Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dylan G. Chitwood"'
Autor:
Dylan G. Chitwood, Qinghua Wang, Stephanie R. Klaubert, Kiana Green, Cathy H. Wu, Sarah W. Harcum, Christopher A. Saski
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Chinese hamster ovary (CHO) cell lines are widely used to manufacture biopharmaceuticals. However, CHO cells are not an optimal expression host due to the intrinsic plasticity of the CHO genome. Genome plasticity can lead to chromosomal rear
Externí odkaz:
https://doaj.org/article/b7bcaffad73e48c990a4f49fc0105040
Autor:
Dylan G. Chitwood, Qinghua Wang, Kathryn Elliott, Aiyana Bullock, Dwon Jordana, Zhigang Li, Cathy Wu, Sarah W. Harcum, Christopher A. Saski
Publikováno v:
BMC Biotechnology, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background As bioprocess intensification has increased over the last 30 years, yields from mammalian cell processes have increased from 10’s of milligrams to over 10’s of grams per liter. Most of these gains in productivity can be attrib
Externí odkaz:
https://doaj.org/article/0028912c2305477aa65494d16f1770fc
Autor:
Lauren T. Cordova, Hussain Dahodwala, Kathryn S. Elliott, Jongyoun Baik, Daniel C. Odenewelder, Douglas Nmagu, Bradley A. Skelton, Lisa Uy, Stephanie R. Klaubert, Benjamin F. Synoground, Dylan G. Chitwood, Venkata Gayatri Dhara, Harnish Mukesh Naik, Caitlin S. Morris, Seongkyu Yoon, Michael Betenbaugh, Jon Coffman, Frank Swartzwelder, Michael P. Gillmeister, Sarah W. Harcum, Kelvin H. Lee
Publikováno v:
Biotechnology and bioengineeringREFERENCES.
Due to the favorable attributes of Chinese hamster ovary (CHO) cells for therapeutic proteins and antibodies biomanufacturing, companies generate proprietary cells with desirable phenotypes. One key attribute is the ability to stably express multi-gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b57544b52ac58fe499c41499dcc9c0
https://pubmed.ncbi.nlm.nih.gov/36411514
https://pubmed.ncbi.nlm.nih.gov/36411514
Autor:
Stephanie R, Klaubert, Dylan G, Chitwood, Hussain, Dahodwala, Madison, Williamson, Rachel, Kasper, Kelvin H, Lee, Sarah W, Harcum
Publikováno v:
Methods in enzymology. 660
Chinese hamster ovary (CHO) cell cultures in industry are most commonly conducted as fed-batch cultures in computer-controlled bioreactors, though most preliminary studies are conducted in fed-batch shake flasks. To improve comparability between bior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2c894c728113585946cb422b940bf8b
https://pubmed.ncbi.nlm.nih.gov/34742394
https://pubmed.ncbi.nlm.nih.gov/34742394
Autor:
Stephanie R. Klaubert, Rachel Kasper, Hussain Dahodwala, Kelvin H. Lee, Dylan G. Chitwood, Madison Williamson, Sarah W. Harcum
Publikováno v:
Methods in Enzymology ISBN: 9780323907378
Chinese hamster ovary (CHO) cell cultures in industry are most commonly conducted as fed-batch cultures in computer-controlled bioreactors, though most preliminary studies are conducted in fed-batch shake flasks. To improve comparability between bior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26bfb4515120a7f74a6c40944847d2fb
https://doi.org/10.1016/bs.mie.2021.05.005
https://doi.org/10.1016/bs.mie.2021.05.005
Autor:
Christopher A. Saski, Kathryn Elliott, Qing Wang, Jordana D, Dylan G. Chitwood, Sarah W. Harcum, Bullock A, Cathy H. Wu, Zhen Li
As bioprocess intensification has increased over the last 30 years, yields from mammalian cell processes have increased from 10’s of milligrams to over 10’s of grams per liter. Most of these gains in productivity have been due to increasing cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0481c432c4081d2ccb2ef885cf942e5d
https://doi.org/10.1101/823252
https://doi.org/10.1101/823252