Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dyneins / metabolism"'
Autor:
Chen, Fangrui, Wu, Jingchao, Iwanski, Malina K, Jurriens, Daphne, Sandron, Arianna, Pasolli, Milena, Puma, Gianmarco, Kromhout, Jannes Z, Yang, Chao, Nijenhuis, Wilco, Kapitein, Lukas C, Berger, Florian, Akhmanova, Anna, Sub Cell Biology, Celbiologie
Publikováno v:
eLife, 11, 1. eLife Sciences Publications
The major microtubule-organizing center (MTOC) in animal cells, the centrosome, comprises a pair of centrioles surrounded by pericentriolar material (PCM), which nucleates and anchors microtubules. Centrosome assembly depends on PCM binding to centri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d721625e04a8e1b05de1c6593805c9f
https://doi.org/10.7554/elife.77892
https://doi.org/10.7554/elife.77892
Autor:
Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel, Julie Talbot, Daniel Picard, Nan Qin, Gabriele Cancila, Qingsong Gao, Soumav Nath, Idriss Mahoungou Koumba, Marietta Wolter, François Kuonen, Maike Langini, Thomas Beez, Christopher Munoz, David Pauck, Viktoria Marquardt, Hua Yu, Judith Souphron, Mascha Korsch, Christina Mölders, Daniel Berger, Sarah Göbbels, Frauke-Dorothee Meyer, Björn Scheffler, Barak Rotblat, Sven Diederichs, Vijay Ramaswamy, Hiromishi Suzuki, Anthony Oro, Kai Stühler, Anja Stefanski, Ute Fischer, Gabriel Leprivier, Dieter Willbold, Gerhard Steger, Alexander Buell, Marcel Kool, Peter Lichter, Stefan M. Pfister, Paul A. Northcott, Michael D. Taylor, Arndt Borkhardt, Guido Reifenberger, Olivier Ayrault, Marc Remke
Publikováno v:
Nature Communications 13(1), 4061 (2022). doi:10.1038/s41467-022-31574-z
Nature communications, vol. 13, no. 1, pp. 4061
Bartl, J, Zanini, M, Bernardi, F, Forget, A, Blümel, L, Talbot, J, Picard, D, Qin, N, Cancila, G, Gao, Q, Nath, S, Koumba, I M, Wolter, M, Kuonen, F, Langini, M, Beez, T, Munoz, C, Pauck, D, Marquardt, V, Yu, H, Souphron, J, Korsch, M, Mölders, C, Berger, D, Göbbels, S, Meyer, F-D, Scheffler, B, Rotblat, B, Diederichs, S, Ramaswamy, V, Suzuki, H, Oro, A, Stühler, K, Stefanski, A, Fischer, U, Leprivier, G, Willbold, D, Steger, G, Buell, A, Kool, M, Lichter, P, Pfister, S M, Northcott, P A, Taylor, M D, Borkhardt, A, Reifenberger, G, Ayrault, O & Remke, M 2022, ' The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors ', Nature Communications, vol. 13, 4061 . https://doi.org/10.1038/s41467-022-31574-z
Nature Communications
Nature Communications, 2022, 13 (1), pp.4061. ⟨10.1038/s41467-022-31574-z⟩
Nature communications, vol. 13, no. 1, pp. 4061
Bartl, J, Zanini, M, Bernardi, F, Forget, A, Blümel, L, Talbot, J, Picard, D, Qin, N, Cancila, G, Gao, Q, Nath, S, Koumba, I M, Wolter, M, Kuonen, F, Langini, M, Beez, T, Munoz, C, Pauck, D, Marquardt, V, Yu, H, Souphron, J, Korsch, M, Mölders, C, Berger, D, Göbbels, S, Meyer, F-D, Scheffler, B, Rotblat, B, Diederichs, S, Ramaswamy, V, Suzuki, H, Oro, A, Stühler, K, Stefanski, A, Fischer, U, Leprivier, G, Willbold, D, Steger, G, Buell, A, Kool, M, Lichter, P, Pfister, S M, Northcott, P A, Taylor, M D, Borkhardt, A, Reifenberger, G, Ayrault, O & Remke, M 2022, ' The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors ', Nature Communications, vol. 13, 4061 . https://doi.org/10.1038/s41467-022-31574-z
Nature Communications
Nature Communications, 2022, 13 (1), pp.4061. ⟨10.1038/s41467-022-31574-z⟩
Most lncRNAs display species-specific expression patterns suggesting that animal models of cancer may only incompletely recapitulate the regulatory crosstalk between lncRNAs and oncogenic pathways in humans. Among these pathways, Sonic Hedgehog (SHH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ec632d06d6284086a564a448ef81a7
https://hdl.handle.net/2128/31691
https://hdl.handle.net/2128/31691
Autor:
Yan Zhou, Heiko Rieger, Mayis Kaba, Varsha Pattu, Rahmad Akbar, Bin Qu, Volkhard Helms, Renping Zhao, Eva C. Schwarz, Paula Nunes-Hasler
Publikováno v:
The journal of immunology, Vol. 205, No 11 (2020) pp. 2988-3000
Delivery of vesicles to their desired destinations plays a central role in maintaining proper cell functionality. In certain scenarios, depending on loaded cargos, the vesicles have spatially distinct destinations. For example, in T cells, some cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17feaa734fdec87f1d78fd2647ad92d
Autor:
Kuijpers, Marijn, van de Willige, Dieudonnée, Freal, Amélie, Chazeau, Anaël, Franker, Mariella A, Hofenk, Jasper, Rodrigues, Ricardo J Cordeiro, Kapitein, Lukas C, Akhmanova, Anna, Jaarsma, Dick, Hoogenraad, Casper C, Sub Cell Biology, Celbiologie
Publikováno v:
Neuron, 89(3), 461-471. Cell Press
Neuron, 89(3), 461-71. Cell Press
Neuron, 89(3), 461. Cell Press
Neuron, 89(3), 461-71. Cell Press
Neuron, 89(3), 461. Cell Press
The development and homeostasis of neurons relies heavily on the selective targeting of vesicles into axon and dendrites. Microtubule-based motor proteins play an important role in polarized transport; however, the sorting mechanism to exclude dendri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f9ebd19eb9dfb96762ba6920df299f
https://doi.org/10.1016/j.neuron.2016.01.022
https://doi.org/10.1016/j.neuron.2016.01.022
Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly
Autor:
Patrícia A. Simões, Reto Gassmann, Cátia de Carvalho, Rita M. Reis, Daniel José Barbosa, Ricardo Celestino, Dhanya K. Cheerambathur, Helena R. Pires, Cláudia Pereira, José B. Gama, Ana Carvalho, João Amorim
Publikováno v:
Gama, J B, Pereira, C, Simões, P A, Celestino, R, Reis, R M, Barbosa, D J, Pires, H R, Carvalho, C, Amorim, J, Carvalho, A X, Cheerambathur, D K & Gassmann, R 2017, ' Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly ', Journal of Cell Biology, vol. 216, no. 4, pp. 943-960 . https://doi.org/10.1083/jcb.201610108
The Journal of Cell Biology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The Journal of Cell Biology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The dynein motor is recruited to the kinetochore to capture spindle microtubules and control the spindle assembly checkpoint. Gama et al. reveal the molecular mechanism of how the Rod–Zw10–Zwilch complex and Spindly mediate dynein recruitment in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4dd69b6f9537932d3a7a0ac63af051
https://hdl.handle.net/20.500.11820/cfdc5439-c4c9-435e-8386-09e192882255
https://hdl.handle.net/20.500.11820/cfdc5439-c4c9-435e-8386-09e192882255
Autor:
Sabine Wohlgemuth, Stefano Maffini, Herbert Waldmann, Michael Saur, Shyamal Mosalaganti, Jenny Keller, Pascaline Rombaut, Tanja Bange, Franz Herzog, Anika Altenfeld, Franziska Müller, Michael Winzker, Annemarie Wehenkel, Andrea Musacchio, Stefan Raunser, Arsen Petrovic
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2017, 216 (4), pp.961-981. ⟨10.1083/jcb.201611060⟩
Journal of Cell Biology, 2017, 216 (4), pp.961-981. ⟨10.1083/jcb.201611060⟩
The Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2017, 216 (4), pp.961-981. ⟨10.1083/jcb.201611060⟩
Journal of Cell Biology, 2017, 216 (4), pp.961-981. ⟨10.1083/jcb.201611060⟩
The Journal of Cell Biology
The Rod–Zw10–Zwilch (RZZ) complex assembles as a fibrous corona on kinetochores before microtubule attachment during mitotic spindle formation. Mosalaganti et al. provide new structural insight into the Spindly–RZZ complex that suggests that it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53480f497020a30a3a577355a03e69d8
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85021848684
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85021848684
Autor:
Paula Nunes, Richard Bouley, Anne Charollais, Dennis Brown, Paolo Meda, Udo Hasler, Thomas Ernandez, Eric Féraille, Isabelle Roth, Michelangelo Foti, Pierluigi Ramadori, Xiaomu Qiao, D. Strebel
Publikováno v:
Autophagy
Autophagy; Vol 9
Autophagy, Vol. 9, No 4 (2013) pp. 550-67
Autophagy; Vol 9
Autophagy, Vol. 9, No 4 (2013) pp. 550-67
Osmotic homeostasis is fundamental for most cells, which face recurrent alterations of environmental osmolality that challenge cell viability. Protein damage is a consequence of hypertonic stress, but whether autophagy contributes to the osmoprotecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77211d1e20f0b953e35c95394263ef9c
https://www.landesbioscience.com/journals/autophagy/article/23662/?nocache=216420114
https://www.landesbioscience.com/journals/autophagy/article/23662/?nocache=216420114
Publikováno v:
Cell Death and Differentiation, Vol. 17, No 11 (2010) pp. 1785-1794
Cell death and differentiation
Cell death and differentiation
During apoptosis, mitochondria lose their membrane potential and undergo fragmentation around the time of release of cytochrome c. Apoptotic fission is at least in part sustained by the translocation of dynamin-related protein 1 (Drp1), normally loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a072b6d880d9593c4706c2219f9e606
https://doi.org/10.1038/cdd.2010.61
https://doi.org/10.1038/cdd.2010.61
Publikováno v:
Brownlow, N, Pike, T, Zicha, D, Collinson, L & Parker, P J 2014, ' Mitotic catenation is monitored and resolved by a PKCε-regulated pathway ', Nature Communications, vol. 5, no. 1, 5685 . https://doi.org/10.1038/ncomms6685
Nature Communications
Nature Communications
Exit from mitosis is controlled by silencing of the spindle assembly checkpoint (SAC). It is important that preceding exit, all sister chromatid pairs are correctly bioriented, and that residual catenation is resolved, permitting complete sister chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0afb78e3db3dccb4ad2abd7b4fcc9b7
https://doi.org/10.1038/ncomms6685
https://doi.org/10.1038/ncomms6685