Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dylan G. Wynne"'
Autor:
Michael Koa-Wing, Anthony W.C. Chow, Graeme J. Kirkwood, M Leo, David Hildick-Smith, John P. Foran, Christopher B. Pepper, David J. Fox, Sandeep Panikker, Timothy R. Betts, Derick Todd, Oliver Ormerod, Oliver R. Segal, Tom Wong, D W Davies, Dylan G. Wynne, Prapa Kanagaratnam, Sandra Cabrera Gomez
Publikováno v:
Catheterization and Cardiovascular Interventions. 89:484-492
Objectives This study aimed at assessing the feasibility and long-term efficacy of left atrial appendage occlusion (LAAO) in a “real world” setting. Background Although LAAO has recently emerged as an alternative to oral anticoagulants in patient
Autor:
Timothy R, Betts, Milena, Leo, Sandeep, Panikker, Prapa, Kanagaratnam, Michael, Koa-Wing, David Wyn, Davies, David, Hildick-Smith, Dylan G, Wynne, Oliver, Ormerod, Oliver R, Segal, Anthony W, Chow, Derick, Todd, Sandra, Cabrera Gomez, Graeme J, Kirkwood, David, Fox, Chris, Pepper, John, Foran, Tom, Wong
Publikováno v:
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions. 89(3)
This study aimed at assessing the feasibility and long-term efficacy of left atrial appendage occlusion (LAAO) in a "real world" setting.Although LAAO has recently emerged as an alternative to oral anticoagulants in patients with atrial fibrillation
Publikováno v:
Heart, lungcirculation. 23(11)
Background With the increased application of structural heart intervention techniques, there is concern over increasing radiation dose, especially during lengthy procedures. Methods We compared data from 91 consecutive single-vessel percutaneous coro
Publikováno v:
European Heart Journal. 16:74-81
Acute myocardial ischemia and subsequent reperfusion result in biochemical and ionic changes in cardiac myocytes which cause contracture of the muscle and a reduced contractile force. Whether changes observed in single myocytes isolated from ischaemi
Autor:
Federica del Monte, Dylan G. Wynne, Nicola Ferrara, Lesley A Brown, Peter O'Gara, Sian E. Harding, Philip A. Poole-Wilson
Publikováno v:
Scopus-Elsevier
We have characterized the age-related changes of contractility and beta-adrenoceptor function in isolated cardiac myocytes from guinea-pigs. We used either adult animals from 2 to 14 weeks of age, where body weight increases linearly with age, or sen
Autor:
F. Del Monte, Sian E. Harding, Dylan G. Wynne, John Pepper, Philip A. Poole-Wilson, A J Kaumann
Publikováno v:
Circulation. 88:854-863
BACKGROUND Both beta 1- and beta 2-adrenoceptors (beta 1 AR and beta 2 AR) are present in human ventricle. This study was designed to determine whether the two subtypes contribute to contraction in single myocytes from human heart. METHODS AND RESULT
Autor:
Louis W. Wang, Emily Granger, David W. Baron, Rajesh N. Subbiah, Dylan G. Wynne, Eugene Kotlyar
Publikováno v:
Circulation. 126:2018-2019
A 32-year-old man underwent routine elective left heart catheterization 1 year after orthotopic cardiac transplantation for advanced congestive cardiac failure secondary to familial dilated cardiomyopathy. At the time of transplantation, the donor he
Publikováno v:
European journal of pharmacology. 310(2-3)
Chronic activation of the sympathetic nervous system in human heart failure is believed to cause cardiac beta-adrenoceptor desensitisation. We have investigated the relationship between beta-adrenoceptor desensitisation and cyclic AMP levels in cardi
Publikováno v:
Molecular and Cellular Biochemistry. 157
Transitions in sarcomeric alpha-actin and cardiac myosin heavy chain (MHC) gene expression have been useful as molecular markers for the development of cardiac hypertrophy and failure. In simpler model systems, alpha-actin expression has been useful
Autor:
G. Vescovo, F. Del Monte, C. H. Davies, Sian E. Harding, Peter O'Gara, Dylan G. Wynne, Lesley A Brown, Philip A. Poole-Wilson
Publikováno v:
Basic research in cardiology. 91
Myocytes from failing human ventricle contract and relax more slowly than those from non-failing. This has been suggested to result from the lowering of basal cyclic AMP level in failing myocardium, and the consequent withdrawal of a tonic lusitropic