A Dedicated 21-Plex Proximity Extension Assay Panel for High-Sensitivity Protein Biomarker Detection Using Microdialysis in Severe Traumatic Brain Injury : The Next Step in Precision Medicine?

Autor: Dyhrfort, Philip, Svedung-Wettervik, Teodor, Clausen, Fredrik, Enblad, Per, Hillered, Lars, Lewén, Anders

Cerebral protein profiling in traumatic brain injury (TBI) is needed to better comprehend secondary injury pathways. Cerebral microdialysis (CMD), in combination with the proximity extension assay (PEA) technique, has great potential in this field. B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______361::051c949bf1e802ffdc5cf32179504eed
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-497708

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid.

Autor: Dyhrfort P; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Lindblad C; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Department of Neurosurgery, Uppsala University Hospital, Uppsala, Sweden.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Neurosciences, Addenbrooke's Hospital, Cambridge University, Turku, Finland., Widgren A; Department of Chemistry-BMC, Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden., Virhammar J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Department of Neurology, Uppsala University Hospital, Uppsala, Sweden., Piehl F; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Center for Neurology, Academic Specialist Center, Stockholm, Sweden., Bergquist J; Department of Chemistry-BMC, Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden., Al Nimer F; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Center for Neurology, Academic Specialist Center, Stockholm, Sweden., Rostami E; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Department of Neurosurgery, Uppsala University Hospital, Uppsala, Sweden.; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: Neurotrauma reports [Neurotrauma Rep] 2024 Sep 20; Vol. 5 (1), pp. 857-873. Date of Electronic Publication: 2024 Sep 20 (Print Publication: 2024).

Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care.

Autor: Dyhrfort P; Department of Neuroscience, Section of Neurosurgery, Uppsala University, Uppsala, Sweden., Shen Q; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Clausen F; Department of Neuroscience, Section of Neurosurgery, Uppsala University, Uppsala, Sweden., Thulin M; Department of Statistics Uppsala University, Uppsala, Sweden.; School of Mathematics and Maxwell Institute for Mathematical Sciences, University of Edinburgh, Edinburgh, United Kingdom., Enblad P; Department of Neuroscience, Section of Neurosurgery, Uppsala University, Uppsala, Sweden., Kamali-Moghaddam M; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lewén A; Department of Neuroscience, Section of Neurosurgery, Uppsala University, Uppsala, Sweden., Hillered L; Department of Neuroscience, Section of Neurosurgery, Uppsala University, Uppsala, Sweden.

Publikováno v: Journal of neurotrauma [J Neurotrauma] 2019 Oct 15; Vol. 36 (20), pp. 2872-2885. Date of Electronic Publication: 2019 Jun 17.