Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Dylan Conklin"'
Autor:
Neil A. O’Brien, Martina S. J. McDermott, Dylan Conklin, Tong Luo, Raul Ayala, Suruchi Salgar, Kevin Chau, Emmanuelle DiTomaso, Naveen Babbar, Faye Su, Alex Gaither, Sara A. Hurvitz, Ronald Linnartz, Kristine Rose, Samit Hirawat, Dennis J. Slamon
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-17 (2020)
Abstract Background Combined targeting of CDK4/6 and ER is now the standard of care for patients with advanced ER+/HER2− breast cancer. However, acquired resistance to these therapies frequently leads to disease progression. As such, it is critical
Externí odkaz:
https://doaj.org/article/2ebab795d742494f80b2463e971ee39c
Autor:
Richard S. Finn, Dennis J. Slamon, James G. Christensen, Ian Taylor, Carolyn D. Britten, David J. Cohen, Lee Anderson, Charles Ginther, Neil A. O'Brien, Amrita J. Desai, Dylan Conklin, Ondrej Kalous
PDF file, 58K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5383d7d0d8fa2cde7322cfafdf3f0a78
https://doi.org/10.1158/1535-7163.22499194.v1
https://doi.org/10.1158/1535-7163.22499194.v1
Autor:
Dennis J. Slamon, Colleen Mockbee, Sara Hurvitz, Erika von Euw, Ondrej Kalous, Christophe Marchal, Ann Mc Nulty, Josh Thomas, Kevin Chau, Tong Luo, Richard Beckmann, Dylan Conklin, Neil O'Brien
Whole exome sequencing analysis of a panel of 44 breast cancer cell lines, enriched for somatic alterations with functional consequence in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ceaad6a7dbd0936e5285def17f13c8
https://doi.org/10.1158/1535-7163.22510075
https://doi.org/10.1158/1535-7163.22510075
Autor:
Richard S. Finn, Dennis J. Slamon, Mikhail Akimov, Cornelia Quadt, Neil A. O'Brien, Raul Ayala, Dylan Conklin, Ondrej Kalous, Amrita J. Desai, Amy M. Rogers, Adrian Anghel, Zev A. Wainberg
Supplementary Table 1 PDF file - 69K, NVP-AUY922 IC50 concentrations and response to trastuzumab in HER2 amplified breast cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe55e8bff46e84d760c13bddf74be55
https://doi.org/10.1158/1535-7163.22498455.v1
https://doi.org/10.1158/1535-7163.22498455.v1
Autor:
Richard S. Finn, Dennis J. Slamon, James G. Christensen, Ian Taylor, Carolyn D. Britten, David J. Cohen, Lee Anderson, Charles Ginther, Neil A. O'Brien, Amrita J. Desai, Dylan Conklin, Ondrej Kalous
PDF file, 77K, Comparison of the effect of dacomitinib at 48 hrs and 5 days on cell cycle and apoptosis in BT-474 and SK-BR-3 lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e02bc251575b4be1c0ecabdaddb47c
https://doi.org/10.1158/1535-7163.22499206.v1
https://doi.org/10.1158/1535-7163.22499206.v1
Autor:
Richard S. Finn, Dennis J. Slamon, James G. Christensen, Ian Taylor, Carolyn D. Britten, David J. Cohen, Lee Anderson, Charles Ginther, Neil A. O'Brien, Amrita J. Desai, Dylan Conklin, Ondrej Kalous
PDF file, 55K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e6d438b62242e7736f3b63bee22a9c
https://doi.org/10.1158/1535-7163.22499191
https://doi.org/10.1158/1535-7163.22499191
Autor:
Richard S. Finn, Dennis J. Slamon, James G. Christensen, Ian Taylor, Carolyn D. Britten, David J. Cohen, Lee Anderson, Charles Ginther, Neil A. O'Brien, Amrita J. Desai, Dylan Conklin, Ondrej Kalous
PDF file, 60K, Effect of dacomitinib on apoptosis in BT-474 and SK-BR-3 parental lines and lines resistant to trastuzumab and lapatinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ce5222a69f92fff3ef97d1280324b3
https://doi.org/10.1158/1535-7163.22499200
https://doi.org/10.1158/1535-7163.22499200
Autor:
Richard S. Finn, Dennis J. Slamon, James G. Christensen, Ian Taylor, Carolyn D. Britten, David J. Cohen, Lee Anderson, Charles Ginther, Neil A. O'Brien, Amrita J. Desai, Dylan Conklin, Ondrej Kalous
PDF file, 68K, Quantification of proteins from Western blots in Figure 3 by densitometry using ImageJ software.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10766c9cdcef617661e8d4ceeb44f9df
https://doi.org/10.1158/1535-7163.22499188
https://doi.org/10.1158/1535-7163.22499188
Autor:
Richard S. Finn, Dennis J. Slamon, Mikhail Akimov, Cornelia Quadt, Neil A. O'Brien, Raul Ayala, Dylan Conklin, Ondrej Kalous, Amrita J. Desai, Amy M. Rogers, Adrian Anghel, Zev A. Wainberg
Supplementary Legends PDF file - 78K, Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b2370fd2ecb23091018ece93fdf5a7
https://doi.org/10.1158/1535-7163.22498458
https://doi.org/10.1158/1535-7163.22498458
Autor:
Dennis J. Slamon, Colleen Mockbee, Sara Hurvitz, Erika von Euw, Ondrej Kalous, Christophe Marchal, Ann Mc Nulty, Josh Thomas, Kevin Chau, Tong Luo, Richard Beckmann, Dylan Conklin, Neil O'Brien
The cyclinD:CDK4/6:Rb axis is dysregulated in a variety of human cancers. Targeting this pathway has proven to be a successful therapeutic approach in ER+ breast cancer. In this study, in vitro and in vivo preclinical breast cancer models were used t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4d4dd18ca8f68088a433e5cedb39f3
https://doi.org/10.1158/1535-7163.c.6539497.v1
https://doi.org/10.1158/1535-7163.c.6539497.v1