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Autor:
Andrzej W. Lipkowski, Dymitr Kazem-Bek, Andrzej Temeriusz, Ignacy Zajaczkowski, Janusz Stepinski, S. William Tam
Publikováno v:
International Journal of Peptide and Protein Research. 38:588-592
The bivalent ligand approach, which assumes that two pharmacophores are connected by a spacer, was used to design receptor type-selective ligands for opioid receptors. The first two opioid peptide bivalent ligands with different spacer lengths contai