Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dylan, Plaskon"'
Autor:
Amanda C. Drennan, Irina A. Shkel, Clare Kai Cimperman, Sara Heitkamp, M. A. Sridevi, M. T. Record, Katelyn Callies, Hui Wang, Dylan Plaskon, Munish Chhabra, Christina McNerney, Raashi Sreenivasan
Publikováno v:
Biochemistry. 59:1565-1581
FRET (fluorescence resonance energy transfer) between far-upstream(-100) and downstream(+14) cyanine dyes showed extensive bending/wrapping of λPR promoter DNA on E. coli RNA polymerase (RNAP) in c...
Autor:
Dylan Plaskon, Claire Evensen, Kate Henderson, Benjamin Palatnik, Takahiro Ishikuri, Hao-Che Wang, Sarah Doughty, M. Thomas Record Jr.
Publikováno v:
Journal of molecular biology. 434(13)
An understanding of the kinetics and mechanism of bacterial transcription initiation is needed to understand regulation of gene expression and advance fields from antibiotic discovery to promoter design. The step-by-step forward kinetics and mechanis
Autor:
Kate L. Henderson, Claire Evensen, Lindsey C. Felth, Irina A. Shkel, Cristen Molzahn, Dylan Plaskon, M. Thomas Record, Sarah Dyke
Publikováno v:
Proc Natl Acad Sci U S A
Transcription initiation is highly regulated by promoter sequence, transcription factors, and ligands. All known transcription inhibitors, an important class of antibiotics, act in initiation. To understand regulation and inhibition, the biophysical
Autor:
Kate L. Henderson, Sarah Dyke, Irina A. Shkel, Claire Evensen, Cristen Molzahn, Lindsey C. Felth, M. Thomas Record, Dylan Plaskon
In transcription initiation, specific contacts between RNA polymerase (RNAP) and promoter DNA are disrupted as the RNA-DNA hybrid advances into the cleft, resulting in escape of RNAP. From the pattern of large and small rate constants for steps of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287649487651eb36b82def82b04ae2ca
https://doi.org/10.1101/2020.09.11.293670
https://doi.org/10.1101/2020.09.11.293670
Autor:
Raashi, Sreenivasan, Irina A, Shkel, Munish, Chhabra, Amanda, Drennan, Sara, Heitkamp, Hao-Che, Wang, Malavika A, Sridevi, Dylan, Plaskon, Christina, McNerney, Katelyn, Callies, Clare K, Cimperman, M Thomas, Record
Publikováno v:
Biochemistry
FRET (fluorescence resonance energy transfer) between far-upstream(−100) and downstream(+14) cyanine dyes showed extensive bending/wrapping of λP(R) promoter DNA on E. coli RNA polymerase (RNAP) in closed and open complexes (CC, OC). Here we deter
Autor:
Katelyn Callies, Munish Chhabra, Irina A. Shkel, M. T. Record, Christina McNerney, M. A. Sridevi, Hui Wang, Raashi Sreenivasan, Amanda C. Drennan, Dylan Plaskon, Clare Kai Cimperman, Sara Heitkamp
FRET (fluorescence energy transfer) between far-upstream (-100) and downstream (+14) cyanine dyes showed extensive bending/wrapping of λPR promoter DNA on E. coli RNA polymerase (RNAP) in closed and open complexes (CC, OC). Here we determine the kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0b9b7c1cb1d653b07bd1954c117858
https://doi.org/10.1101/2020.02.04.932780
https://doi.org/10.1101/2020.02.04.932780
Autor:
Dylan Plaskon, M. Thomas Record, Benjamin Palatnik, Kate L. Henderson, Taka Ishikuri, Claire Evensen
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Aziz Taghbalout, Dylan Plaskon, Wenbo Wang, Nathaniel Jillette, Yasuhiro Fujiwara, Albert W. Cheng, Haoyi Wang, Phoebe Lee
Publikováno v:
Cell Research
Autor:
Kevin P. Rice, Colin T. Sheehan, Dylan Plaskon, Dylan J. Cincotta, Ryan A. Weeks, Connor P. McGuckin, Rachel M. Guerra, Vania Lopez Ruiz
Publikováno v:
Cancer Research. 75:2444-2444
A significant fraction of oncologists’ chemotherapeutic arsenal consists of agents that cause DNA damage. Repair proteins that recognize aberrant DNA structural features mitigate this damage and thus the efficacy of such anticancer drugs. DNA damag