Rafael Gomez Ramirez, Francisco Javier de la Mata, Maksim Ionov, Maria Bryszewska
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 411 (2019)
Metallodendrimers—dendrimers with included metals—are widely investigated as biocompatible equivalents to metal nanoparticles. Applications can be expected in the fields of catalysis, as chemical sensors in molecular recognition and as anticancer
Externí odkaz:
https://doaj.org/article/bae4f49c57e7458ab7d784d67995924b