Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dylan Xavier"'
Autor:
Rebecca C. Poulos, Peter G. Hains, Rohan Shah, Natasha Lucas, Dylan Xavier, Srikanth S. Manda, Asim Anees, Jennifer M. S. Koh, Sadia Mahboob, Max Wittman, Steven G. Williams, Erin K. Sykes, Michael Hecker, Michael Dausmann, Merridee A. Wouters, Keith Ashman, Jean Yang, Peter J. Wild, Anna deFazio, Rosemary L. Balleine, Brett Tully, Ruedi Aebersold, Terence P. Speed, Yansheng Liu, Roger R. Reddel, Phillip J. Robinson, Qing Zhong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Clinical proteomics critically depends on the ability to acquire highly reproducible data over an extended period of time. Here, the authors assess reproducibility over four months across different mass spectrometers and develop a computational appro
Externí odkaz:
https://doaj.org/article/f31d48fe5cbd4e4fb32261099a109959
Autor:
Emanuel Gonçalves, Rebecca C Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J Seneviratne, Erin Sykes, Frances Thomas, Sara Valentini, Steven G Williams, Yangxiu Wu, Dylan Xavier, Karen L MacKenzie, Peter G Hains, Brett Tully, Phillip J Robinson, Qing Zhong, Mathew J Garnett, Roger R Reddel
SummaryThe proteome provides unique insights into biology and disease beyond the genome and transcriptome. Lack of large proteomic datasets has restricted identification of new cancer biomarkers. Here, proteomes of 949 cancer cell lines across 28 tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ab6090375c95783a1345c281a33a98b
https://doi.org/10.1101/2022.02.26.482008
https://doi.org/10.1101/2022.02.26.482008
Autor:
Emanuel Gonçalves, Rebecca C. Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yangxiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip J. Robinson, Qing Zhong, Mathew J. Garnett, Roger R. Reddel
Publikováno v:
Cancer Cell
The proteome provides unique insights into disease biology beyond the genome and transcriptome. A lack of large proteomic datasets has restricted the identification of new cancer biomarkers. Here, proteomes of 949 cancer cell lines across 28 tissue t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3a20c7e98090d73382989efa0e217c
https://pubmed.ncbi.nlm.nih.gov/35839778
https://pubmed.ncbi.nlm.nih.gov/35839778
Autor:
Keith Ashman, Asim Anees, Terence P. Speed, Erin K. Sykes, Roger R. Reddel, Yansheng Liu, Jennifer M. S. Koh, Jean Yang, Merridee A. Wouters, Steven G. Williams, Peter J. Wild, Anna deFazio, Natasha Lucas, Max Wittman, Dylan Xavier, Michael Hecker, Sadia Mahboob, Michael Dausmann, Ruedi Aebersold, Peter G. Hains, Brett Tully, Rohan Shah, Phillip J. Robinson, Qing Zhong, Rosemary L. Balleine, Srikanth S. Manda, Rebecca C. Poulos
Publikováno v:
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop computational methods for improving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72057dd71a63badf92c2a0858853f64
https://hdl.handle.net/20.500.11850/430457
https://hdl.handle.net/20.500.11850/430457
Autor:
Dylan Xavier, Thiri Zaw, Dana Pascovici, Stephen Clarke, Mark P. Molloy, Xiaomin Song, Jemma X. Wu, Ardeshir Amirkhani
Publikováno v:
PROTEOMICS. 16:2118-2127
A standardized procedure for label-free nano-LC-SRM analysis of 32 high-medium abundance proteins from nondepleted human plasma was established and SRM data were acquired on 45 separate days for a control sample that was independently prepared on 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b882e920e5e5d2c33b5e85027a1d95c4
https://doi.org/10.1002/pmic.201500507
https://doi.org/10.1002/pmic.201500507
Autor:
Dylan Xavier, Sadia Mahboob, Jing Xue, Peter G. Hains, Natasha Lucas, Maiken Lise Marcker Espersen, Anna deFazio, Andrew B Robinson, Rosemary L. Balleine, Phillip J. Robinson
Publikováno v:
Journal of Proteome Research.
We have developed a streamlined proteomic sample preparation protocol termed Accelerated Barocycler Lysis and Extraction (ABLE) that substantially reduces the time and cost of tissue sample processing. ABLE is based on pressure cycling technology (PC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5b81867c72ea60ad02603b903bd76e
https://doi.org/10.1021/acs.jproteome.8b00684
https://doi.org/10.1021/acs.jproteome.8b00684
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 83:1878-1886
Low molecular weight peptides derived from the breakdown of crystallins have been reported in adult human lenses. The proliferation of these LMW peptides coincides with the earliest stages of cataract formation, suggesting that the protein cleavages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52bf286984f7c5eb24c45657b127d29a
https://doi.org/10.1002/prot.24872
https://doi.org/10.1002/prot.24872
Autor:
Dylan Xavier, Jonathan Cebon, Mark P. Molloy, Laura J Vella, Jimmy Parker, Robert Parker, Ardeshir Amirkhani
Publikováno v:
Frontiers in Oncology, Vol 5 (2015)
Frontiers in Oncology
Frontiers in Oncology
The treatment of melanoma by targeted inhibition of the mutated kinase BRAF with small molecules only temporarily suppresses metastatic disease. In the face of chemical inhibition tumor plasticity, both innate and adaptive, promotes survival through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae96e3d84688867ecf9490fff72407e5
Autor:
Xiaomin Song, Michael G. Friedrich, Jason D. McArthur, Brian Lyons, Roger J.W. Truscott, Dylan Xavier, Shih-Ping Su, John A. Aquilina
Publikováno v:
Aging Cell. 11:1125-1127
Summary The centre of the human lens, which is composed of proteins that were synthesized prior to birth, is an ideal model for the evaluation of long-term protein stability and processes responsible for the degradation of macromolecules. By analysin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e3faf5f1762bb89e72622dde73c5e1
https://doi.org/10.1111/j.1474-9726.2012.00860.x
https://doi.org/10.1111/j.1474-9726.2012.00860.x
Autor:
Dylan Xavier, Raffaella Bianucci, Do Seon Lim, Dong Hoon Shin, Prathiba Ravishankar, Mehdi Mirzaei, Paul A. Haynes, Jana Jones
Publikováno v:
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 374:20150373
We performed proteomics analysis on four skin and one muscle tissue samples taken from three ancient Egyptian mummies of the first intermediate period, approximately 4200 years old. The mummies were first dated by radiocarbon dating of the accompany-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234f2b7e64531cccc1e0b27eea1e6cf8
https://doi.org/10.1098/rsta.2015.0373
https://doi.org/10.1098/rsta.2015.0373