Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Dylan C. Dean"'
Autor:
Pichaya Thanindratarn, Ran Wei, Dylan C. Dean, Arun Singh, Noah Federman, Scott D. Nelson, Francis J. Hornicek, Zhenfeng Duan
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3721-3737 (2021)
T‐lymphokine‐activated killer (T‐LAK) cell‐originated protein kinase (TOPK) is an emerging target with critical roles in various cancers; however, its expression and function in osteosarcoma remain unexplored. We evaluated TOPK expression usi
Externí odkaz:
https://doaj.org/article/dad7f96840d24a35ade73793916c2808
Autor:
Xiaoyang Li, Dylan C. Dean, Al Ferreira, Scott D. Nelson, Francis J. Hornicek, Shengji Yu, Zhenfeng Duan
Publikováno v:
Cancer Control, Vol 28 (2021)
Background The dedifferentiated variant of chondrosarcoma is highly aggressive and carries an especially grim prognosis. While chemotherapeutics has failed to benefit patients with dedifferentiated chondrosarcoma significantly, preclinical chemosensi
Externí odkaz:
https://doaj.org/article/4bc285e7b973464fabe3bc6c3e5e7cc4
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-11 (2019)
Abstract Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the f
Externí odkaz:
https://doaj.org/article/df6e6b541a0f47168e2711a5ef5ea9e0
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 13 (2021)
Externí odkaz:
https://doaj.org/article/001052099b42451789fc477b01b99806
Autor:
Wenlong Feng, Dylan C. Dean, Francis J. Hornicek, Jinglu Wang, Yanyan Jia, Zhenfeng Duan, Huirong Shi
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Although ataxia-telangiectasia and Rad3 related (ATR) has an established role in the DNA damage response of various cancers, its clinical and prognostic significance in ovarian cancer remains largely unknown. The aims of this study were t
Externí odkaz:
https://doaj.org/article/ea0a86d0766146d1a0147463401f670a
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
PurposeChordomas are rare, slow-growing sarcomas without any accepted prognostic biomarkers. Owing to their proximity to critical neurovascular structures, discovering predictive biomarkers in chordoma has been a significant research effort because i
Externí odkaz:
https://doaj.org/article/eb53ec3fc05a48059616c95aa01a5206
Autor:
Xiaoyang Li, Dylan C. Dean, Gregory M. Cote, Lee Zou, Francis J. Hornicek, Shengji Yu, Zhenfeng Duan
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Ataxia-telangiectasia and Rad3 related protein kinase (ATR) is an essential regulator of the DNA damage response in various cancers; however, its expression and roles in osteosarcoma are unclear. We therefore chose to evaluate the signifi
Externí odkaz:
https://doaj.org/article/2d822bbd82db4cf9909685368289b740
Autor:
Wenlong Feng, Dylan C. Dean, Francis J. Hornicek, Dimitrios Spentzos, Robert M. Hoffman, Huirong Shi, Zhenfeng Duan
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Externí odkaz:
https://doaj.org/article/e5c1c811be564cdabef524a29dd6db6f
Publikováno v:
Journal of Bone Oncology, Vol 15, Iss , Pp - (2019)
Bone sarcomas are a collection of sporadic malignancies of mesenchymal origin. The most common subtypes include osteosarcoma, Ewing sarcoma, chondrosarcoma, and chordoma. Despite the use of aggressive treatment protocols consisting of extensive surgi
Externí odkaz:
https://doaj.org/article/a1aa91af70264afcba61066a037c6a44
Autor:
Francis J. Hornicek, Ran Wei, Noah Federman, Pichaya Thanindratarn, Dylan C. Dean, Arun S. Singh, Scott D. Nelson, Zhenfeng Duan
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3721-3737 (2021)
Molecular Oncology
Molecular Oncology
T‐lymphokine‐activated killer (T‐LAK) cell‐originated protein kinase (TOPK) is an emerging target with critical roles in various cancers; however, its expression and function in osteosarcoma remain unexplored. We evaluated TOPK expression usi