Methyl-CpG-binding domain 9 (MBD9) is required for H2A.Z incorporation into chromatin at a subset of H2A.Z-enriched regions in the Arabidopsis genome.

Autor: Paja Sijacic, Dylan H Holder, Marko Bajic, Roger B Deal

Publikováno v: PLoS Genetics, Vol 15, Iss 8, p e1008326 (2019)

The SWR1 chromatin remodeling complex, which deposits the histone variant H2A.Z into nucleosomes, has been well characterized in yeast and animals, but its composition in plants has remained uncertain. We used the conserved SWR1 subunit ACTIN RELATED

Externí odkaz: https://doaj.org/article/255c9e96b019450c9d3c48dbacbff7df

Macro-to-micro interfacing to microfluidic channels using 3D-printed templates: application to time-resolved secretion sampling of endocrine tissue

Autor: Katarena I. Ford, Jessica C. Brooks, Mark D. Holtan, Dylan H. Holder, Christopher J. Easley

Publikováno v: The Analyst. 141:5714-5721

Employing 3D-printed templates for macro-to-micro interfacing, a passively operated polydimethysiloxane (PDMS) microfluidic device was designed for time-resolved secretion sampling from primary murine islets and epidiymal white adipose tissue explant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb4bba744c23fd3594fb5c94c5d8acc
https://doi.org/10.1039/c6an01055e

Aberrant Inclusion of a Poison Exon Causes Dravet Syndrome and Related SCN1A-Associated Genetic Epilepsies

Autor: Gemma L. Carvill, Krysta L. Engel, Aishwarya Ramamurthy, J. Nicholas Cochran, Jolien Roovers, Hannah Stamberger, Nicholas Lim, Amy L. Schneider, Georgie Hollingsworth, Dylan H. Holder, Brigid M. Regan, James Lawlor, Lieven Lagae, Berten Ceulemans, E. Martina Bebin, John Nguyen, Gregory S. Barsh, Sarah Weckhuysen, Miriam Meisler, Samuel F. Berkovic, Peter De Jonghe, Ingrid E. Scheffer, Richard M. Myers, Gregory M. Cooper, Heather C. Mefford, Pasquale Striano, Federico Zara, Ingo Helbig, Rikke S. Møller, Sarah von Spiczak, Hiltrud Muhle, Hande Caglayan, Katalin Sterbova, Dana Craiu, Dorota Hoffman, Anna-Elina Lehesjoki, Kaja Selmer, Christel Depienne, Johannes Lemke, Carla Marini, Renzo Guerrini, Bernd Neubauer, Tiina Talvik, Eric Leguern, Peter de Jonghe

Publikováno v: Møller, R S & EuroEPINOMICS Rare Epilepsy Syndrome, Myoclonic-Astatic Epilepsy, and Dravet Working Group 2018, ' Aberrant Inclusion of a Poison Exon Causes Dravet Syndrome and Related SCN1A-Associated Genetic Epilepsies ', American Journal of Human Genetics, vol. 103, no. 6, pp. 1022-1029 . https://doi.org/10.1016/j.ajhg.2018.10.023
The American journal of human genetics

Developmental and epileptic encephalopathies (DEEs) are a group of severe epilepsies characterized by refractory seizures and developmental impairment. Sequencing approaches have identified causal genetic variants in only about 50% of individuals wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea831a5b15156ae4f875e499f7848fc
https://pubmed.ncbi.nlm.nih.gov/30526861