Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dylan Burdette"'
Publikováno v:
Biochemistry
Potassium channels allow for the passive movement of potassium ions across the cell membrane and are instrumental in controlling the membrane potential in all cell types. Quaternary ammonium (QA) compounds block potassium channels and have long been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b33d2d2b5ca36bf3807138265967bac
https://doi.org/10.1021/bi500525s
https://doi.org/10.1021/bi500525s
Publikováno v:
Journal of General Virology. 93:235-246
Interleukin-1β (IL-1β) is a potent pro-inflammatory cytokine involved in the pathogenesis of HCV, but the sensors and underlying mechanisms that facilitate HCV-induced IL-1β proteolytic activation and secretion remains unclear. In this study, we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3949890b0d2654790499eb3e83024ea6
https://doi.org/10.1099/vir.0.034033-0
https://doi.org/10.1099/vir.0.034033-0
Publikováno v:
Journal of General Virology. 91:681-690
Oxidative stress has been implicated in various human diseases, including the pathogenesis of hepatitis C virus (HCV). Previous studies have shown the induction of oxidative stress in cultured cells expressing HCV genes. The transcription factor Nrf2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::615d7594aee154cbed38f2ed876c0b10
https://doi.org/10.1099/vir.0.014340-0
https://doi.org/10.1099/vir.0.014340-0
Autor:
Santipongse Chatchavalvanich, Panfeng Fu, Dylan Burdette, Konstantin G. Birukov, Anna A. Birukova, Valery N. Bochkov, Olga Oskolkova
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 292:L924-L935
We have previously described protective effects of oxidized 1-palmitoyl-2-arachidonoyl- sn-glycero-3-phosphocholine (OxPAPC) on pulmonary endothelial cell (EC) barrier function and demonstrated the critical role of cyclopentenone-containing modificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b1c401940030a78d7e1c36f4b03784
https://doi.org/10.1152/ajplung.00395.2006
https://doi.org/10.1152/ajplung.00395.2006
Autor:
Dylan, Burdette, Adrian, Gross
Publikováno v:
Methods in enzymology. 564
Potassium channels are the ion channels most extensively studied by structural techniques. Whereas high-resolution crystal structures have provided key insights into the molecular architecture of these channels, spin labeling studies have helped to u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e27564eff74da714d0869c6585822b90
https://pubmed.ncbi.nlm.nih.gov/26477258
https://pubmed.ncbi.nlm.nih.gov/26477258
Autor:
Dylan Burdette, Adrian Gross
Potassium channels are the ion channels most extensively studied by structural techniques. Whereas high-resolution crystal structures have provided key insights into the molecular architecture of these channels, spin labeling studies have helped to u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::962f62360eea14f96b38df8a8f2a9b89
https://doi.org/10.1016/bs.mie.2015.06.005
https://doi.org/10.1016/bs.mie.2015.06.005
Autor:
Dylan Burdette, Adrian Gross
Publikováno v:
Biophysical Journal. 106(2)
When the potassium channel KcsA transitions from the closed to the open state, the inner helices transition outward and away from the axis of symmetry. This substantial conformational change can be expected to significantly alter the both the shape a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688e63075c4984ad48c8cb472c0dfdfa
Autor:
Dylan Burdette, Adrian Gross
Publikováno v:
Biophysical Journal. 110:601a
During a gating event, the voltage gated potassium channel KvAP undergoes a conformational change in the voltage sensor (helices 1-4), causing the opening of the pore domain (helices 5-6). Throughout this conformational change, the extracellular port
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d772a34329b674ca02938e66499b65e
https://doi.org/10.1016/j.bpj.2015.11.3210
https://doi.org/10.1016/j.bpj.2015.11.3210
RacGTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP
Autor:
Anna A. Birukova, Nurgul Moldobaeva, Junjie Xing, Panfeng Fu, Dylan Burdette, Konstantin G. Birukov
Elevation in intracellular cAMP level has been associated with increased endothelial barrier integrity and linked to the activation of protein kinase A (PKA). Recent studies have shown a novel mechanism of cAMP-mediated endothelial barrier regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce10d183595ae0151a810803a166fcb4
https://europepmc.org/articles/PMC2828820/
https://europepmc.org/articles/PMC2828820/
Autor:
Dylan Burdette, Adrian Gross
Publikováno v:
Biophysical Journal. 108:119a
We have used stopped flow spectrophotometry to measure the binding affinities of quaternary ammonium (QA) ions to the KcsA potassium channel. KcsA is a pH sensitive channel that activates at low pH and then inactivates rapidly. In membranes containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6529c3032d6b48b5dbd28fc028c5844
https://doi.org/10.1016/j.bpj.2014.11.668
https://doi.org/10.1016/j.bpj.2014.11.668