Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dylan V Neel"'
Autor:
Dylan V. Neel, Clement Ma, Natalie B. Collins, Jason L. Hornick, George D. Demetri, David S. Shulman
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 170-178 (2023)
Abstract Background Synovial sarcoma (SS) accounts for 8%–10% of all soft‐tissue sarcomas. Clinical presentation and outcomes vary, yet discrete risk groups based on validated prognostic indices are not defined for the full spectrum of patients w
Externí odkaz:
https://doaj.org/article/da807d720bf34f49befe2d047ca5dbb0
Publikováno v:
Cancer Medicine, Vol 9, Iss 13, Pp 4495-4500 (2020)
Abstract Background The sponsorship mix of trials relevant to young people with cancer has not been reported. Understanding this sponsorship mix may have implications for policies and regulations related to pediatric cancer drug development. Methods
Externí odkaz:
https://doaj.org/article/dd0ae4519f4d4584bb13b3dced57cd6f
Autor:
Nicole J. Yang, Dylan V. Neel, Liwen Deng, Michelle Heyang, Angela Kennedy-Curran, Victoria S. Tong, Jin Mo Park, Isaac M. Chiu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Bacterial products are able to act on nociceptive neurons during pathogenic infection. Neurogenic inflammation is an active part of pain signaling and has recently been shown to impact host-pathogen defense. Bacillus anthracis Edema Toxin (ET) produc
Externí odkaz:
https://doaj.org/article/e240264f8dfc435faf6001284ed28aaf
Autor:
Felipe A. Pinho-Ribeiro, Liwen Deng, Dylan V. Neel, Ozge Erdogan, Himanish Basu, Daping Yang, Samantha Choi, Alec J. Walker, Simone Carneiro-Nascimento, Kathleen He, Glendon Wu, Beth Stevens, Kelly S. Doran, Dan Levy, Isaac M. Chiu
Publikováno v:
Nature. 615:472-481
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::192ec57142763295acf6ef7ad5af0596
https://doi.org/10.1038/s41586-023-05753-x
https://doi.org/10.1038/s41586-023-05753-x
Autor:
Dylan V. Neel, Clement Ma, Natalie B. Collins, Jason L. Hornick, George D. Demetri, David S. Shulman
Publikováno v:
Cancer Medicine. 12:170-178
Synovial sarcoma (SS) accounts for 8%-10% of all soft-tissue sarcomas. Clinical presentation and outcomes vary, yet discrete risk groups based on validated prognostic indices are not defined for the full spectrum of patients with SS.We performed a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208b4a48b382091b028e9e5932693a8e
https://doi.org/10.1002/cam4.4909
https://doi.org/10.1002/cam4.4909
Publikováno v:
Immunological Reviews. 311:130-150
In the central nervous system (CNS), execution of programmed cell death (PCD) is crucial for proper neurodevelopment. However, aberrant activation of these pathways in adult CNS leads to neurodegenerative diseases including amyotrophic lateral sclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9904389763db317d9bd08224227cbd0a
https://doi.org/10.1111/imr.13083
https://doi.org/10.1111/imr.13083
Autor:
Dylan V Neel, Himanish Basu, Georgia Gunner, Matthew D Bergstresser, Richard M. Giadone, Haeji Chung, Rui Miao, Vicky Chou, Eliza M. Brody, Xin Jiang, Edward B. Lee, Christine Marques, Aaron Held, Brian Wainger, Clotilde Lagier-Tourenne, Yong-Jie Zhang, Leonard Petrucelli, Tracy L. Young-Pearse, Alice S Chen-Plotkin, Lee L. Rubin, Judy Lieberman, Isaac M Chiu
SummaryMitochondrial dysfunction and axon loss are hallmarks of neurologic diseases. Gasdermin (GSDM) proteins are executioner pore-forming molecules that mediate cell death, yet their roles in the central nervous system (CNS) are not well understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bea31c31776a3ce2a086b6cc022faa8
https://doi.org/10.1101/2022.11.01.513927
https://doi.org/10.1101/2022.11.01.513927
Autor:
Dylan V. Neel, Himanish Basu, Georgia Gunner, Matthew D. Bergstresser, Richard M. Giadone, Haeji Chung, Rui Miao, Vicky Chou, Eliza Brody, Xin Jiang, Edward Lee, Michelle E. Watts, Christine Marques, Aaron Held, Brian Wainger, Clotilde Lagier-Tourenne, Yong-Jie Zhang, Leonard Petrucelli, Tracy L. Young-Pearse, Alice S. Chen-Plotkin, Lee L. Rubin, Judy Lieberman, Isaac M. Chiu
Publikováno v:
Neuron. 111:1222-1240.e9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eebeb12852883915eae6742b8988c12
https://doi.org/10.1016/j.neuron.2023.02.019
https://doi.org/10.1016/j.neuron.2023.02.019
Autor:
Nicole J. Yang, Jörg Isensee, Dylan V. Neel, Andreza U. Quadros, Han-Xiong Bear Zhang, Justas Lauzadis, Sai Man Liu, Stephanie Shiers, Andreea Belu, Shilpa Palan, Sandra Marlin, Jacquie Maignel, Angela Kennedy-Curran, Victoria S. Tong, Mahtab Moayeri, Pascal Röderer, Anja Nitzsche, Mike Lu, Bradley L. Pentelute, Oliver Brüstle, Vineeta Tripathi, Keith A. Foster, Theodore J. Price, R. John Collier, Stephen H. Leppla, Michelino Puopolo, Bruce P. Bean, Thiago M. Cunha, Tim Hucho, Isaac M. Chiu
Publikováno v:
Nat Neurosci
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Bacterial products can act on neurons to alter signaling and function. Here, we find that dorsal root ganglia (DRG) sensory neurons are enriched for ANTXR2, the high-affinity receptor for anthrax toxins. Anthrax toxins are composed of protective anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51535d2a537fb4d96983bf570b33773
https://europepmc.org/articles/PMC9388775/
https://europepmc.org/articles/PMC9388775/
Autor:
Clement Ma, David S. Shulman, Dylan V. Neel, Jaclynne H Nader, Florence T. Bourgeois, Steven G. DuBois
Publikováno v:
Pediatr Blood Cancer
OBJECTIVES: Understanding trends in characteristics of early phase trials that allow minors with cancer to participate may inform additional efforts to improve cancer drug development for young people. METHODS: We accessed data for oncology phase 1 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83a3938ab8c064cfe32e9a08b510701
https://doi.org/10.1002/pbc.28694
https://doi.org/10.1002/pbc.28694