Výsledky vyhledávání - "Dylan R Edwards"

Akademický článek

TGF-β-elicited induction of tissue inhibitor of metalloproteinases (TIMP)-3 expression in fibroblasts involves complex interplay between Smad3, p38α, and ERK1/2.

Autor: Suvi-Katri Leivonen, Konstantinos Lazaridis, Julie Decock, Andrew Chantry, Dylan R Edwards, Veli-Matti Kähäri

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e57474 (2013)

Transforming growth factor-β (TGF-β) promotes extracellular matrix deposition by down-regulating the expression of matrix degrading proteinases and upregulating their inhibitors. Tissue inhibitor of metalloproteinases (TIMP)-3 is an ECM-associated

Externí odkaz: https://doaj.org/article/2d4c950d9b114d0e8632948fbe111271

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Akademický článek

Genome-Wide Responses of Female Fruit Flies Subjected to Divergent Mating Regimes.

Autor: Dave T Gerrard, Claudia Fricke, Dominic A Edward, Dylan R Edwards, Tracey Chapman

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e68136 (2013)

Elevated rates of mating and reproduction cause decreased female survival and lifetime reproductive success across a wide range of taxa from flies to humans. These costs are fundamentally important to the evolution of life histories. Here we investig

Externí odkaz: https://doaj.org/article/72fd15ad28434f2fbbb2d94daaa5b607

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Akademický článek

Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression.

Autor: Boye S Nielsen, Mikala Egeblad, Fritz Rank, Hanne A Askautrud, Caroline J Pennington, Tanja X Pedersen, Ib J Christensen, Dylan R Edwards, Zena Werb, Leif R Lund

Publikováno v: PLoS ONE, Vol 3, Iss 8, p e2959 (2008)

Matrix metalloproteinase (MMP) 13 (collagenase 3) is an extracellular matrix remodeling enzyme that is induced in myofibroblasts during the earliest invasive stages of human breast carcinoma, suggesting that it is involved in tumor progression. Durin

Externí odkaz: https://doaj.org/article/deea948b4a904eca8264f2f02979894f

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