Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dylan S. Zuckerman"'
Autor:
Dylan S. Zuckerman, K. A. Woerpel
Publikováno v:
Org Lett
Using a chiral (-)-menthone auxiliary, enantiopure cyclic derivatives of Baylis-Hillman adducts were synthesized. A diastereoselective peroxidation reaction was used to introduce an oxygen atom and establish another stereocenter. The resulting produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d60f16792c24700bf7af156ad68b2c8
https://doi.org/10.1021/acs.orglett.0c03439
https://doi.org/10.1021/acs.orglett.0c03439
Autor:
Dylan S. Zuckerman, K. A. Woerpel
Publikováno v:
Tetrahedron
Cyclic derivatives of Baylis–Hillman adducts were synthesized. Cobalt-catalyzed peroxidation of these cyclic lactones afforded silyl peroxides in diastereomeric ratios ranging from 91:9 to 97:3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1899f9d0e9959b5db2c078f377a8ee83
https://pubmed.ncbi.nlm.nih.gov/32831414
https://pubmed.ncbi.nlm.nih.gov/32831414
Autor:
Amy Y. Chan, Daniel W. Heindel, Christopher A. Vaiana, Jacob D. Daniels, Michael M. Gaschler, Yulia Y. Tyurina, Andrei V. Bekish, Pieter H. Bos, Lingplak Ye, Vadim V. Shmanai, Brent R. Stockwell, Lara K. Mahal, Eveliz Peguero-Pereira, Mikhail S. Shchepinov, Joleen M. Csuka, Eduard Reznik, Alexander A. Andia, Hengrui Liu, K. A. Woerpel, Valerian E. Kagan, Maksim A. Fomich, Annie J. Lin, Brisa Hurlocker, Dylan S. Zuckerman
Publikováno v:
Nature Chemical Biology. 14:507-515
Ferroptosis is a non-apoptotic form of regulated cell death caused by the failure of the glutathione-dependent lipid-peroxide-scavenging network. FINO2 is an endoperoxide-containing 1,2-dioxolane that can initiate ferroptosis selectively in engineere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e914e034d88a84e16836e37cf89228ed
https://doi.org/10.1038/s41589-018-0031-6
https://doi.org/10.1038/s41589-018-0031-6