Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Dysoley, Lek"'
Autor:
Dysoley Lek, Nguon Sokomar, Top Samphornarann, Jeanne Rideout, Saad El-Din Hassan, Tol Bunkea, Saing Sam Ath, Rothpisey Seng, John Hustedt, Thomas J. Peto, Jayme Hughes, Ke Kimmen, Khoy Dy, Bipin Adhikari
Publikováno v:
Tropical Medicine and Health, Vol 52, Iss 1, Pp 1-9 (2024)
Abstract Introduction The national malaria programme of Cambodia targets the rapid elimination of all human malaria by 2025. As clinical cases decline to near-elimination levels, a key strategy is the rapid identification of malaria outbreaks trigger
Externí odkaz:
https://doaj.org/article/a145482b60ce43cabc2a2f16a78e5416
Autor:
John Kane, Xue Li, Sudhir Kumar, Katrina A. Button-Simons, Katelyn M. Vendrely Brenneman, Haley Dahlhoff, Mackenzie A. C. Sievert, Lisa A. Checkley, Douglas A. Shoue, Puspendra P. Singh, Biley A. Abatiyow, Meseret T. Haile, Shalini Nair, Ann Reyes, Rupam Tripura, Thomas J. Peto, Dysoley Lek, Angana Mukherjee, Stefan H. I. Kappe, Mehul Dhorda, Standwell C. Nkhoma, Ian H. Cheeseman, Ashley M. Vaughan, Timothy J. C. Anderson, Michael T. Ferdig
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Piperaquine (PPQ) is widely used in combination with dihydroartemisinin as a first-line treatment against malaria. Multiple genetic drivers of PPQ resistance have been reported, including mutations in the Plasmodium falciparum chloroquine re
Externí odkaz:
https://doaj.org/article/b191e5641f084dea867745f9b4a6c1b8
Autor:
Dysoley Lek, Yu-Cheng Tsai, Jillian Hirano, Siv Sovannaroth, Voeurng Bunreth, Prak Vonn, Or Vannthen, Tol Bunkea, Top Samphornarann, Nguon Sokomar, Mak Sarath, Soy Ty Kheang, Evelyn Wong, Michelle K. Burbach, Jayme Hughes, Huy Rekol
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Cambodia aims to eliminate all forms of malaria by 2025. In 2020, 90% of all malaria cases were Plasmodium vivax. Thus, preventing P. vivax and relapse malaria is a top priority for elimination. 14-day primaquine, a World Health O
Externí odkaz:
https://doaj.org/article/2c7c141c70024d6f81d5a5f299896045
Autor:
Mathilde Grimée, Costanza Tacoli, Mirco Sandfort, Thomas Obadia, Aimee R. Taylor, Amélie Vantaux, Leanne J. Robinson, Dysoley Lek, Rhea J. Longley, Ivo Mueller, Jean Popovici, Michael T. White, Benoît Witkowski
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Over the last decades, the number of malaria cases has drastically reduced in Cambodia. As the overall prevalence of malaria in Cambodia declines, residual malaria transmission becomes increasingly fragmented over smaller remote r
Externí odkaz:
https://doaj.org/article/c12ecb854bd64b19b26118c1d6c8b064
Autor:
Freek de Haan, Chanaki Amaratunga, Van Anh Cao Thi, Long Heng Orng, Manithong Vonglokham, Thieu Nguyen Quang, Dysoley Lek, Wouter P. C. Boon, Arjen M. Dondorp, Ellen H. M. Moors
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background This is a qualitative study to identify implementation challenges for deploying triple artemisinin-based combination therapy (TACT) in the Greater Mekong Subregion (GMS) of Southeast Asia and to explore strategies to overcome thes
Externí odkaz:
https://doaj.org/article/526225ade12843e383855c84cd96d85c
Autor:
Sarah A Cassidy-Seyoum, Keoratha Chheng, Phal Chanpheakdey, Agnes Meershoek, Michelle S Hsiang, Lorenz von Seidlein, Rupam Tripura, Bipin Adhikari, Benedikt Ley, Ric N Price, Dysoley Lek, Nora Engel, Kamala Thriemer
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 7, p e0003476 (2024)
Plasmodium vivax remains a challenge for malaria elimination since it forms dormant liver stages (hypnozoites) that can reactivate after initial infection. 8-aminoquinolone drugs kill hypnozoites but can cause severe hemolysis in individuals with Glu
Externí odkaz:
https://doaj.org/article/b899c555495b4fda90cbd9ac7dfc78e2
Autor:
Dyna Doum, David J. Mclver, John Hustedt, Jeffrey Hii, Siv Sovannaroth, Dysoley Lek, Jason H. Richardson, Allison Tatarsky, Neil F. Lobo
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background Malaria is a mosquito-borne disease that is one of the most serious public health issues globally and a leading cause of mortality in many developing countries worldwide. Knowing the prevalence of both symptomatic and asymptomatic
Externí odkaz:
https://doaj.org/article/c4c92cc22bbb46c0ac6a83c7603a642b
Autor:
Dysoley, Lek1,2 (AUTHOR) soleycnm@gmail.com, Callery, James J.3,4 (AUTHOR), Bunreth, Voeurng5 (AUTHOR), Vanna, Moul6 (AUTHOR), Davoeung, Chan5 (AUTHOR), Sovann, Yok7 (AUTHOR), You, Sles5 (AUTHOR), Ol, Sam6,8 (AUTHOR), Tripura, Rupam3,4 (AUTHOR), Chew, Rusheng3,4,9 (AUTHOR), Chandna, Arjun4,10 (AUTHOR), Christiansen-Jucht, Céline11 (AUTHOR), Hughes, Jayme12 (AUTHOR), Sokomar, Nguon13,14,15 (AUTHOR), Sophornarann, Top13,14,15 (AUTHOR), Rideout, Jeanne13,14,15 (AUTHOR), Veyvath, Tat5 (AUTHOR), Sarith, Oum7 (AUTHOR), Puthy, Thaung5 (AUTHOR), Sothearoth, Hay5 (AUTHOR)
Publikováno v:
Malaria Journal. 1/2/2024, Vol. 23 Issue 1, p1-10. 10p.
Autor:
Dysoley Lek, Agus Rachmat, Dustin Harrison, Geoffrey Chin, Suwanna Chaoratanakawee, David Saunders, Didier Menard, William O. Rogers
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract Background Anti-malarial resistance remains an important public health challenge in Cambodia. The effectiveness of three therapies for uncomplicated falciparum malaria was evaluated in Oddar Meanchey province in Northern Cambodia from 2009 t
Externí odkaz:
https://doaj.org/article/e2910843bfe04e7b95aafa4cbbf51a08
Autor:
Adhikari, Bipin, Tripura, Rupam, Peto, Thomas J., Callery, James J., von Seidlein, Lorenz, Dysoley, Lek, Dondorp, Arjen M.
Publikováno v:
In The Lancet Regional Health - Southeast Asia February 2023 9