Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dylan J, Harney"'
Autor:
Jun Yup Lee, Dylan J Harney, Jonathan D Teo, John B Kwok, Greg T. Sutherland, Mark Larance, Anthony S Don
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-20 (2023)
Abstract Background The risk for dementia increases exponentially from the seventh decade of life. Identifying and understanding the biochemical changes that sensitize the ageing brain to neurodegeneration will provide new opportunities for dementia
Externí odkaz:
https://doaj.org/article/ec7ffc28bc054f9fa80acef9dc34dab3
Autor:
Jun Yup Lee, Dylan J. Harney, Jonathan D. Teo, John B. Kwok, Greg T. Sutherland, Mark Larance, Anthony S. Don
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f63074ce0a434945aecfe0f702fa9d07
Autor:
Luke Hatchwell, Dylan J. Harney, Michelle Cielesh, Kieren Young, Yen Chin Koay, John F. O’Sullivan, Mark Larance
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3566-3582.e4 (2020)
Summary: Every-other-day fasting (EODF) is an effective intervention for the treatment of metabolic disease, including improvements in liver health. But how the liver proteome is reprogrammed by EODF is currently unknown. Here, we use EODF in mice an
Externí odkaz:
https://doaj.org/article/237e432c2e57473e973503e386901c72
Autor:
Andries Van Woerkom, Dylan J Harney, Shilpa R. Nagarajan, Mariam F. Hakeem-Sanni, Jinfeng Lin, Matthew Hooke, Tamara Pulpitel, Gregory J Cooney, Mark Larance, Darren N. Saunders, Amanda E Brandon, Andrew J. Hoy
Fatty liver is characterised by the expansion of lipid droplets and is associated with the development of many metabolic diseases, including insulin resistance, dyslipidaemia and cardiovascular disease. We assessed the morphology of hepatic lipid dro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4adca0bd40358372d7dcaf7c4862c99b
https://doi.org/10.1101/2023.03.09.531813
https://doi.org/10.1101/2023.03.09.531813
Autor:
Rachel M. Woodhouse, Gabriele Buchmann, Matthew Hoe, Dylan J. Harney, Jason K.K. Low, Mark Larance, Peter R. Boag, Alyson Ashe
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2259-2272.e5 (2018)
Summary: Some epigenetic modifications are inherited from one generation to the next, providing a potential mechanism for the inheritance of environmentally acquired traits. Transgenerational inheritance of RNAi phenotypes in Caenorhabditis elegans p
Externí odkaz:
https://doaj.org/article/594e20c36bba4b86952e67560aa101f9
Autor:
Harunori Yoshikawa, Mark Larance, Dylan J Harney, Ramasubramanian Sundaramoorthy, Tony Ly, Tom Owen-Hughes, Angus I Lamond
Publikováno v:
eLife, Vol 7 (2018)
We describe Ribo Mega-SEC, a powerful approach for the separation and biochemical analysis of mammalian polysomes and ribosomal subunits using Size Exclusion Chromatography and uHPLC. Using extracts from either cells, or tissues, polysomes can be sep
Externí odkaz:
https://doaj.org/article/1e11ef7eff2e48e0936f253c44f03464
Autor:
Dylan J. Harney, Michelle Cielesh, Georgia E. Roberts, Isabelle K. Vila, Barney Viengkhou, Markus J. Hofer, Nadine Laguette, Mark Larance
Publikováno v:
Cell Reports. 42:112559
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1082103743a35b045dbf3f12b4e7ccc3
https://doi.org/10.1016/j.celrep.2023.112559
https://doi.org/10.1016/j.celrep.2023.112559
Autor:
Sarah J. Mitchell, Abhishek Singh, John F. O'Sullivan, Victoria C. Cogger, Dylan J. Harney, Nathan L. Price, Eun Young Kim, Yen Chin Koay, Devin Wahl, David G. LeCouteur, Miguel A. Aon, Mark Larance, Tamara Pulpitel, Vince Guiterrez, Ahmed Ali, Antonio Diaz, Ana Maria Cuervo, Rafael de Cabo, Carlos Fernández-Hernando, Michel Bernier, John Mach
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 6, Iss 1, Pp 1-11 (2020)
NPJ Aging and Mechanisms of Disease
NPJ Aging and Mechanisms of Disease
There is an unmet need and urgency to find safe and effective anti-obesity interventions. Our recent study in mice fed on obesogenic diet found that treatment with the alcohol aversive drug disulfiram reduced feeding efficiency and led to a decrease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ae85545bbde050fbcf2e6a8c36bfb6
https://doaj.org/article/6764f6e5a0bd403f9dbc67a86fdcd3e6
https://doaj.org/article/6764f6e5a0bd403f9dbc67a86fdcd3e6
Autor:
Dylan J. Harney, Mark Larance
Publikováno v:
Journal of proteome research. 21(4)
Liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis of secreted proteins has contributed to our understanding of human disease and physiology but is limited by its need for accurate protein database annotation. Common assumptions used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80e76ddd1417a0fc6bdf604c5a0318e
https://pubmed.ncbi.nlm.nih.gov/35156369
https://pubmed.ncbi.nlm.nih.gov/35156369
Autor:
Mark Larance, Zhiduan Su, Luke Hatchwell, Amy T. Hutchison, Leonie K. Heilbronn, David E. James, Samantha L. Hocking, Dylan J. Harney
Publikováno v:
Mol Cell Proteomics
Unbiased and sensitive quantification of low abundance small proteins in human plasma (e.g. hormones, immune factors, metabolic regulators) remains an unmet need. These small protein factors are typically analyzed individually and using antibodies th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d634d5c3a3304bc2d366fe4daddd10
https://doi.org/10.1074/mcp.tir119.001562
https://doi.org/10.1074/mcp.tir119.001562