Complex formation with protamine prolongs the thrombin-inhibiting effect of DNA aptamer in vivo.

Autor: Spiridonova VA; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia. Electronic address: spiridon@belozersky.msu.ru., Novikova TM; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia., Nikulina DM; Astrakhan State Medical University Ministry of Public Health of the Russian Federation, Astrakhan, Russia., Shishkina TA; Astrakhan State Medical University Ministry of Public Health of the Russian Federation, Astrakhan, Russia., Golubkina EV; Astrakhan State Medical University Ministry of Public Health of the Russian Federation, Astrakhan, Russia., Dyukareva OS; Astrakhan State Medical University Ministry of Public Health of the Russian Federation, Astrakhan, Russia., Trizno NN; Astrakhan State Medical University Ministry of Public Health of the Russian Federation, Astrakhan, Russia.

Publikováno v: Biochimie [Biochimie] 2018 Feb; Vol. 145, pp. 158-162. Date of Electronic Publication: 2017 Sep 19.